Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 42


mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation.

Fitter S, Matthews MP, Martin SK, Xie J, Ooi SS, Walkley CR, Codrington JD, Ruegg MA, Hall MN, Proud CG, Gronthos S, Zannettino AC.

Mol Cell Biol. 2017 Mar 17;37(7). pii: e00668-16. doi: 10.1128/MCB.00668-16. Print 2017 Apr 1.


Heregulin-1ß and HER3 in hepatocellular carcinoma: status and regulation by insulin.

Buta C, Benabou E, Lequoy M, Régnault H, Wendum D, Meratbene F, Chettouh H, Aoudjehane L, Conti F, Chrétien Y, Scatton O, Rosmorduc O, Praz F, Fartoux L, Desbois-Mouthon C.

J Exp Clin Cancer Res. 2016 Aug 11;35(1):126. doi: 10.1186/s13046-016-0402-3. Erratum in: J Exp Clin Cancer Res. 2016;35(1):154.


Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.

Copps KD, Hançer NJ, Qiu W, White MF.

J Biol Chem. 2016 Apr 15;291(16):8602-17. doi: 10.1074/jbc.M116.714915. Epub 2016 Feb 4.


Protein phosphatase 4 (PP4) functions as a critical regulator in tumor necrosis factor (TNF)-α-induced hepatic insulin resistance.

Zhao H, Huang X, Jiao J, Zhang H, Liu J, Qin W, Meng X, Shen T, Lin Y, Chu J, Li J.

Sci Rep. 2015 Dec 15;5:18093. doi: 10.1038/srep18093.


The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins.

Hakuno F, Fukushima T, Yoneyama Y, Kamei H, Ozoe A, Yoshihara H, Yamanaka D, Shibano T, Sone-Yonezawa M, Yu BC, Chida K, Takahashi S.

Front Endocrinol (Lausanne). 2015 May 26;6:73. doi: 10.3389/fendo.2015.00073. eCollection 2015. Review.


Cell lysis-free quantum dot multicolor cellular imaging-based mechanism study for TNF-α-induced insulin resistance.

Kim MJ, Rangasamy S, Shim Y, Song JM.

J Nanobiotechnology. 2015 Jan 27;13:4. doi: 10.1186/s12951-015-0064-x.


High dietary lipid level is associated with persistent hyperglycaemia and downregulation of muscle Akt-mTOR pathway in Senegalese sole (Solea senegalensis).

Borges P, Valente LM, Véron V, Dias K, Panserat S, Médale F.

PLoS One. 2014 Jul 18;9(7):e102196. doi: 10.1371/journal.pone.0102196. eCollection 2014.


Host insulin stimulates Echinococcus multilocularis insulin signalling pathways and larval development.

Hemer S, Konrad C, Spiliotis M, Koziol U, Schaack D, Förster S, Gelmedin V, Stadelmann B, Dandekar T, Hemphill A, Brehm K.

BMC Biol. 2014 Jan 27;12:5. doi: 10.1186/1741-7007-12-5.


Signaling pathways controlling skeletal muscle mass.

Egerman MA, Glass DJ.

Crit Rev Biochem Mol Biol. 2014 Jan-Feb;49(1):59-68. doi: 10.3109/10409238.2013.857291. Epub 2013 Nov 18. Review.


Insulin concentration is critical in culturing human neural stem cells and neurons.

Rhee YH, Choi M, Lee HS, Park CH, Kim SM, Yi SH, Oh SM, Cha HJ, Chang MY, Lee SH.

Cell Death Dis. 2013 Aug 8;4:e766. doi: 10.1038/cddis.2013.295.


The role of the cullin-5 e3 ubiquitin ligase in the regulation of insulin receptor substrate-1.

Hu CZ, Sethi JK, Hagen T.

Biochem Res Int. 2012;2012:282648. doi: 10.1155/2012/282648. Epub 2012 Dec 9.


mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.

Kim SJ, DeStefano MA, Oh WJ, Wu CC, Vega-Cotto NM, Finlan M, Liu D, Su B, Jacinto E.

Mol Cell. 2012 Dec 28;48(6):875-87. doi: 10.1016/j.molcel.2012.09.029. Epub 2012 Nov 8.


Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination.

Xu X, Keshwani M, Meyer K, Sarikas A, Taylor S, Pan ZQ.

J Biol Chem. 2012 Nov 23;287(48):40758-66. doi: 10.1074/jbc.M112.405209. Epub 2012 Oct 8.


Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function.

Martins AR, Nachbar RT, Gorjao R, Vinolo MA, Festuccia WT, Lambertucci RH, Cury-Boaventura MF, Silveira LR, Curi R, Hirabara SM.

Lipids Health Dis. 2012 Feb 23;11:30. doi: 10.1186/1476-511X-11-30. Review.


Proteasome alterations during adipose differentiation and aging: links to impaired adipocyte differentiation and development of oxidative stress.

Dasuri K, Zhang L, Ebenezer P, Fernandez-Kim SO, Bruce-Keller AJ, Szweda LI, Keller JN.

Free Radic Biol Med. 2011 Nov 1;51(9):1727-35. doi: 10.1016/j.freeradbiomed.2011.08.001. Epub 2011 Aug 10.


Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome.

Jin X, Moskophidis D, Mivechi NF.

Cell Metab. 2011 Jul 6;14(1):91-103. doi: 10.1016/j.cmet.2011.03.025.


Impaired-inactivation of FoxO1 contributes to glucose-mediated increases in serum very low-density lipoprotein.

Wu K, Cappel D, Martinez M, Stafford JM.

Endocrinology. 2010 Aug;151(8):3566-76. doi: 10.1210/en.2010-0204. Epub 2010 May 25.


Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1.

Leng S, Zhang W, Zheng Y, Liberman Z, Rhodes CJ, Eldar-Finkelman H, Sun XJ.

J Endocrinol. 2010 Aug;206(2):171-81. doi: 10.1677/JOE-09-0456. Epub 2010 May 13.

Supplemental Content

Support Center