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Items: 1 to 20 of 195


Molecular basis for the autonomous promotion of cell proliferation by angiogenin.

Hoang TT, Raines RT.

Nucleic Acids Res. 2017 Jan 25;45(2):818-831. doi: 10.1093/nar/gkw1192. Epub 2016 Dec 2.


Knockout of the Ribonuclease Inhibitor Gene Leaves Human Cells Vulnerable to Secretory Ribonucleases.

Thomas SP, Kim E, Kim JS, Raines RT.

Biochemistry. 2016 Nov 22;55(46):6359-6362. Epub 2016 Nov 8.


On the preservation of non-covalent protein complexes during electrospray ionization.

Chingin K, Barylyuk K, Chen H.

Philos Trans A Math Phys Eng Sci. 2016 Oct 28;374(2079). pii: 20150377. doi: 10.1098/rsta.2015.0377. Review.


Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.

Zhuang X, Lv M, Zhong Z, Zhang L, Jiang R, Chen J.

J Exp Clin Cancer Res. 2016 Aug 30;35(1):130. doi: 10.1186/s13046-016-0408-x.


Design Considerations for RNA Spherical Nucleic Acids (SNAs).

Barnaby SN, Perelman GA, Kohlstedt KL, Chinen AB, Schatz GC, Mirkin CA.

Bioconjug Chem. 2016 Sep 21;27(9):2124-31. doi: 10.1021/acs.bioconjchem.6b00350. Epub 2016 Aug 14.


Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation.

Liu YC, Fujimori DG, Weissman JS.

Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):E4015-24. doi: 10.1073/pnas.1608795113. Epub 2016 Jun 28.


Replacing a single atom accelerates the folding of a protein and increases its thermostability.

Arnold U, Raines RT.

Org Biomol Chem. 2016 Jul 12;14(28):6780-5. doi: 10.1039/c6ob00980h.


The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement.

Prats-Ejarque G, Arranz-Trullén J, Blanco JA, Pulido D, Nogués MV, Moussaoui M, Boix E.

Biochem J. 2016 Jun 1;473(11):1523-36. doi: 10.1042/BCJ20160245. Epub 2016 Mar 24.


Using NMR spectroscopy to elucidate the role of molecular motions in enzyme function.

Lisi GP, Loria JP.

Prog Nucl Magn Reson Spectrosc. 2016 Feb;92-93:1-17. doi: 10.1016/j.pnmrs.2015.11.001. Epub 2015 Dec 7. Review.


PGL germ granule assembly protein is a base-specific, single-stranded RNase.

Aoki ST, Kershner AM, Bingman CA, Wickens M, Kimble J.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1279-84. doi: 10.1073/pnas.1524400113. Epub 2016 Jan 19.


Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.

Gagné D, French RL, Narayanan C, Simonović M, Agarwal PK, Doucet N.

Structure. 2015 Dec 1;23(12):2256-66. doi: 10.1016/j.str.2015.10.011. Epub 2015 Nov 19.


Transition State Charge Stabilization and Acid-Base Catalysis of mRNA Cleavage by the Endoribonuclease RelE.

Dunican BF, Hiller DA, Strobel SA.

Biochemistry. 2015 Dec 1;54(47):7048-57. doi: 10.1021/acs.biochem.5b00866. Epub 2015 Nov 12.


Human Cancer Antigen Globo H Is a Cell-Surface Ligand for Human Ribonuclease 1.

Eller CH, Chao TY, Singarapu KK, Ouerfelli O, Yang G, Markley JL, Danishefsky SJ, Raines RT.

ACS Cent Sci. 2015 Jul 22;1(4):181-190. Epub 2015 Jul 13.


Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition.

Zhou J, Ueda K, Zhao J, Sparrow JR.

J Biol Chem. 2015 Nov 6;290(45):27215-27. doi: 10.1074/jbc.M115.680363. Epub 2015 Sep 22.


Transition State Features in the Hepatitis Delta Virus Ribozyme Reaction Revealed by Atomic Perturbations.

Koo SC, Lu J, Li NS, Leung E, Das SR, Harris ME, Piccirilli JA.

J Am Chem Soc. 2015 Jul 22;137(28):8973-82. doi: 10.1021/jacs.5b01189. Epub 2015 Jul 14.


Optimized diazo scaffold for protein esterification.

Mix KA, Raines RT.

Org Lett. 2015 May 15;17(10):2358-61. doi: 10.1021/acs.orglett.5b00840. Epub 2015 May 4.


Integration of kinetic isotope effect analyses to elucidate ribonuclease mechanism.

Harris ME, Piccirilli JA, York DM.

Biochim Biophys Acta. 2015 Nov;1854(11):1801-8. doi: 10.1016/j.bbapap.2015.04.022. Epub 2015 Apr 30. Review.


In vitro application of ribonucleases: comparison of the effects on mRNA and miRNA stability.

Aryani A, Denecke B.

BMC Res Notes. 2015 Apr 22;8:164. doi: 10.1186/s13104-015-1114-z.


A hybrid chimeric system for versatile and ultra-sensitive RNase detection.

Persano S, Vecchio G, Pompa PP.

Sci Rep. 2015 Apr 1;5:9558. doi: 10.1038/srep09558.


Improving cell-free protein synthesis through genome engineering of Escherichia coli lacking release factor 1.

Hong SH, Kwon YC, Martin RW, Des Soye BJ, de Paz AM, Swonger KN, Ntai I, Kelleher NL, Jewett MC.

Chembiochem. 2015 Mar 23;16(5):844-53. doi: 10.1002/cbic.201402708. Epub 2015 Mar 3.

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