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Items: 1 to 20 of 107


The role of the NORE1A tumor suppressor in Oncogene-Induced Senescence.

Barnoud T, Schmidt ML, Donninger H, Clark GJ.

Cancer Lett. 2017 Aug 1;400:30-36. doi: 10.1016/j.canlet.2017.04.030. Epub 2017 Apr 26. Review.


Rassf Proteins as Modulators of Mst1 Kinase Activity.

Bitra A, Sistla S, Mariam J, Malvi H, Anand R.

Sci Rep. 2017 Mar 22;7:45020. doi: 10.1038/srep45020.


Nonstructural protein 5B promotes degradation of the NORE1A tumor suppressor to facilitate hepatitis C virus replication.

Arora P, Basu A, Schmidt ML, Clark GJ, Donninger H, Nichols DB, Calvisi DF, Kaushik-Basu N.

Hepatology. 2017 May;65(5):1462-1477. doi: 10.1002/hep.29049. Epub 2017 Mar 30.


MST1/MST2 Protein Kinases: Regulation and Physiologic Roles.

Galan JA, Avruch J.

Biochemistry. 2016 Oct 4;55(39):5507-5519. Epub 2016 Sep 26. Review.


Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM).

Margineanu A, Chan JJ, Kelly DJ, Warren SC, Flatters D, Kumar S, Katan M, Dunsby CW, French PM.

Sci Rep. 2016 Jun 24;6:28186. doi: 10.1038/srep28186.


The MST/Hippo Pathway and Cell Death: A Non-Canonical Affair.

Fallahi E, O'Driscoll NA, Matallanas D.

Genes (Basel). 2016 Jun 17;7(6). pii: E28. doi: 10.3390/genes7060028. Review.


Nore1a drives Ras to flick the P53 senescence switch.

Donninger H, Clark GJ.

Mol Cell Oncol. 2015 Jun 10;3(3):e1055050. doi: 10.1080/23723556.2015.1055050. eCollection 2016 May.


Ras signaling through RASSF proteins.

Donninger H, Schmidt ML, Mezzanotte J, Barnoud T, Clark GJ.

Semin Cell Dev Biol. 2016 Oct;58:86-95. doi: 10.1016/j.semcdb.2016.06.007. Epub 2016 Jun 8. Review.


RhBMP-2 Activates Hippo Signaling through RASSF1 in Esophageal Cancer Cells.

Kim SM, Ye S, Rah SY, Park BH, Wang H, Kim JR, Kim SH, Jang KY, Lee KB.

Sci Rep. 2016 May 27;6:26821. doi: 10.1038/srep26821.


Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation.

Meng F, Zhou R, Wu S, Zhang Q, Jin Q, Zhou Y, Plouffe SW, Liu S, Song H, Xia Z, Zhao B, Ye S, Feng XH, Guan KL, Zou J, Xu P.

Genes Dev. 2016 May 1;30(9):1086-100. doi: 10.1101/gad.277533.116. Epub 2016 Apr 28.


Proteomics Analysis Reveals Novel RASSF2 Interaction Partners.

Barnoud T, Wilkey DW, Merchant ML, Clark JA, Donninger H.

Cancers (Basel). 2016 Mar 16;8(3). pii: E37. doi: 10.3390/cancers8030037.


Analysis of Liver Tumor-Prone Mouse Models of the Hippo Kinase Scaffold Proteins RASSF1A and SAV1.

Zhang X, Guo C, Wu X, Li AX, Liu L, Tsark W, Dammann R, Shen H, Vonderfecht SL, Pfeifer GP.

Cancer Res. 2016 May 1;76(9):2824-35. doi: 10.1158/0008-5472.CAN-15-3010. Epub 2016 Mar 15.


Mechanisms of Hippo pathway regulation.

Meng Z, Moroishi T, Guan KL.

Genes Dev. 2016 Jan 1;30(1):1-17. doi: 10.1101/gad.274027.115. Review.


RASSF6; the Putative Tumor Suppressor of the RASSF Family.

Iwasa H, Jiang X, Hata Y.

Cancers (Basel). 2015 Dec 9;7(4):2415-26. doi: 10.3390/cancers7040899. Review.


Ras Regulates Rb via NORE1A.

Barnoud T, Donninger H, Clark GJ.

J Biol Chem. 2016 Feb 5;291(6):3114-23. doi: 10.1074/jbc.M115.697557. Epub 2015 Dec 16.


RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb.

Wang J, Hua W, Huang SK, Fan K, Takeshima L, Mao Y, Hoon DS.

Oncotarget. 2015 Oct 6;6(30):30165-77. doi: 10.18632/oncotarget.5030.


The hippo pathway in heart development, regeneration, and diseases.

Zhou Q, Li L, Zhao B, Guan KL.

Circ Res. 2015 Apr 10;116(8):1431-47. doi: 10.1161/CIRCRESAHA.116.303311. Review.


NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2.

Donninger H, Calvisi DF, Barnoud T, Clark J, Schmidt ML, Vos MD, Clark GJ.

J Cell Biol. 2015 Mar 16;208(6):777-89. doi: 10.1083/jcb.201408087.


Regulation of mammalian Ste20 (Mst) kinases.

Rawat SJ, Chernoff J.

Trends Biochem Sci. 2015 Mar;40(3):149-56. doi: 10.1016/j.tibs.2015.01.001. Epub 2015 Feb 6. Review.


Ras regulates SCF(β-TrCP) protein activity and specificity via its effector protein NORE1A.

Schmidt ML, Donninger H, Clark GJ.

J Biol Chem. 2014 Nov 7;289(45):31102-10. doi: 10.1074/jbc.M114.594283. Epub 2014 Sep 12.

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