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Items: 1 to 20 of 45

1.

Acute myeloid leukemia - strategies and challenges for targeting oncogenic Hedgehog/GLI signaling.

Aberger F, Hutterer E, Sternberg C, Del Burgo PJ, Hartmann TN.

Cell Commun Signal. 2017 Jan 25;15(1):8. doi: 10.1186/s12964-017-0163-4. Review.

2.

IKBKE Is Required during KRAS-Induced Pancreatic Tumorigenesis.

Rajurkar M, Dang K, Fernandez-Barrena MG, Liu X, Fernandez-Zapico ME, Lewis BC, Mao J.

Cancer Res. 2017 Jan 15;77(2):320-329. doi: 10.1158/0008-5472.CAN-15-1684.

PMID:
28069799
3.

Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation.

Wang Y, Hsu JM, Kang Y, Wei Y, Lee PC, Chang SJ, Hsu YH, Hsu JL, Wang HL, Chang WC, Li CW, Liao HW, Chang SS, Xia W, Ko HW, Chou CK, Fleming JB, Wang H, Hwang RF, Chen Y, Qin J, Hung MC.

Cancer Res. 2016 Dec 1;76(23):7049-7058.

PMID:
27758883
4.

DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome.

Duchon A, Herault Y.

Front Behav Neurosci. 2016 Jun 3;10:104. doi: 10.3389/fnbeh.2016.00104. Review.

5.

DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis.

Fernández-Martínez P, Zahonero C, Sánchez-Gómez P.

Mol Cell Oncol. 2015 Jan 30;2(1):e970048. doi: 10.4161/23723548.2014.970048. Review.

6.

Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors.

Rimkus TK, Carpenter RL, Qasem S, Chan M, Lo HW.

Cancers (Basel). 2016 Feb 15;8(2). pii: E22. doi: 10.3390/cancers8020022. Review.

7.

DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.

Gruber W, Hutzinger M, Elmer DP, Parigger T, Sternberg C, Cegielkowski L, Zaja M, Leban J, Michel S, Hamm S, Vitt D, Aberger F.

Oncotarget. 2016 Feb 9;7(6):7134-48. doi: 10.18632/oncotarget.6910.

8.

DYRK1A Controls HIV-1 Replication at a Transcriptional Level in an NFAT Dependent Manner.

Booiman T, Loukachov VV, van Dort KA, van 't Wout AB, Kootstra NA.

PLoS One. 2015 Dec 7;10(12):e0144229. doi: 10.1371/journal.pone.0144229.

9.

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1.

Schneider P, Bayo-Fina JM, Singh R, Kumar Dhanyamraju P, Holz P, Baier A, Fendrich V, Ramaswamy A, Baumeister S, Martinez ED, Lauth M.

Nat Commun. 2015 Aug 27;6:8023. doi: 10.1038/ncomms9023. Erratum in: Nat Commun. 2015;6:8741.

10.

Osteogenesis and neurogenesis: a robust link also for language evolution.

Boeckx C, Benítez-Burraco A.

Front Cell Neurosci. 2015 Jul 28;9:291. doi: 10.3389/fncel.2015.00291. No abstract available.

11.

Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy.

Pandolfi S, Stecca B.

Expert Rev Mol Med. 2015 Feb 9;17:e5. doi: 10.1017/erm.2015.3. Review.

12.

Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy.

Aberger F, Ruiz I Altaba A.

Semin Cell Dev Biol. 2014 Sep;33:93-104. doi: 10.1016/j.semcdb.2014.05.003. Review.

13.

Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A).

Kaczmarski W, Barua M, Mazur-Kolecka B, Frackowiak J, Dowjat W, Mehta P, Bolton D, Hwang YW, Rabe A, Albertini G, Wegiel J.

J Neurosci Res. 2014 Feb;92(2):162-73. doi: 10.1002/jnr.23279.

14.
15.

Expression analysis of multiple myeloma CD138 negative progenitor cells using single molecule microarray readout.

Jacak J, Schnidar H, Muresan L, Regl G, Frischauf A, Aberger F, Schütz GJ, Hesse J.

J Biotechnol. 2013 Apr 15;164(4):525-30. doi: 10.1016/j.jbiotec.2013.01.027.

16.

Overexpression of Gli1 in cancer interstitial tissues predicts early relapse after radical operation of breast cancer.

Li YH, Gao HF, Wang Y, Liu F, Tian XF, Zhang Y.

Chin J Cancer Res. 2012 Dec;24(4):263-74. doi: 10.3978/j.issn.1000-9604.2012.10.04.

17.

RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling.

Shimokawa T, Rahman MF, Tostar U, Sonkoly E, Ståhle M, Pivarcsi A, Palaniswamy R, Zaphiropoulos PG.

RNA Biol. 2013 Feb;10(2):321-33. doi: 10.4161/rna.23343.

18.

Identification, functional characterization, and pathobiological significance of GLI1 isoforms in human cancers.

Carpenter RL, Lo HW.

Vitam Horm. 2012;88:115-40. doi: 10.1016/B978-0-12-394622-5.00006-7.

19.

The role of mirk kinase in sarcomas.

Friedman E.

Sarcoma. 2011;2011:260757. doi: 10.1155/2011/260757.

20.

Genome-wide association study identifies single nucleotide polymorphism in DYRK1A associated with replication of HIV-1 in monocyte-derived macrophages.

Bol SM, Moerland PD, Limou S, van Remmerden Y, Coulonges C, van Manen D, Herbeck JT, Fellay J, Sieberer M, Sietzema JG, van 't Slot R, Martinson J, Zagury JF, Schuitemaker H, van 't Wout AB.

PLoS One. 2011 Feb 25;6(2):e17190. doi: 10.1371/journal.pone.0017190.

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