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Spatiotemporal organization of cilia drives multiscale mucus swirls in model human bronchial epithelium.

Khelloufi MK, Loiseau E, Jaeger M, Molinari N, Chanez P, Gras D, Viallat A.

Sci Rep. 2018 Feb 5;8(1):2447. doi: 10.1038/s41598-018-20882-4.


ATP12A promotes mucus dysfunction during Type 2 airway inflammation.

Lennox AT, Coburn SL, Leech JA, Heidrich EM, Kleyman TR, Wenzel SE, Pilewski JM, Corcoran TE, Myerburg MM.

Sci Rep. 2018 Feb 1;8(1):2109. doi: 10.1038/s41598-018-20444-8.


Predictors of pneumonia on routine chest radiographs in patients with COPD: a post hoc analysis of two 1-year randomized controlled trials.

Rubin DB, Ahmad HA, O'Neal M, Bennett S, Lettis S, Galkin DV, Crim C.

Int J Chron Obstruct Pulmon Dis. 2018 Jan 8;13:189-201. doi: 10.2147/COPD.S142530. eCollection 2018.


Allergic Aspergillus Rhinosinusitis.

Chakrabarti A, Kaur H.

J Fungi (Basel). 2016 Dec 8;2(4). pii: E32. doi: 10.3390/jof2040032. Review.


Impaired PGE2-stimulated Cl- and HCO3- secretion contributes to cystic fibrosis airway disease.

Sellers ZM, Illek B, Figueira MF, Hari G, Joo NS, Sibley E, Souza-Menezes J, Morales MM, Fischer H, Wine JJ.

PLoS One. 2017 Dec 27;12(12):e0189894. doi: 10.1371/journal.pone.0189894. eCollection 2017.


Technological strategies to estimate and control diffusive passage times through the mucus barrier in mucosal drug delivery.

Newby JM, Seim I, Lysy M, Ling Y, Huckaby J, Lai SK, Forest MG.

Adv Drug Deliv Rev. 2018 Jan 15;124:64-81. doi: 10.1016/j.addr.2017.12.002. Epub 2017 Dec 12. Review.


Enhancement of lung gene delivery after aerosol: a new strategy using non-viral complexes with antibacterial properties.

Mottais A, Le Gall T, Sibiril Y, Ravel J, Laurent V, d'Arbonneau F, Montier T.

Biosci Rep. 2017 Nov 17;37(6). pii: BSR20160618. doi: 10.1042/BSR20160618. Print 2017 Dec 22. Review.


Cystic fibrosis swine fail to secrete airway surface liquid in response to inhalation of pathogens.

Luan X, Belev G, Tam JS, Jagadeeshan S, Hassan N, Gioino P, Grishchenko N, Huang Y, Carmalt JL, Duke T, Jones T, Monson B, Burmester M, Simovich T, Yilmaz O, Campanucci VA, Machen TE, Chapman LD, Ianowski JP.

Nat Commun. 2017 Oct 5;8(1):786. doi: 10.1038/s41467-017-00835-7.


Physicochemical properties of mucus and their impact on transmucosal drug delivery.

Leal J, Smyth HDC, Ghosh D.

Int J Pharm. 2017 Oct 30;532(1):555-572. doi: 10.1016/j.ijpharm.2017.09.018. Epub 2017 Sep 14. Review.


Role of Smad3 and p38 Signalling in Cigarette Smoke-induced CFTR and BK dysfunction in Primary Human Bronchial Airway Epithelial Cells.

Sailland J, Grosche A, Baumlin N, Dennis JS, Schmid A, Krick S, Salathe M.

Sci Rep. 2017 Sep 5;7(1):10506. doi: 10.1038/s41598-017-11038-x.


Mitochondrial toxicity of tobacco smoke and air pollution.

Fetterman JL, Sammy MJ, Ballinger SW.

Toxicology. 2017 Nov 1;391:18-33. doi: 10.1016/j.tox.2017.08.002. Epub 2017 Aug 22. Review. No abstract available.


Motile cilia create fluid-mechanical microhabitats for the active recruitment of the host microbiome.

Nawroth JC, Guo H, Koch E, Heath-Heckman EAC, Hermanson JC, Ruby EG, Dabiri JO, Kanso E, McFall-Ngai M.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):9510-9516. doi: 10.1073/pnas.1706926114. Epub 2017 Aug 23.


Overnight delivery of hypertonic saline by nasal cannula aerosol for cystic fibrosis.

Corcoran TE, Godovchik JE, Donn KH, Busick DR, Goralski J, Locke LW, Markovetz MR, Myerburg MM, Muthukrishnan A, Weber L, Lacy RT, Pilewski JM.

Pediatr Pulmonol. 2017 Sep;52(9):1142-1149. doi: 10.1002/ppul.23749. Epub 2017 Jul 24.


A new index for characterizing micro-bead motion in a flow induced by ciliary beating: Part I, experimental analysis.

Bottier M, Blanchon S, Pelle G, Bequignon E, Isabey D, Coste A, Escudier E, Grotberg JB, Papon JF, Filoche M, Louis B.

PLoS Comput Biol. 2017 Jul 14;13(7):e1005605. doi: 10.1371/journal.pcbi.1005605. eCollection 2017 Jul.


A new index for characterizing micro-bead motion in a flow induced by ciliary beating: Part II, modeling.

Bottier M, Peña Fernández M, Pelle G, Isabey D, Louis B, Grotberg JB, Filoche M.

PLoS Comput Biol. 2017 Jul 14;13(7):e1005552. doi: 10.1371/journal.pcbi.1005552. eCollection 2017 Jul.


Small Airway Absorption and Microdosimetry of Inhaled Corticosteroid Particles after Deposition.

Longest PW, Hindle M.

Pharm Res. 2017 Oct;34(10):2049-2065. doi: 10.1007/s11095-017-2210-7. Epub 2017 Jun 22.


SPX-101 Is a Promising and Novel Nebulized ENaC Inhibitor.

Lennox A, Myerburg MM.

Am J Respir Crit Care Med. 2017 Sep 15;196(6):671-672. doi: 10.1164/rccm.201705-0928ED. No abstract available.


Active microrheology determines scale-dependent material properties of Chaetopterus mucus.

Weigand WJ, Messmore A, Tu J, Morales-Sanz A, Blair DL, Deheyn DD, Urbach JS, Robertson-Anderson RM.

PLoS One. 2017 May 31;12(5):e0176732. doi: 10.1371/journal.pone.0176732. eCollection 2017.


Efficacy of Rhesus Theta-Defensin-1 in Experimental Models of Pseudomonas aeruginosa Lung Infection and Inflammation.

Bensman TJ, Jayne JG, Sun M, Kimura E, Meinert J, Wang JC, Schaal JB, Tran D, Rao AP, Akbari O, Selsted ME, Beringer PM.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00154-17. doi: 10.1128/AAC.00154-17. Print 2017 Aug.


Curcumin Inhibits NTHi-Induced MUC5AC Mucin Overproduction in Otitis Media via Upregulation of MAPK Phosphatase MKP-1.

Konduru AS, Matsuyama S, Lee BC, Komatsu K, Li JD.

Int J Inflam. 2017;2017:4525309. doi: 10.1155/2017/4525309. Epub 2017 Apr 12.

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