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Items: 1 to 20 of 23


KSHV reduces autophagy in THP-1 cells and in differentiating monocytes by decreasing CAST/calpastatin and ATG5 expression.

Santarelli R, Granato M, Pentassuglia G, Lacconi V, Gilardini Montani MS, Gonnella R, Tafani M, Torrisi MR, Faggioni A, Cirone M.

Autophagy. 2016 Dec;12(12):2311-2325. Epub 2016 Oct 7.


The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway.

Tang L, Pei H, Yang Y, Wang X, Wang T, Gao E, Li D, Yang Y, Yang D.

Sci Rep. 2016 Jul 25;6:29975. doi: 10.1038/srep29975.


A protease storm cleaves a cell-cell adhesion molecule in cancer: multiple proteases converge to regulate PTPmu in glioma cells.

Phillips-Mason PJ, Craig SE, Brady-Kalnay SM.

J Cell Biochem. 2014 Sep;115(9):1609-23. doi: 10.1002/jcb.24824.


A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation.

St-Pierre J, Ostergaard HL.

PLoS One. 2013 Jul 31;8(7):e71531. doi: 10.1371/journal.pone.0071531. Print 2013.


Elevated calpain activity in acute myelogenous leukemia correlates with decreased calpastatin expression.

Niapour M, Farr C, Minden M, Berger SA.

Blood Cancer J. 2012 Jan;2(1):e51. doi: 10.1038/bcj.2011.50. Epub 2012 Jan 13.


Clinical severity of β-thalassaemia/Hb E disease is associated with differential activities of the calpain-calpastatin proteolytic system.

Sukati S, Svasti S, Stifanese R, Averna M, Panutdaporn N, Penglong T, Melloni E, Fucharoen S, Katzenmeier G.

PLoS One. 2012;7(5):e37133. doi: 10.1371/journal.pone.0037133. Epub 2012 May 16.


Acute-phase protein α1-antitrypsin inhibits neutrophil calpain I and induces random migration.

Al-Omari M, Korenbaum E, Ballmaier M, Lehmann U, Jonigk D, Manstein DJ, Welte T, Mahadeva R, Janciauskiene S.

Mol Med. 2011 Sep-Oct;17(9-10):865-74. doi: 10.2119/molmed.2011.00089. Epub 2011 Apr 11.


Calpains as potential anti-cancer targets.

Leloup L, Wells A.

Expert Opin Ther Targets. 2011 Mar;15(3):309-23. doi: 10.1517/14728222.2011.553611. Epub 2011 Jan 19. Review.


Effects of the plasmid-encoded toxin of enteroaggregative Escherichia coli on focal adhesion complexes.

Cappello RE, Estrada-Gutierrez G, Irles C, Giono-Cerezo S, Bloch RJ, Nataro JP.

FEMS Immunol Med Microbiol. 2011 Apr;61(3):301-14. doi: 10.1111/j.1574-695X.2010.00776.x. Epub 2011 Feb 7.


Targeted deletion of Capn4 in cells of the chondrocyte lineage impairs chondrocyte proliferation and differentiation.

Kashiwagi A, Schipani E, Fein MJ, Greer PA, Shimada M.

Mol Cell Biol. 2010 Jun;30(11):2799-810. doi: 10.1128/MCB.00157-10. Epub 2010 Apr 5.


Regulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK).

Chan KT, Bennin DA, Huttenlocher A.

J Biol Chem. 2010 Apr 9;285(15):11418-26. doi: 10.1074/jbc.M109.090746. Epub 2010 Feb 11.


Calpain inhibitor SNJ-1945 attenuates events prior to angiogenesis in cultured human retinal endothelial cells.

Ma H, Tochigi A, Shearer TR, Azuma M.

J Ocul Pharmacol Ther. 2009 Oct;25(5):409-14. doi: 10.1089/jop.2009.0030.


In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation.

Shimada M, Greer PA, McMahon AP, Bouxsein ML, Schipani E.

J Biol Chem. 2008 Jul 25;283(30):21002-10. doi: 10.1074/jbc.M710354200. Epub 2008 May 30.


Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion.

Cortesio CL, Chan KT, Perrin BJ, Burton NO, Zhang S, Zhang ZY, Huttenlocher A.

J Cell Biol. 2008 Mar 10;180(5):957-71. doi: 10.1083/jcb.200708048.


TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain.

Su LT, Agapito MA, Li M, Simonson WT, Huttenlocher A, Habas R, Yue L, Runnels LW.

J Biol Chem. 2006 Apr 21;281(16):11260-70. Epub 2006 Jan 25.


m-Calpain is required for preimplantation embryonic development in mice.

Dutt P, Croall DE, Arthur JS, Veyra TD, Williams K, Elce JS, Greer PA.

BMC Dev Biol. 2006 Jan 24;6:3.


FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion.

Benlimame N, He Q, Jie S, Xiao D, Xu YJ, Loignon M, Schlaepfer DD, Alaoui-Jamali MA.

J Cell Biol. 2005 Nov 7;171(3):505-16.


SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling.

Westhoff MA, Serrels B, Fincham VJ, Frame MC, Carragher NO.

Mol Cell Biol. 2004 Sep;24(18):8113-33.

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