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Items: 1 to 20 of 92


Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia.

Jiang X, Hu C, Ferchen K, Nie J, Cui X, Chen CH, Cheng L, Zuo Z, Seibel W, He C, Tang Y, Skibbe JR, Wunderlich M, Reinhold WC, Dong L, Shen C, Arnovitz S, Ulrich B, Lu J, Weng H, Su R, Huang H, Wang Y, Li C, Qin X, Mulloy JC, Zheng Y, Diao J, Jin J, Li C, Liu PP, He C, Chen Y, Chen J.

Nat Commun. 2017 Dec 13;8(1):2099. doi: 10.1038/s41467-017-02290-w. Erratum in: Nat Commun. 2018 Feb 9;9(1):670.


TET1 inhibits cell proliferation by inducing RASSF5 expression.

Li BT, Yu C, Xu Y, Liu SB, Fan HY, Pan WW.

Oncotarget. 2017 Sep 23;8(49):86395-86409. doi: 10.18632/oncotarget.21189. eCollection 2017 Oct 17.


New Insights into 5hmC DNA Modification: Generation, Distribution and Function.

Shi DQ, Ali I, Tang J, Yang WC.

Front Genet. 2017 Jul 19;8:100. doi: 10.3389/fgene.2017.00100. eCollection 2017. Review.


Potential coordination role between O-GlcNAcylation and epigenetics.

Wu D, Cai Y, Jin J.

Protein Cell. 2017 Oct;8(10):713-723. doi: 10.1007/s13238-017-0416-4. Epub 2017 May 9. Review.


The chemistries and consequences of DNA and RNA methylation and demethylation.

Traube FR, Carell T.

RNA Biol. 2017 Sep 2;14(9):1099-1107. doi: 10.1080/15476286.2017.1318241. Epub 2017 Apr 25.


DNA methylation aberrancies as a guide for surveillance and treatment of human cancers.

Liang G, Weisenberger DJ.

Epigenetics. 2017 Jun 3;12(6):416-432. doi: 10.1080/15592294.2017.1311434. Epub 2017 Mar 30. Review.


Characterization of TET and IDH gene expression in chronic lymphocytic leukemia: comparison with normal B cells and prognostic significance.

Van Damme M, Crompot E, Meuleman N, Maerevoet M, Mineur P, Bron D, Lagneaux L, Stamatopoulos B.

Clin Epigenetics. 2016 Dec 7;8:132. eCollection 2016.


The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation.

Zheng L, Zhai Y, Li N, Ma F, Zhu H, Du X, Li G, Hua J.

Sci Rep. 2016 Nov 18;6:37414. doi: 10.1038/srep37414.


The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia.

Sperling AS, Gibson CJ, Ebert BL.

Nat Rev Cancer. 2017 Jan;17(1):5-19. doi: 10.1038/nrc.2016.112. Epub 2016 Nov 11. Review.


Epigenetics of hematopoiesis and hematological malignancies.

Hu D, Shilatifard A.

Genes Dev. 2016 Sep 15;30(18):2021-2041. Review.


DNMT3A and TET2 in the Pre-Leukemic Phase of Hematopoietic Disorders.

Sato H, Wheat JC, Steidl U, Ito K.

Front Oncol. 2016 Aug 22;6:187. doi: 10.3389/fonc.2016.00187. eCollection 2016. Review.


The emerging insights into catalytic or non-catalytic roles of TET proteins in tumors and neural development.

Lian H, Li WB, Jin WL.

Oncotarget. 2016 Sep 27;7(39):64512-64525. doi: 10.18632/oncotarget.11412. Review.


Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes.

Etchegaray JP, Mostoslavsky R.

Mol Cell. 2016 Jun 2;62(5):695-711. doi: 10.1016/j.molcel.2016.05.029. Review.


DNA methylation in hematopoietic development and disease.

Gore AV, Weinstein BM.

Exp Hematol. 2016 Sep;44(9):783-90. doi: 10.1016/j.exphem.2016.04.013. Epub 2016 May 10. Review.


Role of TET enzymes in DNA methylation, development, and cancer.

Rasmussen KD, Helin K.

Genes Dev. 2016 Apr 1;30(7):733-50. doi: 10.1101/gad.276568.115. Review.


The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms.

Haag T, Richter AM, Schneider MB, Jiménez AP, Dammann RH.

BMC Cancer. 2016 Feb 1;16:49. doi: 10.1186/s12885-016-2087-6.


Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia.

Huang H, Jiang X, Wang J, Li Y, Song CX, Chen P, Li S, Gurbuxani S, Arnovitz S, Wang Y, Weng H, Neilly MB, He C, Li Z, Chen J.

Cancer Lett. 2016 Mar 28;372(2):157-65. doi: 10.1016/j.canlet.2015.12.032. Epub 2016 Jan 11.


DNA methylation and hydroxymethylation in hematologic differentiation and transformation.

Ko M, An J, Rao A.

Curr Opin Cell Biol. 2015 Dec;37:91-101. doi: 10.1016/ Epub 2015 Nov 18. Review.


Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.

Zhao Z, Chen L, Dawlaty MM, Pan F, Weeks O, Zhou Y, Cao Z, Shi H, Wang J, Lin L, Chen S, Yuan W, Qin Z, Ni H, Nimer SD, Yang FC, Jaenisch R, Jin P, Xu M.

Cell Rep. 2015 Nov 24;13(8):1692-704. doi: 10.1016/j.celrep.2015.10.037. Epub 2015 Nov 12.


Functions of TET Proteins in Hematopoietic Transformation.

Han JA, An J, Ko M.

Mol Cells. 2015 Nov;38(11):925-35. doi: 10.14348/molcells.2015.0294. Epub 2015 Nov 10. Review.

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