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Safety Profiles of Tripterygium wilfordii Hook F: A Systematic Review and Meta-Analysis.

Zhang C, Sun PP, Guo HT, Liu Y, Li J, He XJ, Lu AP.

Front Pharmacol. 2016 Nov 8;7:402.


Tripterygium wilfordii Hook F versus conventional synthetic disease-modifying anti-rheumatic drugs as monotherapy for rheumatoid arthritis: a systematic review and network meta-analysis.

Wang HL, Jiang Q, Feng XH, Zhang HD, Ge L, Luo CG, Gong X, Li B.

BMC Complement Altern Med. 2016 Jul 13;16:215. doi: 10.1186/s12906-016-1194-x.


Fabrication of novel vesicles of triptolide for antirheumatoid activity with reduced toxicity in vitro and in vivo.

Zhang L, Wang T, Li Q, Huang J, Xu H, Li J, Wang Y, Liang Q.

Int J Nanomedicine. 2016 Jun 8;11:2663-73. doi: 10.2147/IJN.S104593.


Immunosuppressive, anti-inflammatory and anti-cancer properties of triptolide: A mini review.

Ziaei S, Halaby R.

Avicenna J Phytomed. 2016 Mar-Apr;6(2):149-64. Review.


Challenges and guidelines for clinical trial of herbal drugs.

Parveen A, Parveen B, Parveen R, Ahmad S.

J Pharm Bioallied Sci. 2015 Oct-Dec;7(4):329-33. doi: 10.4103/0975-7406.168035. Review.


Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts.

Patil S, Lis LG, Schumacher RJ, Norris BJ, Morgan ML, Cuellar RA, Blazar BR, Suryanarayanan R, Gurvich VJ, Georg GI.

J Med Chem. 2015 Dec 10;58(23):9334-44. doi: 10.1021/acs.jmedchem.5b01329.


Fcγ and Complement Receptors and Complement Proteins in Neutrophil Activation in Rheumatoid Arthritis: Contribution to Pathogenesis and Progression and Modulation by Natural Products.

Paoliello-Paschoalato AB, Marchi LF, de Andrade MF, Kabeya LM, Donadi EA, Lucisano-Valim YM.

Evid Based Complement Alternat Med. 2015;2015:429878. doi: 10.1155/2015/429878. Review.


Demethylzeylasteral (T-96) Treatment Ameliorates Mice Lupus Nephritis Accompanied by Inhibiting Activation of NF-κB Pathway.

Hu Q, Yang C, Wang Q, Zeng H, Qin W.

PLoS One. 2015 Jul 24;10(7):e0133724. doi: 10.1371/journal.pone.0133724.


Celastrol inhibits inflammatory stimuli-induced neutrophil extracellular trap formation.

Yu Y, Koehn CD, Yue Y, Li S, Thiele GM, Hearth-Holmes MP, Mikuls TR, O'Dell JR, Klassen LW, Zhang Z, Su K.

Curr Mol Med. 2015;15(4):401-10.


Triptolide ameliorates colonic fibrosis in an experimental rat model.

Tao Q, Wang B, Zheng Y, Li G, Ren J.

Mol Med Rep. 2015 Aug;12(2):1891-7. doi: 10.3892/mmr.2015.3582.


Celastrol supports survival of retinal ganglion cells injured by optic nerve crush.

Kyung H, Kwong JM, Bekerman V, Gu L, Yadegari D, Caprioli J, Piri N.

Brain Res. 2015 Jun 3;1609:21-30. doi: 10.1016/j.brainres.2015.03.032.


Evaluation of traditional medicines for neurodegenerative diseases using Drosophila models.

Lee S, Bang SM, Lee JW, Cho KS.

Evid Based Complement Alternat Med. 2014;2014:967462. doi: 10.1155/2014/967462. Review.


Extracts of Tripterygium wilfordii Hook F in the Treatment of Rheumatoid Arthritis: A Systemic Review and Meta-Analysis of Randomised Controlled Trials.

Liu Y, Tu S, Gao W, Wang Y, Liu P, Hu Y, Dong H.

Evid Based Complement Alternat Med. 2013;2013:410793. doi: 10.1155/2013/410793. Review.


Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase.

Lin Y, Peng N, Li J, Zhuang H, Hua ZC.

Mol Cancer. 2013 Jun 8;12:54. doi: 10.1186/1476-4598-12-54.


Anti-inflammatory effects of triptolide improve left ventricular function in a rat model of diabetic cardiomyopathy.

Wen HL, Liang ZS, Zhang R, Yang K.

Cardiovasc Diabetol. 2013 Mar 25;12:50. doi: 10.1186/1475-2840-12-50.


Triptolide Transcriptionally Represses HER2 in Ovarian Cancer Cells by Targeting NF-κB.

Ou CC, Chen YW, Hsu SC, Sytwu HK, Loh SH, Li JW, Liu JY.

Evid Based Complement Alternat Med. 2012;2012:350239. doi: 10.1155/2012/350239.


Lipophilic stinging nettle extracts possess potent anti-inflammatory activity, are not cytotoxic and may be superior to traditional tinctures for treating inflammatory disorders.

Johnson TA, Sohn J, Inman WD, Bjeldanes LF, Rayburn K.

Phytomedicine. 2013 Jan 15;20(2):143-7. doi: 10.1016/j.phymed.2012.09.016.

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