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Items: 17

1.

Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain.

Deuis JR, Wingerd JS, Winter Z, Durek T, Dekan Z, Sousa SR, Zimmermann K, Hoffmann T, Weidner C, Nassar MA, Alewood PF, Lewis RJ, Vetter I.

Toxins (Basel). 2016 Mar 17;8(3). pii: E78. doi: 10.3390/toxins8030078.

2.

Human β-defensin 4 with non-native disulfide bridges exhibit antimicrobial activity.

Sharma H, Nagaraj R.

PLoS One. 2015 Mar 18;10(3):e0119525. doi: 10.1371/journal.pone.0119525.

3.

Systematic study of binding of μ-conotoxins to the sodium channel NaV1.4.

Mahdavi S, Kuyucak S.

Toxins (Basel). 2014 Dec 18;6(12):3454-70. doi: 10.3390/toxins6123454.

4.

Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activity.

Green BR, Bulaj G, Norton RS.

Future Med Chem. 2014 Oct;6(15):1677-98. doi: 10.4155/fmc.14.107. Review.

5.

Bioactive marine drugs and marine biomaterials for brain diseases.

Grosso C, Valentão P, Ferreres F, Andrade PB.

Mar Drugs. 2014 May 2;12(5):2539-89. doi: 10.3390/md12052539.

6.

Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin.

Deuis JR, Lim YL, Rodrigues de Sousa S, Lewis RJ, Alewood PF, Cabot PJ, Vetter I.

Neuro Oncol. 2014 Oct;16(10):1324-32. doi: 10.1093/neuonc/nou048.

7.

Mechanism of μ-conotoxin PIIIA binding to the voltage-gated Na+ channel NaV1.4.

Chen R, Robinson A, Chung SH.

PLoS One. 2014 Mar 27;9(3):e93267. doi: 10.1371/journal.pone.0093267.

8.

A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors.

Luo S, Zhangsun D, Schroeder CI, Zhu X, Hu Y, Wu Y, Weltzin MM, Eberhard S, Kaas Q, Craik DJ, McIntosh JM, Whiteaker P.

FASEB J. 2014 Apr;28(4):1842-53. doi: 10.1096/fj.13-244103.

9.

Mammalian neuronal sodium channel blocker μ-conotoxin BuIIIB has a structured N-terminus that influences potency.

Kuang Z, Zhang MM, Gupta K, Gajewiak J, Gulyas J, Balaram P, Rivier JE, Olivera BM, Yoshikami D, Bulaj G, Norton RS.

ACS Chem Biol. 2013;8(6):1344-51. doi: 10.1021/cb300674x.

10.

Conotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics?

Knapp O, McArthur JR, Adams DJ.

Toxins (Basel). 2012 Nov 8;4(11):1236-60. doi: 10.3390/toxins4111236. Review.

11.

Binding modes of μ-conotoxin to the bacterial sodium channel (NaVAb).

Chen R, Chung SH.

Biophys J. 2012 Feb 8;102(3):483-8. doi: 10.1016/j.bpj.2011.12.041.

12.

A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors.

Favreau P, Benoit E, Hocking HG, Carlier L, D' hoedt D, Leipold E, Markgraf R, Schlumberger S, Córdova MA, Gaertner H, Paolini-Bertrand M, Hartley O, Tytgat J, Heinemann SH, Bertrand D, Boelens R, Stöcklin R, Molgó J.

Br J Pharmacol. 2012 Jul;166(5):1654-68. doi: 10.1111/j.1476-5381.2012.01837.x.

13.

Biochemical characterization of kappaM-RIIIJ, a Kv1.2 channel blocker: evaluation of cardioprotective effects of kappaM-conotoxins.

Chen P, Dendorfer A, Finol-Urdaneta RK, Terlau H, Olivera BM.

J Biol Chem. 2010 May 14;285(20):14882-9. doi: 10.1074/jbc.M109.068486.

14.

The M-superfamily of conotoxins: a review.

Jacob RB, McDougal OM.

Cell Mol Life Sci. 2010 Jan;67(1):17-27. doi: 10.1007/s00018-009-0125-0. Review.

15.

Structurally minimized mu-conotoxin analogues as sodium channel blockers: implications for designing conopeptide-based therapeutics.

Han TS, Zhang MM, Walewska A, Gruszczynski P, Robertson CR, Cheatham TE 3rd, Yoshikami D, Olivera BM, Bulaj G.

ChemMedChem. 2009 Mar;4(3):406-14. doi: 10.1002/cmdc.200800292.

16.

NMR-based mapping of disulfide bridges in cysteine-rich peptides: application to the mu-conotoxin SxIIIA.

Walewska A, Skalicky JJ, Davis DR, Zhang MM, Lopez-Vera E, Watkins M, Han TS, Yoshikami D, Olivera BM, Bulaj G.

J Am Chem Soc. 2008 Oct 29;130(43):14280-6. doi: 10.1021/ja804303p.

17.

Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA.

Yao S, Zhang MM, Yoshikami D, Azam L, Olivera BM, Bulaj G, Norton RS.

Biochemistry. 2008 Oct 14;47(41):10940-9. doi: 10.1021/bi801010u.

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