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Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50.

Choudhary RK, Siddiqui MQ, Thapa PS, Gadewal N, Nachimuthu SK, Varma AK.

Sci Rep. 2017 Jun 20;7(1):3849. doi: 10.1038/s41598-017-03816-4.


Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.

Nieborowska-Skorska M, Sullivan K, Dasgupta Y, Podszywalow-Bartnicka P, Hoser G, Maifrede S, Martinez E, Di Marcantonio D, Bolton-Gillespie E, Cramer-Morales K, Lee J, Li M, Slupianek A, Gritsyuk D, Cerny-Reiterer S, Seferynska I, Stoklosa T, Bullinger L, Zhao H, Gorbunova V, Piwocka K, Valent P, Civin CI, Muschen M, Dick JE, Wang JC, Bhatia S, Bhatia R, Eppert K, Minden MD, Sykes SM, Skorski T.

J Clin Invest. 2017 Jun 1;127(6):2392-2406. doi: 10.1172/JCI90825. Epub 2017 May 8.


Efficacy, long-term toxicity, and mechanistic studies of gold nanorods photothermal therapy of cancer in xenograft mice.

Ali MR, Rahman MA, Wu Y, Han T, Peng X, Mackey MA, Wang D, Shin HJ, Chen ZG, Xiao H, Wu R, Tang Y, Shin DM, El-Sayed MA.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):E3110-E3118. doi: 10.1073/pnas.1619302114. Epub 2017 Mar 29.


Breast cancer and associated factors: a review.

Ataollahi MR, Sharifi J, Paknahad MR, Paknahad A.

J Med Life. 2015;8(Spec Iss 4):6-11. Review.


DNA damage response is hijacked by human papillomaviruses to complete their life cycle.

Hong SY.

J Zhejiang Univ Sci B. 2017 Mar.;18(3):215-232. doi: 10.1631/jzus.B1600306.


AG36 Inhibits Human Breast Cancer Cells Proliferation by Promotion of Apoptosis In vitro and In vivo.

Mu LH, Wang YN, Wang DX, Zhang J, Liu L, Dong XZ, Hu Y, Liu P.

Front Pharmacol. 2017 Jan 26;8:15. doi: 10.3389/fphar.2017.00015. eCollection 2017.


OGT restrains the expansion of DNA damage signaling.

Chen Q, Yu X.

Nucleic Acids Res. 2016 Nov 2;44(19):9266-9278. Epub 2016 Jul 25.


Increased chromosomal radiosensitivity in asymptomatic carriers of a heterozygous BRCA1 mutation.

Baert A, Depuydt J, Van Maerken T, Poppe B, Malfait F, Storm K, van den Ende J, Van Damme T, De Nobele S, Perletti G, De Leeneer K, Claes KB, Vral A.

Breast Cancer Res. 2016 May 17;18(1):52. doi: 10.1186/s13058-016-0709-1.


Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair.

Croglio MP, Haake JM, Ryan CP, Wang VS, Lapier J, Schlarbaum JP, Dayani Y, Artuso E, Prandi C, Koltai H, Agama K, Pommier Y, Chen Y, Tricoli L, LaRocque JR, Albanese C, Yarden RI.

Oncotarget. 2016 Mar 22;7(12):13984-4001. doi: 10.18632/oncotarget.7414.


Roles of DNA mutation in the coding region and DNA methylation in the 5' flanking region of BRCA1 in canine mammary tumors.

Qiu H, Lin D.

J Vet Med Sci. 2016 Jul 1;78(6):943-9. doi: 10.1292/jvms.15-0557. Epub 2016 Feb 18.


"DNA Binding Region" of BRCA1 Affects Genetic Stability through modulating the Intra-S-Phase Checkpoint.

Masuda T, Xu X, Dimitriadis EK, Lahusen T, Deng CX.

Int J Biol Sci. 2016 Jan 1;12(2):133-43. doi: 10.7150/ijbs.14242. eCollection 2016.


Hsp90: A New Player in DNA Repair?

Pennisi R, Ascenzi P, di Masi A.

Biomolecules. 2015 Oct 16;5(4):2589-618. doi: 10.3390/biom5042589. Review. Erratum in: Biomolecules. 2016 Oct 18;6(4):.


BRCA1 Is Required for Maintenance of Phospho-Chk1 and G2/M Arrest during DNA Cross-Link Repair in DT40 Cells.

Draga M, Madgett EB, Vandenberg CJ, du Plessis D, Kaufmann A, Werler P, Chakraborty P, Lowndes NF, Hiom K.

Mol Cell Biol. 2015 Nov;35(22):3829-40. doi: 10.1128/MCB.01497-14. Epub 2015 Aug 31.


A role for homologous recombination proteins in cell cycle regulation.

Kostyrko K, Bosshard S, Urban Z, Mermod N.

Cell Cycle. 2015;14(17):2853-61. doi: 10.1080/15384101.2015.1049784. Epub 2015 Jun 30.


Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response.

Al-Kaabi MM, Alshareeda AT, Jerjees DA, Muftah AA, Green AR, Alsubhi NH, Nolan CC, Chan S, Cornford E, Madhusudan S, Ellis IO, Rakha EA.

Br J Cancer. 2015 Mar 3;112(5):901-11. doi: 10.1038/bjc.2014.576. Epub 2015 Feb 17.


Integrating transcriptomics and proteomics to show that tanshinone IIA suppresses cell growth by blocking glucose metabolism in gastric cancer cells.

Lin LL, Hsia CR, Hsu CL, Huang HC, Juan HF.

BMC Genomics. 2015 Feb 5;16:41. doi: 10.1186/s12864-015-1230-0.


ISWI chromatin remodeling complexes in the DNA damage response.

Aydin ÖZ, Vermeulen W, Lans H.

Cell Cycle. 2014;13(19):3016-25. doi: 10.4161/15384101.2014.956551.


Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stem-like cells.

Pickholtz I, Saadyan S, Keshet GI, Wang VS, Cohen R, Bouwman P, Jonkers J, Byers SW, Papa MZ, Yarden RI.

Oncotarget. 2014 Dec 15;5(23):11827-46.


The protein phosphatase 2A inhibitor LB100 sensitizes ovarian carcinoma cells to cisplatin-mediated cytotoxicity.

Chang KE, Wei BR, Madigan JP, Hall MD, Simpson RM, Zhuang Z, Gottesman MM.

Mol Cancer Ther. 2015 Jan;14(1):90-100. doi: 10.1158/1535-7163.MCT-14-0496. Epub 2014 Nov 5.


Apoptosis and molecular targeting therapy in cancer.

Hassan M, Watari H, AbuAlmaaty A, Ohba Y, Sakuragi N.

Biomed Res Int. 2014;2014:150845. doi: 10.1155/2014/150845. Epub 2014 Jun 12. Review.

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