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Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1.

Morris EJ, Kawamura E, Gillespie JA, Balgi A, Kannan N, Muller WJ, Roberge M, Dedhar S.

Nat Commun. 2017 May 5;8:15289. doi: 10.1038/ncomms15289.


Chromosomal Instability in Gastric Cancer Biology.

Maleki SS, Röcken C.

Neoplasia. 2017 May;19(5):412-420. doi: 10.1016/j.neo.2017.02.012. Epub 2017 Apr 18. Review.


Prognostic value of CA20, a score based on centrosome amplification-associated genes, in breast tumors.

Ogden A, Rida PC, Aneja R.

Sci Rep. 2017 Mar 21;7(1):262. doi: 10.1038/s41598-017-00363-w.


Aurora A kinase inhibition enhances oncolytic herpes virotherapy through cytotoxic synergy and innate cellular immune modulation.

Currier MA, Sprague L, Rizvi TA, Nartker B, Chen CY, Wang PY, Hutzen BJ, Franczek MR, Patel AV, Chaney KE, Streby KA, Ecsedy JA, Conner J, Ratner N, Cripe TP.

Oncotarget. 2017 Mar 14;8(11):17412-17427. doi: 10.18632/oncotarget.14885.


Cell cycle proteins as promising targets in cancer therapy.

Otto T, Sicinski P.

Nat Rev Cancer. 2017 Jan 27;17(2):93-115. doi: 10.1038/nrc.2016.138. Review.


Links between DNA Replication, Stem Cells and Cancer.

Vassilev A, DePamphilis ML.

Genes (Basel). 2017 Jan 25;8(2). pii: E45. doi: 10.3390/genes8020045. Review.


Heterogeneity in sarcoma cell lines reveals enhanced motility of tetraploid versus diploid cells.

Jemaà M, Abdallah S, Lledo G, Perrot G, Lesluyes T, Teyssier C, Roux P, van Dijk J, Chibon F, Abrieu A, Morin N.

Oncotarget. 2017 Mar 7;8(10):16669-16689. doi: 10.18632/oncotarget.14291.


Investigating cytokinesis failure as a strategy in cancer therapy.

McKenzie C, D'Avino PP.

Oncotarget. 2016 Dec 27;7(52):87323-87341. doi: 10.18632/oncotarget.13556.


Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases.

Sahni JM, Gayle SS, Bonk KL, Vite LC, Yori JL, Webb B, Ramos EK, Seachrist DD, Landis MD, Chang JC, Bradner JE, Keri RA.

J Biol Chem. 2016 Nov 4;291(45):23756-23768. Epub 2016 Sep 20.


HPV16 E6 upregulates Aurora A expression.

Guo Y, Ma J, Zheng Y, Li L, Gui X, Wang Q, Meng X, Shang H.

Oncol Lett. 2016 Aug;12(2):1387-1393. Epub 2016 Jun 27.


Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer.

Pitts TM, Bradshaw-Pierce EL, Bagby SM, Hyatt SL, Selby HM, Spreafico A, Tentler JJ, McPhillips K, Klauck PJ, Capasso A, Diamond JR, Davis SL, Tan AC, Arcaroli JJ, Purkey A, Messersmith WA, Ecsedy JA, Eckhardt SG.

Oncotarget. 2016 Aug 2;7(31):50290-50301. doi: 10.18632/oncotarget.10366.


Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway.

Duhamel S, Girondel C, Dorn JF, Tanguay PL, Voisin L, Smits R, Maddox PS, Meloche S.

Cell Cycle. 2016 Jun 17;15(12):1631-42. doi: 10.1080/15384101.2016.1183851. Epub 2016 May 6.


Essential role for a novel population of binucleated mammary epithelial cells in lactation.

Rios AC, Fu NY, Jamieson PR, Pal B, Whitehead L, Nicholas KR, Lindeman GJ, Visvader JE.

Nat Commun. 2016 Apr 22;7:11400. doi: 10.1038/ncomms11400.


Effect of Food on the Pharmacokinetics of the Investigational Aurora A Kinase Inhibitor Alisertib (MLN8237) in Patients with Advanced Solid Tumors.

Falchook GS, Zhou X, Venkatakrishnan K, Kurzrock R, Mahalingam D, Goldman JW, Jung J, Ullmann CD, Milch C, Rosen LS, Sarantopoulos J.

Drugs R D. 2016 Mar;16(1):45-52. doi: 10.1007/s40268-015-0114-8.


The interplay between centrosomes and the Hippo tumor suppressor pathway.

Bolgioni AF, Ganem NJ.

Chromosome Res. 2016 Jan;24(1):93-104. doi: 10.1007/s10577-015-9502-8. Review.


Opposing Effects of Inhibitors of Aurora-A and EGFR in Autosomal-Dominant Polycystic Kidney Disease.

Nikonova AS, Deneka AY, Eckman L, Kopp MC, Hensley HH, Egleston BL, Golemis EA.

Front Oncol. 2015 Oct 16;5:228. doi: 10.3389/fonc.2015.00228. eCollection 2015.


The Non-Canonical Role of Aurora-A in DNA Replication.

Tsunematsu T, Arakaki R, Yamada A, Ishimaru N, Kudo Y.

Front Oncol. 2015 Aug 25;5:187. doi: 10.3389/fonc.2015.00187. eCollection 2015. Review.


Aurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A Review.

Gavriilidis P, Giakoustidis A, Giakoustidis D.

J Clin Med Res. 2015 Oct;7(10):742-51. doi: 10.14740/jocmr2295w. Epub 2015 Aug 23. Review.


NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability.

Croessmann S, Wong HY, Zabransky DJ, Chu D, Mendonca J, Sharma A, Mohseni M, Rosen DM, Scharpf RB, Cidado J, Cochran RL, Parsons HA, Dalton WB, Erlanger B, Button B, Cravero K, Kyker-Snowman K, Beaver JA, Kachhap S, Hurley PJ, Lauring J, Park BH.

Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11583-8. doi: 10.1073/pnas.1503683112. Epub 2015 Aug 31.


Centrosome aberrations in human mammary epithelial cells driven by cooperative interactions between p16INK4a deficiency and telomere-dependent genotoxic stress.

Domínguez D, Feijoo P, Bernal A, Ercilla A, Agell N, Genescà A, Tusell L.

Oncotarget. 2015 Sep 29;6(29):28238-56. doi: 10.18632/oncotarget.4958.

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