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Items: 1 to 20 of 29


A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity.

Gasri-Plotnitsky L, Ovadia A, Shamalov K, Nizri-Megnaji T, Meir S, Zurer I, Cohen CJ, Ginsberg D.

Oncotarget. 2017 Apr 4;8(14):23775-23786. doi: 10.18632/oncotarget.15864.


p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma.

Hideshima T, Cottini F, Nozawa Y, Seo HS, Ohguchi H, Samur MK, Cirstea D, Mimura N, Iwasawa Y, Richardson PG, Munshi NC, Chauhan D, Massefski W, Utsugi T, Dhe-Paganon S, Anderson KC.

Blood. 2017 Mar 9;129(10):1308-1319. doi: 10.1182/blood-2016-09-738500. Epub 2017 Jan 12.


Most of the tight positional conservation of transcription factor binding sites near the transcription start site reflects their co-localization within regulatory modules.

Acevedo-Luna N, Mariño-Ramírez L, Halbert A, Hansen U, Landsman D, Spouge JL.

BMC Bioinformatics. 2016 Nov 21;17(1):479.


Identification of hub genes and regulatory factors of glioblastoma multiforme subgroups by RNA-seq data analysis.

Li Y, Min W, Li M, Han G, Dai D, Zhang L, Chen X, Wang X, Zhang Y, Yue Z, Liu J.

Int J Mol Med. 2016 Oct;38(4):1170-8. doi: 10.3892/ijmm.2016.2717. Epub 2016 Aug 26.


DNA methyltransferase 3A promotes cell proliferation by silencing CDK inhibitor p18INK4C in gastric carcinogenesis.

Cui H, Zhao C, Gong P, Wang L, Wu H, Zhang K, Zhou R, Wang L, Zhang T, Zhong S, Fan H.

Sci Rep. 2015 Sep 9;5:13781. doi: 10.1038/srep13781.


Characterization of ERM transactivation domain binding to the ACID/PTOV domain of the Mediator subunit MED25.

Landrieu I, Verger A, Baert JL, Rucktooa P, Cantrelle FX, Dewitte F, Ferreira E, Lens Z, Villeret V, Monté D.

Nucleic Acids Res. 2015 Aug 18;43(14):7110-21. doi: 10.1093/nar/gkv650. Epub 2015 Jun 29.


Transcriptional control of stem cell fate by E2Fs and pocket proteins.

Julian LM, Blais A.

Front Genet. 2015 Apr 28;6:161. doi: 10.3389/fgene.2015.00161. eCollection 2015. Review.


Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans.

Shi L, Li M, Lin Q, Qi X, Su B.

BMC Biol. 2013 May 22;11:62. doi: 10.1186/1741-7007-11-62.


The Mediator complex subunit MED25 is targeted by the N-terminal transactivation domain of the PEA3 group members.

Verger A, Baert JL, Verreman K, Dewitte F, Ferreira E, Lens Z, de Launoit Y, Villeret V, Monté D.

Nucleic Acids Res. 2013 May;41(9):4847-59. doi: 10.1093/nar/gkt199. Epub 2013 Mar 26.


Genetic variation at a Yin-Yang 1 response site regulates the transcription of cyclin-dependent kinase inhibitor p18INK4C transcript in lupus-prone mice.

Potula HH, Morel L.

J Immunol. 2012 May 15;188(10):4992-5002. doi: 10.4049/jimmunol.1101992. Epub 2012 Apr 13.


Contrasting behavior of the p18INK4c and p16INK4a tumor suppressors in both replicative and oncogene-induced senescence.

Gagrica S, Brookes S, Anderton E, Rowe J, Peters G.

Cancer Res. 2012 Jan 1;72(1):165-75. doi: 10.1158/0008-5472.CAN-11-2552. Epub 2011 Nov 11.


E2F1-mediated upregulation of p19INK4d determines its periodic expression during cell cycle and regulates cellular proliferation.

Carcagno AL, Marazita MC, Ogara MF, Ceruti JM, Sonzogni SV, Scassa ME, Giono LE, Cánepa ET.

PLoS One. 2011;6(7):e21938. doi: 10.1371/journal.pone.0021938. Epub 2011 Jul 13.


Cyclin-dependent kinase inhibitor Cdkn2c regulates B cell homeostasis and function in the NZM2410-derived murine lupus susceptibility locus Sle2c1.

Xu Z, Potula HH, Vallurupalli A, Perry D, Baker H, Croker BP, Dozmorov I, Morel L.

J Immunol. 2011 Jun 15;186(12):6673-82. doi: 10.4049/jimmunol.1002544. Epub 2011 May 4.


Upregulation of p18Ink4c expression by oncogenic HPV E6 via p53-miR-34a pathway.

Wang X, Meyers C, Guo M, Zheng ZM.

Int J Cancer. 2011 Sep 15;129(6):1362-72. doi: 10.1002/ijc.25800. Epub 2011 Feb 26.


N-Myc is a downstream target of RET signaling and is required for transcriptional regulation of p18(Ink4c) by the transforming mutant RET(C634R).

Kulkarni MV, Franklin DS.

Mol Oncol. 2011 Feb;5(1):24-35. doi: 10.1016/j.molonc.2010.10.004. Epub 2010 Nov 5.


Cooperation between myogenic regulatory factors and SIX family transcription factors is important for myoblast differentiation.

Liu Y, Chu A, Chakroun I, Islam U, Blais A.

Nucleic Acids Res. 2010 Nov;38(20):6857-71. doi: 10.1093/nar/gkq585. Epub 2010 Jul 2.


Overexpression of transcription factor Sp1 leads to gene expression perturbations and cell cycle inhibition.

Deniaud E, Baguet J, Chalard R, Blanquier B, Brinza L, Meunier J, Michallet MC, Laugraud A, Ah-Soon C, Wierinckx A, Castellazzi M, Lachuer J, Gautier C, Marvel J, Leverrier Y.

PLoS One. 2009 Sep 15;4(9):e7035. doi: 10.1371/journal.pone.0007035.


EKLF/KLF1 controls cell cycle entry via direct regulation of E2f2.

Tallack MR, Keys JR, Humbert PO, Perkins AC.

J Biol Chem. 2009 Jul 31;284(31):20966-74. doi: 10.1074/jbc.M109.006346. Epub 2009 May 20.


Conspirators in a capital crime: co-deletion of p18INK4c and p16INK4a/p14ARF/p15INK4b in glioblastoma multiforme.

Solomon DA, Kim JS, Jean W, Waldman T.

Cancer Res. 2008 Nov 1;68(21):8657-60. doi: 10.1158/0008-5472.CAN-08-2084. Review.


Transcriptional repression of the prosurvival endoplasmic reticulum chaperone GRP78/BIP by E2F1.

Racek T, Buhlmann S, Rüst F, Knoll S, Alla V, Pützer BM.

J Biol Chem. 2008 Dec 5;283(49):34305-14. doi: 10.1074/jbc.M803925200. Epub 2008 Oct 7.

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