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Items: 1 to 20 of 122


Phosphorylation of ETS-1 is a critical event in DNA polymerase iota-induced invasion and metastasis of esophageal squamous cell carcinoma.

He C, Wu S, Gao A, Su Y, Min H, Shang ZF, Wu J, Yang L, Ding WQ, Zhou J.

Cancer Sci. 2017 Dec;108(12):2503-2510. doi: 10.1111/cas.13399. Epub 2017 Oct 8.


Analyzing the Catalytic Activities and Interactions of Eukaryotic Translesion Synthesis Polymerases.

Powers KT, Washington MT.

Methods Enzymol. 2017;592:329-356. doi: 10.1016/bs.mie.2017.04.002. Epub 2017 May 8.


DNA Polymerases ImuC and DinB Are Involved in DNA Alkylation Damage Tolerance in Pseudomonas aeruginosa and Pseudomonas putida.

Jatsenko T, Sidorenko J, Saumaa S, Kivisaar M.

PLoS One. 2017 Jan 24;12(1):e0170719. doi: 10.1371/journal.pone.0170719. eCollection 2017.


DNA polymerase kappa protects human cells against MMC-induced genotoxicity through error-free translesion DNA synthesis.

Kanemaru Y, Suzuki T, Sassa A, Matsumoto K, Adachi N, Honma M, Numazawa S, Nohmi T.

Genes Environ. 2017 Jan 7;39:6. doi: 10.1186/s41021-016-0067-3. eCollection 2017.


Dosage Mutator Genes in Saccharomyces cerevisiae: A Novel Mutator Mode-of-Action of the Mph1 DNA Helicase.

Ang JS, Duffy S, Segovia R, Stirling PC, Hieter P.

Genetics. 2016 Nov;204(3):975-986. doi: 10.1534/genetics.116.192211. Epub 2016 Aug 31.


Human Translesion Polymerase κ Exhibits Enhanced Activity and Reduced Fidelity Two Nucleotides from G-Quadruplex DNA.

Eddy S, Tillman M, Maddukuri L, Ketkar A, Zafar MK, Eoff RL.

Biochemistry. 2016 Sep 20;55(37):5218-29. doi: 10.1021/acs.biochem.6b00374. Epub 2016 Sep 7.


Translesion Synthesis of the N(2)-2'-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1.

Bose A, Millsap AD, DeLeon A, Rizzo CJ, Basu AK.

Chem Res Toxicol. 2016 Sep 19;29(9):1549-59. doi: 10.1021/acs.chemrestox.6b00221. Epub 2016 Aug 17.


Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase κ.

Jha V, Bian C, Xing G, Ling H.

Nucleic Acids Res. 2016 Jun 2;44(10):4957-67. doi: 10.1093/nar/gkw204. Epub 2016 Mar 31.


Can Peto's paradox be used as the null hypothesis to identify the role of evolution in natural resistance to cancer? A critical review.

Ducasse H, Ujvari B, Solary E, Vittecoq M, Arnal A, Bernex F, Pirot N, Misse D, Bonhomme F, Renaud F, Thomas F, Roche B.

BMC Cancer. 2015 Oct 24;15:792. doi: 10.1186/s12885-015-1782-z. Review.


Quantitative proteomic view associated with resistance to clinically important antibiotics in Gram-positive bacteria: a systematic review.

Lee CR, Lee JH, Park KS, Jeong BC, Lee SH.

Front Microbiol. 2015 Aug 11;6:828. doi: 10.3389/fmicb.2015.00828. eCollection 2015. Review.


DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cells.

Bose A, Pande P, Jasti VP, Millsap AD, Hawkins EK, Rizzo CJ, Basu AK.

Nucleic Acids Res. 2015 Sep 30;43(17):8340-51. doi: 10.1093/nar/gkv750. Epub 2015 Jul 28.


Evidence for the kinetic partitioning of polymerase activity on G-quadruplex DNA.

Eddy S, Maddukuri L, Ketkar A, Zafar MK, Henninger EE, Pursell ZF, Eoff RL.

Biochemistry. 2015 May 26;54(20):3218-30. doi: 10.1021/acs.biochem.5b00060. Epub 2015 May 11.


Fighting microbial drug resistance: a primer on the role of evolutionary biology in public health.

Perron GG, Inglis RF, Pennings PS, Cobey S.

Evol Appl. 2015 Mar;8(3):211-22. doi: 10.1111/eva.12254. Epub 2015 Mar 23.


A RecA protein surface required for activation of DNA polymerase V.

Gruber AJ, Erdem AL, Sabat G, Karata K, Jaszczur MM, Vo DD, Olsen TM, Woodgate R, Goodman MF, Cox MM.

PLoS Genet. 2015 Mar 26;11(3):e1005066. doi: 10.1371/journal.pgen.1005066. eCollection 2015 Mar.


An underlying mechanism for the increased mutagenesis of lagging-strand genes in Bacillus subtilis.

Million-Weaver S, Samadpour AN, Moreno-Habel DA, Nugent P, Brittnacher MJ, Weiss E, Hayden HS, Miller SI, Liachko I, Merrikh H.

Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):E1096-105. doi: 10.1073/pnas.1416651112. Epub 2015 Feb 23.


Replisome-mediated translesion synthesis and leading strand template lesion skipping are competing bypass mechanisms.

Gabbai CB, Yeeles JT, Marians KJ.

J Biol Chem. 2014 Nov 21;289(47):32811-23. doi: 10.1074/jbc.M114.613257. Epub 2014 Oct 9.


DNA polymerase η is regulated by poly(rC)-binding protein 1 via mRNA stability.

Ren C, Cho SJ, Jung YS, Chen X.

Biochem J. 2014 Dec 15;464(3):377-86. doi: 10.1042/BJ20141164.


Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differences.

Weerasooriya S, Jasti VP, Basu AK.

PLoS One. 2014 Sep 16;9(9):e107915. doi: 10.1371/journal.pone.0107915. eCollection 2014. Erratum in: PLoS One. 2014;9(10):e112506.


Elucidation of kinetic mechanisms of human translesion DNA polymerase κ using tryptophan mutants.

Zhao L, Pence MG, Eoff RL, Yuan S, Fercu CA, Guengerich FP.

FEBS J. 2014 Oct;281(19):4394-410. doi: 10.1111/febs.12947. Epub 2014 Aug 14.

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