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Items: 1 to 20 of 58

1.

Nupr1 Modulates Methamphetamine-Induced Dopaminergic Neuronal Apoptosis and Autophagy through CHOP-Trib3-Mediated Endoplasmic Reticulum Stress Signaling Pathway.

Xu X, Huang E, Tai Y, Zhao X, Chen X, Chen C, Chen R, Liu C, Lin Z, Wang H, Xie WB.

Front Mol Neurosci. 2017 Jun 26;10:203. doi: 10.3389/fnmol.2017.00203. eCollection 2017.

2.

Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.

Langley MR, Ghaisas S, Ay M, Luo J, Palanisamy BN, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG.

Neurotoxicology. 2017 Jun 19. pii: S0161-813X(17)30098-0. doi: 10.1016/j.neuro.2017.06.002. [Epub ahead of print]

PMID:
28595911
3.

Lanatoside C, a cardiac glycoside, acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells.

Chao MW, Chen TH, Huang HL, Chang YW, HuangFu WC, Lee YC, Teng CM, Pan SL.

Sci Rep. 2017 Apr 7;7:46134. doi: 10.1038/srep46134.

4.

Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease.

Ay M, Luo J, Langley M, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG.

J Neurochem. 2017 Jun;141(5):766-782. doi: 10.1111/jnc.14033. Epub 2017 May 9.

PMID:
28376279
5.

Redox dynamics of manganese as a mitochondrial life-death switch.

Smith MR, Fernandes J, Go YM, Jones DP.

Biochem Biophys Res Commun. 2017 Jan 15;482(3):388-398. doi: 10.1016/j.bbrc.2016.10.126. Epub 2017 Feb 3. Review.

6.

From the Cover: Manganese Stimulates Mitochondrial H2O2 Production in SH-SY5Y Human Neuroblastoma Cells Over Physiologic as well as Toxicologic Range.

Fernandes J, Hao L, Bijli KM, Chandler JD, Orr M, Hu X, Jones DP, Go YM.

Toxicol Sci. 2017 Jan;155(1):213-223. doi: 10.1093/toxsci/kfw196. Epub 2016 Oct 4.

7.

Potential Role of Epigenetic Mechanism in Manganese Induced Neurotoxicity.

Tarale P, Chakrabarti T, Sivanesan S, Naoghare P, Bafana A, Krishnamurthi K.

Biomed Res Int. 2016;2016:2548792. doi: 10.1155/2016/2548792. Epub 2016 May 26. Review.

8.

Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.

Gordon R, Singh N, Lawana V, Ghosh A, Harischandra DS, Jin H, Hogan C, Sarkar S, Rokad D, Panicker N, Anantharam V, Kanthasamy AG, Kanthasamy A.

Neurobiol Dis. 2016 Sep;93:96-114. doi: 10.1016/j.nbd.2016.04.008. Epub 2016 May 2.

9.

Metals and Neurodegeneration.

Chen P, Miah MR, Aschner M.

F1000Res. 2016 Mar 17;5. pii: F1000 Faculty Rev-366. doi: 10.12688/f1000research.7431.1. eCollection 2016. Review.

10.

Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease.

Panicker N, Saminathan H, Jin H, Neal M, Harischandra DS, Gordon R, Kanthasamy K, Lawana V, Sarkar S, Luo J, Anantharam V, Kanthasamy AG, Kanthasamy A.

J Neurosci. 2015 Jul 8;35(27):10058-77. doi: 10.1523/JNEUROSCI.0302-15.2015.

11.

Alterations in mitochondrial dynamics induced by tebufenpyrad and pyridaben in a dopaminergic neuronal cell culture model.

Charli A, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG.

Neurotoxicology. 2016 Mar;53:302-313. doi: 10.1016/j.neuro.2015.06.007. Epub 2015 Jul 2.

12.

Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease.

Jin H, Kanthasamy A, Harischandra DS, Kondru N, Ghosh A, Panicker N, Anantharam V, Rana A, Kanthasamy AG.

J Biol Chem. 2014 Dec 12;289(50):34743-67. doi: 10.1074/jbc.M114.576702. Epub 2014 Oct 23.

13.

Protein kinase D1 (PKD1) phosphorylation promotes dopaminergic neuronal survival during 6-OHDA-induced oxidative stress.

Asaithambi A, Ay M, Jin H, Gosh A, Anantharam V, Kanthasamy A, Kanthasamy AG.

PLoS One. 2014 May 7;9(5):e96947. doi: 10.1371/journal.pone.0096947. eCollection 2014.

14.

Role of proteolytic activation of protein kinase Cδ in the pathogenesis of prion disease.

Harischandra DS, Kondru N, Martin DP, Kanthasamy A, Jin H, Anantharam V, Kanthasamy AG.

Prion. 2014 Jan-Feb;8(1):143-53.

15.

PASS-predicted Vitex negundo activity: antioxidant and antiproliferative properties on human hepatoma cells--an in vitro study.

Kadir FA, Kassim NM, Abdulla MA, Yehye WA.

BMC Complement Altern Med. 2013 Dec 4;13:343. doi: 10.1186/1472-6882-13-343.

16.

Iron depletion increases manganese uptake and potentiates apoptosis through ER stress.

Seo YA, Li Y, Wessling-Resnick M.

Neurotoxicology. 2013 Sep;38:67-73. doi: 10.1016/j.neuro.2013.06.002. Epub 2013 Jun 10.

17.

Manganese toxicity in the central nervous system: the glutamine/glutamate-γ-aminobutyric acid cycle.

Sidoryk-Wegrzynowicz M, Aschner M.

J Intern Med. 2013 May;273(5):466-77. doi: 10.1111/joim.12040. Review.

18.

N-Acetyl Cysteine Protects against Methamphetamine-Induced Dopaminergic Neurodegeneration via Modulation of Redox Status and Autophagy in Dopaminergic Cells.

Chandramani Shivalingappa P, Jin H, Anantharam V, Kanthasamy A, Kanthasamy A.

Parkinsons Dis. 2012;2012:424285. doi: 10.1155/2012/424285. Epub 2012 Sep 27.

19.

Mechanism of Mn(II)-mediated dysregulation of glutamine-glutamate cycle: focus on glutamate turnover.

Sidoryk-Wegrzynowicz M, Lee E, Aschner M.

J Neurochem. 2012 Aug;122(4):856-67. doi: 10.1111/j.1471-4159.2012.07835.x. Epub 2012 Jul 9.

20.

Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation.

Gordon R, Anantharam V, Kanthasamy AG, Kanthasamy A.

J Neuroinflammation. 2012 Apr 27;9:82. doi: 10.1186/1742-2094-9-82.

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