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Items: 1 to 20 of 43


Deubiquitination and Stabilization of PD-L1 by CSN5.

Lim SO, Li CW, Xia W, Cha JH, Chan LC, Wu Y, Chang SS, Lin WC, Hsu JM, Hsu YH, Kim T, Chang WC, Hsu JL, Yamaguchi H, Ding Q, Wang Y, Yang Y, Chen CH, Sahin AA, Yu D, Hortobagyi GN, Hung MC.

Cancer Cell. 2016 Dec 12;30(6):925-939. doi: 10.1016/j.ccell.2016.10.010. Epub 2016 Nov 17.


Signaling pathways regulating cartilage growth plate formation and activity.

Samsa WE, Zhou X, Zhou G.

Semin Cell Dev Biol. 2017 Feb;62:3-15. doi: 10.1016/j.semcdb.2016.07.008. Epub 2016 Jul 11. Review.


Down-regulation of hTERT and Cyclin D1 transcription via PI3K/Akt and TGF-β pathways in MCF-7 Cancer cells with PX-866 and Raloxifene.

Peek GW, Tollefsbol TO.

Exp Cell Res. 2016 May 15;344(1):95-102. doi: 10.1016/j.yexcr.2016.03.022. Epub 2016 Mar 23.


Reverse correlation of Jab1 and Smad4 in PANC-1 cells involved in the pathogenesis of pancreatic cancer.

Li J, Gu Z, Li S, Xiao Z, Sun K.

Int J Clin Exp Pathol. 2015 Aug 1;8(8):9279-85. eCollection 2015.


AMP-activated protein kinase (AMPK) activation inhibits nuclear translocation of Smad4 in mesangial cells and diabetic kidneys.

Zhao J, Miyamoto S, You YH, Sharma K.

Am J Physiol Renal Physiol. 2015 May 15;308(10):F1167-77. doi: 10.1152/ajprenal.00234.2014. Epub 2014 Nov 26.


Expression of bone morphogenetic protein 2, 4, and related components of the BMP signaling pathway in the mouse uterus during the estrous cycle.

Li Y, Wei QW, Feng JG, Xu ML, Huang RH, Shi FX.

J Zhejiang Univ Sci B. 2014 Jul;15(7):601-10. doi: 10.1631/jzus.B1300288.


Loss of jab1 in osteochondral progenitor cells severely impairs embryonic limb development in mice.

Bashur LA, Chen D, Chen Z, Liang B, Pardi R, Murakami S, Zhou G.

J Cell Physiol. 2014 Nov;229(11):1607-17. doi: 10.1002/jcp.24602.


Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes.

Yoon JH, Jung SM, Park SH, Kato M, Yamashita T, Lee IK, Sudo K, Nakae S, Han JS, Kim OH, Oh BC, Sumida T, Kuroda M, Ju JH, Jung KC, Park SH, Kim DK, Mamura M.

EMBO Mol Med. 2013 Nov;5(11):1720-39. doi: 10.1002/emmm.201302524. Epub 2013 Oct 11. Erratum in: EMBO Mol Med. 2014 May;6(5):703.


Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin.

Salazar VS, Zarkadis N, Huang L, Watkins M, Kading J, Bonar S, Norris J, Mbalaviele G, Civitelli R.

J Cell Sci. 2013 Dec 15;126(Pt 24):5598-609. doi: 10.1242/jcs.132233. Epub 2013 Oct 7.


Porcine JAB1 significantly enhances apoptosis induced by staurosporine.

Jiang P, Wang J, Kang Z, Li D, Zhang D.

Cell Death Dis. 2013 Oct 3;4:e823. doi: 10.1038/cddis.2013.357.


Characterization of a unique motif in LIM mineralization protein-1 that interacts with jun activation-domain-binding protein 1.

Sangadala S, Yoshioka K, Enyo Y, Liu Y, Titus L, Boden SD.

Mol Cell Biochem. 2014 Jan;385(1-2):145-57.


COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels.

Wang H, Dey D, Carrera I, Minond D, Bianchi E, Xu S, Lakshmana MK.

J Biol Chem. 2013 Sep 13;288(37):26668-77. doi: 10.1074/jbc.M113.476689. Epub 2013 Aug 7.


Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network.

Nicklas D, Saiz L.

J R Soc Interface. 2013 Jun 26;10(86):20130363. doi: 10.1098/rsif.2013.0363. Print 2013 Sep 6.


The transcriptional co-regulator Jab1 is crucial for chondrocyte differentiation in vivo.

Chen D, Bashur LA, Liang B, Panattoni M, Tamai K, Pardi R, Zhou G.

J Cell Sci. 2013 Jan 1;126(Pt 1):234-43. doi: 10.1242/jcs.113795. Epub 2012 Nov 30.


Targeting Jab1/CSN5 in nasopharyngeal carcinoma.

Pan Y, Claret FX.

Cancer Lett. 2012 Dec 30;326(2):155-60. doi: 10.1016/j.canlet.2012.07.033. Epub 2012 Aug 4. Review.


Post-translational regulation of TGF-β receptor and Smad signaling.

Xu P, Liu J, Derynck R.

FEBS Lett. 2012 Jul 4;586(14):1871-84. doi: 10.1016/j.febslet.2012.05.010. Epub 2012 May 19. Review.


Regulation of the human catalytic subunit of telomerase (hTERT).

Daniel M, Peek GW, Tollefsbol TO.

Gene. 2012 May 1;498(2):135-46. doi: 10.1016/j.gene.2012.01.095. Epub 2012 Feb 13. Review.


Key role for ubiquitin protein modification in TGFβ signal transduction.

De Boeck M, ten Dijke P.

Ups J Med Sci. 2012 May;117(2):153-65. doi: 10.3109/03009734.2012.654858. Epub 2012 Feb 15. Review.

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