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Items: 1 to 20 of 69


Treating the Synapse in Major Psychiatric Disorders: The Role of Postsynaptic Density Network in Dopamine-Glutamate Interplay and Psychopharmacologic Drugs Molecular Actions.

Tomasetti C, Iasevoli F, Buonaguro EF, De Berardis D, Fornaro M, Fiengo AL, Martinotti G, Orsolini L, Valchera A, Di Giannantonio M, de Bartolomeis A.

Int J Mol Sci. 2017 Jan 12;18(1). pii: E135. doi: 10.3390/ijms18010135. Review.


Actin-Dependent Alterations of Dendritic Spine Morphology in Shankopathies.

Sarowar T, Grabrucker AM.

Neural Plast. 2016;2016:8051861. Review.


The Neurobiological Basis for Social Affiliation in Autism Spectrum Disorder and Schizophrenia.

Crider A, Pillai A.

Curr Behav Neurosci Rep. 2016 Jun;3(2):154-164.


Shank3 Is Part of a Zinc-Sensitive Signaling System That Regulates Excitatory Synaptic Strength.

Arons MH, Lee K, Thynne CJ, Kim SA, Schob C, Kindler S, Montgomery JM, Garner CC.

J Neurosci. 2016 Aug 31;36(35):9124-34. doi: 10.1523/JNEUROSCI.0116-16.2016.


Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function.

Jaramillo TC, Speed HE, Xuan Z, Reimers JM, Escamilla CO, Weaver TP, Liu S, Filonova I, Powell CM.

Autism Res. 2017 Jan;10(1):42-65. doi: 10.1002/aur.1664.


Human Pluripotent Stem Cell-derived Cortical Neurons for High Throughput Medication Screening in Autism: A Proof of Concept Study in SHANK3 Haploinsufficiency Syndrome.

Darville H, Poulet A, Rodet-Amsellem F, Chatrousse L, Pernelle J, Boissart C, Héron D, Nava C, Perrier A, Jarrige M, Cogé F, Millan MJ, Bourgeron T, Peschanski M, Delorme R, Benchoua A.

EBioMedicine. 2016 Jul;9:293-305. doi: 10.1016/j.ebiom.2016.05.032.


The Shank3 Interaction Partner ProSAPiP1 Regulates Postsynaptic SPAR Levels and the Maturation of Dendritic Spines in Hippocampal Neurons.

Reim D, Weis TM, Halbedl S, Delling JP, Grabrucker AM, Boeckers TM, Schmeisser MJ.

Front Synaptic Neurosci. 2016 May 24;8:13. doi: 10.3389/fnsyn.2016.00013.


Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.

Heise C, Schroeder JC, Schoen M, Halbedl S, Reim D, Woelfle S, Kreutz MR, Schmeisser MJ, Boeckers TM.

Front Cell Neurosci. 2016 Apr 26;10:106. doi: 10.3389/fncel.2016.00106.


Developmental phenotype in Phelan-McDermid (22q13.3 deletion) syndrome: a systematic and prospective study in 34 children.

Zwanenburg RJ, Ruiter SA, van den Heuvel ER, Flapper BC, Van Ravenswaaij-Arts CM.

J Neurodev Disord. 2016 Apr 26;8:16. doi: 10.1186/s11689-016-9150-0.


Neurobiology of social behavior abnormalities in autism and Williams syndrome.

Barak B, Feng G.

Nat Neurosci. 2016 Apr 26;19(6):647-55. doi: 10.1038/nn.4276. Review.


Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.

Sarowar T, Grabrucker S, Föhr K, Mangus K, Eckert M, Bockmann J, Boeckers TM, Grabrucker AM.

Mol Brain. 2016 Mar 11;9:28. doi: 10.1186/s13041-016-0206-6.


Altered Striatal Synaptic Function and Abnormal Behaviour in Shank3 Exon4-9 Deletion Mouse Model of Autism.

Jaramillo TC, Speed HE, Xuan Z, Reimers JM, Liu S, Powell CM.

Autism Res. 2016 Mar;9(3):350-75. doi: 10.1002/aur.1529.


Behavioral phenotypes of genetic mouse models of autism.

Kazdoba TM, Leach PT, Crawley JN.

Genes Brain Behav. 2016 Jan;15(1):7-26. doi: 10.1111/gbb.12256. Review.


Phelan McDermid Syndrome: From Genetic Discoveries to Animal Models and Treatment.

Harony-Nicolas H, De Rubeis S, Kolevzon A, Buxbaum JD.

J Child Neurol. 2015 Dec;30(14):1861-70. doi: 10.1177/0883073815600872. Review.


Expression of imprinted genes in placenta is associated with infant neurobehavioral development.

Green BB, Kappil M, Lambertini L, Armstrong DA, Guerin DJ, Sharp AJ, Lester BM, Chen J, Marsit CJ.

Epigenetics. 2015;10(9):834-41. doi: 10.1080/15592294.2015.1073880.


Phenotypic and functional analysis of SHANK3 stop mutations identified in individuals with ASD and/or ID.

Cochoy DM, Kolevzon A, Kajiwara Y, Schoen M, Pascual-Lucas M, Lurie S, Buxbaum JD, Boeckers TM, Schmeisser MJ.

Mol Autism. 2015 Apr 29;6:23. doi: 10.1186/s13229-015-0020-5.


Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation.

Lee EJ, Lee H, Huang TN, Chung C, Shin W, Kim K, Koh JY, Hsueh YP, Kim E.

Nat Commun. 2015 May 18;6:7168. doi: 10.1038/ncomms8168.


Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian men.

Devaney JM, Wang S, Furbert-Harris P, Apprey V, Ittmann M, Wang BD, Olender J, Lee NH, Kwabi-Addo B.

Epigenetics. 2015;10(4):319-28. doi: 10.1080/15592294.2015.1022019.


Shank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit.

Lee J, Chung C, Ha S, Lee D, Kim DY, Kim H, Kim E.

Front Cell Neurosci. 2015 Mar 19;9:94. doi: 10.3389/fncel.2015.00094.


FMRP interacts with G-quadruplex structures in the 3'-UTR of its dendritic target Shank1 mRNA.

Zhang Y, Gaetano CM, Williams KR, Bassell GJ, Mihailescu MR.

RNA Biol. 2014;11(11):1364-74. doi: 10.1080/15476286.2014.996464.

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