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Items: 1 to 20 of 170

1.

Dihydroartemisinin induces autophagy-dependent death in human tongue squamous cell carcinoma cells through DNA double-strand break-mediated oxidative stress.

Shi X, Wang L, Li X, Bai J, Li J, Li S, Wang Z, Zhou M.

Oncotarget. 2017 Jul 11;8(28):45981-45993. doi: 10.18632/oncotarget.17520.

2.

Prospects for the Use of ATR Inhibitors to Treat Cancer.

Wagner JM, Kaufmann SH.

Pharmaceuticals (Basel). 2010 Apr 28;3(5):1311-1334. Review.

3.

Human CDK18 promotes replication stress signaling and genome stability.

Barone G, Staples CJ, Ganesh A, Patterson KW, Bryne DP, Myers KN, Patil AA, Eyers CE, Maslen S, Skehel JM, Eyers PA, Collis SJ.

Nucleic Acids Res. 2016 Oct 14;44(18):8772-8785. Epub 2016 Jul 5.

4.

Direct Binding to Replication Protein A (RPA)-coated Single-stranded DNA Allows Recruitment of the ATR Activator TopBP1 to Sites of DNA Damage.

Acevedo J, Yan S, Michael WM.

J Biol Chem. 2016 Jun 17;291(25):13124-31. doi: 10.1074/jbc.M116.729194. Epub 2016 Apr 26.

5.

Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?

Tsai RY.

Cell Mol Life Sci. 2016 May;73(9):1803-23. doi: 10.1007/s00018-016-2152-y. Epub 2016 Feb 17. Review.

6.

TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint.

Awate S, De Benedetti A.

BMC Mol Biol. 2016 Feb 9;17:3. doi: 10.1186/s12867-016-0056-x.

7.

The Mechanism by Which MYCN Amplification Confers an Enhanced Sensitivity to a PCNA-Derived Cell Permeable Peptide in Neuroblastoma Cells.

Gu L, Chu P, Lingeman R, McDaniel H, Kechichian S, Hickey RJ, Liu Z, Yuan YC, Sandoval JA, Fields GB, Malkas LH.

EBioMedicine. 2015 Nov 10;2(12):1923-31. doi: 10.1016/j.ebiom.2015.11.016. eCollection 2015 Dec.

8.

CSB-PGBD3 Mutations Cause Premature Ovarian Failure.

Qin Y, Guo T, Li G, Tang TS, Zhao S, Jiao X, Gong J, Gao F, Guo C, Simpson JL, Chen ZJ.

PLoS Genet. 2015 Jul 28;11(7):e1005419. doi: 10.1371/journal.pgen.1005419. eCollection 2015 Jul.

9.

hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ.

Xu Y, Wu X, Her C.

J Biol Chem. 2015 Jul 24;290(30):18545-58. doi: 10.1074/jbc.M115.642884. Epub 2015 Jun 8.

10.

Association of the Rad9-Rad1-Hus1 checkpoint clamp with MYH DNA glycosylase and DNA.

Hwang BJ, Jin J, Gunther R, Madabushi A, Shi G, Wilson GM, Lu AL.

DNA Repair (Amst). 2015 Jul;31:80-90. doi: 10.1016/j.dnarep.2015.05.004. Epub 2015 May 16.

11.

The fork and the kinase: a DNA replication tale from a CHK1 perspective.

González Besteiro MA, Gottifredi V.

Mutat Res Rev Mutat Res. 2015 Jan-Mar;763:168-80. doi: 10.1016/j.mrrev.2014.10.003. Epub 2014 Oct 22. Review.

12.

Cell biology of mitotic recombination.

Lisby M, Rothstein R.

Cold Spring Harb Perspect Biol. 2015 Mar 2;7(3):a016535. doi: 10.1101/cshperspect.a016535. Review.

13.

Quantitative phosphoproteomics of the ataxia telangiectasia-mutated (ATM) and ataxia telangiectasia-mutated and rad3-related (ATR) dependent DNA damage response in Arabidopsis thaliana.

Roitinger E, Hofer M, Köcher T, Pichler P, Novatchkova M, Yang J, Schlögelhofer P, Mechtler K.

Mol Cell Proteomics. 2015 Mar;14(3):556-71. doi: 10.1074/mcp.M114.040352. Epub 2015 Jan 5.

14.

Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation.

Shi XL, Yang J, Mao N, Wu JH, Ren LF, Yang Y, Yin XL, Wei L, Li MY, Wang BN.

Acta Pharmacol Sin. 2015 Feb;36(2):252-8. doi: 10.1038/aps.2014.106. Epub 2014 Dec 29.

15.

HERC2-USP20 axis regulates DNA damage checkpoint through Claspin.

Yuan J, Luo K, Deng M, Li Y, Yin P, Gao B, Fang Y, Wu P, Liu T, Lou Z.

Nucleic Acids Res. 2014 Dec 1;42(21):13110-21. doi: 10.1093/nar/gku1034. Epub 2014 Oct 29.

16.

Replication stress by Py-Im polyamides induces a non-canonical ATR-dependent checkpoint response.

Martínez TF, Phillips JW, Karanja KK, Polaczek P, Wang CM, Li BC, Campbell JL, Dervan PB.

Nucleic Acids Res. 2014 Oct;42(18):11546-59. doi: 10.1093/nar/gku866. Epub 2014 Sep 23.

17.

Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation.

Agustina L, Hahm SH, Han SH, Tran AH, Chung JH, Park JH, Park JW, Han YS.

BMC Mol Biol. 2014 Aug 15;15:17. doi: 10.1186/1471-2199-15-17.

18.

SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway.

Wu CS, Ouyang J, Mori E, Nguyen HD, Maréchal A, Hallet A, Chen DJ, Zou L.

Genes Dev. 2014 Jul 1;28(13):1472-84. doi: 10.1101/gad.238535.114.

19.

The ATR signaling pathway is disabled during infection with the parvovirus minute virus of mice.

Adeyemi RO, Pintel DJ.

J Virol. 2014 Sep 1;88(17):10189-99. doi: 10.1128/JVI.01412-14. Epub 2014 Jun 25.

20.

PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.

Jarrett SG, Wolf Horrell EM, Christian PA, Vanover JC, Boulanger MC, Zou Y, D'Orazio JA.

Mol Cell. 2014 Jun 19;54(6):999-1011. doi: 10.1016/j.molcel.2014.05.030.

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