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Hyperglycemia-induced oxidative stress and heart disease-cardioprotective effects of rooibos flavonoids and phenylpyruvic acid-2-O-β-D-glucoside.

Dludla PV, Joubert E, Muller CJF, Louw J, Johnson R.

Nutr Metab (Lond). 2017 Jul 10;14:45. doi: 10.1186/s12986-017-0200-8. eCollection 2017. Review.


Cardioprotective potential of N-acetyl cysteine against hyperglycaemia-induced oxidative damage: a protocol for a systematic review.

Dludla PV, Nkambule BB, Dias SC, Johnson R.

Syst Rev. 2017 May 12;6(1):96. doi: 10.1186/s13643-017-0493-8.


Intramyocardial Injection of Recombinant Adeno-Associated Viral Vector Coexpressing PR39/Adrenomedullin Enhances Angiogenesis and Reduces Apoptosis in a Rat Myocardial Infarction Model.

An R, Xi C, Xu J, Liu Y, Zhang S, Wang Y, Hao Y, Sun L.

Oxid Med Cell Longev. 2017;2017:1271670. doi: 10.1155/2017/1271670. Epub 2017 Mar 2.


High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.

Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC.

Sci Transl Med. 2017 Feb 15;9(377). pii: eaaf2584. doi: 10.1126/scitranslmed.aaf2584.


PDE5 Inhibitor Tadalafil and Hydroxychloroquine Cotreatment Provides Synergistic Protection against Type 2 Diabetes and Myocardial Infarction in Mice.

Wang R, Xi L, Kukreja RC.

J Pharmacol Exp Ther. 2017 Apr;361(1):29-38. doi: 10.1124/jpet.116.239087. Epub 2017 Jan 25.


The effect of perioperative insulin treatment on cardiodepression in mild adiposity in mice.

Boly CA, Eringa EC, Bouwman RA, van den Akker RF, de Man FS, Schalij I, Loer SA, Boer C, van den Brom CE.

Cardiovasc Diabetol. 2016 Sep 20;15(1):135. doi: 10.1186/s12933-016-0453-y.


Impact of high-fat, low-carbohydrate diet on myocardial substrate oxidation, insulin sensitivity, and cardiac function after ischemia-reperfusion.

Liu J, Wang P, Douglas SL, Tate JM, Sham S, Lloyd SG.

Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H1-H10. doi: 10.1152/ajpheart.00809.2015. Epub 2016 May 6.


Mutual inhibition of insulin signaling and PHLPP-1 determines cardioprotective efficiency of Akt in aged heart.

Xing Y, Sun W, Wang Y, Gao F, Ma H.

Aging (Albany NY). 2016 May;8(5):873-88. doi: 10.18632/aging.100933.


Long-term insulin treatment restores cardioprotection induced by sufentanil postconditioning in diabetic rat heart.

Zhang Y, Zhang L, Gu E, Zhu B, Zhao X, Chen J.

Exp Biol Med (Maywood). 2016 Mar;241(6):650-7. doi: 10.1177/1535370215622706. Epub 2016 Jan 8.


Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury.

Chuang YC, Yang JL, Yang DI, Lin TK, Liou CW, Chen SD.

Int J Mol Sci. 2015 Nov 4;16(11):26406-16. doi: 10.3390/ijms161125963.


The cardioprotective compound cloxyquin uncouples mitochondria and induces autophagy.

Zhang J, Nadtochiy SM, Urciuoli WR, Brookes PS.

Am J Physiol Heart Circ Physiol. 2016 Jan 1;310(1):H29-38. doi: 10.1152/ajpheart.00926.2014. Epub 2015 Oct 30.


Insulin Protects Cardiac Myocytes from Doxorubicin Toxicity by Sp1-Mediated Transactivation of Survivin.

Lee BS, Oh J, Kang SK, Park S, Lee SH, Choi D, Chung JH, Chung YW, Kang SM.

PLoS One. 2015 Aug 13;10(8):e0135438. doi: 10.1371/journal.pone.0135438. eCollection 2015.


Hyperinsulinemic Normoglycemia Does Not Meaningfully Improve Myocardial Performance during Cardiac Surgery: A Randomized Trial.

Duncan AE, Kateby Kashy B, Sarwar S, Singh A, Stenina-Adognravi O, Christoffersen S, Alfirevic A, Sale S, Yang D, Thomas JD, Gillinov M, Sessler DI.

Anesthesiology. 2015 Aug;123(2):272-87. doi: 10.1097/ALN.0000000000000723.


Histone Deacetylases Exert Class-Specific Roles in Conditioning the Brain and Heart Against Acute Ischemic Injury.

Aune SE, Herr DJ, Kutz CJ, Menick DR.

Front Neurol. 2015 Jun 30;6:145. doi: 10.3389/fneur.2015.00145. eCollection 2015. Review.


PI3K Phosphorylation Is Linked to Improved Electrical Excitability in an In Vitro Engineered Heart Tissue Disease Model System.

Kana K, Song H, Laschinger C, Zandstra PW, Radisic M.

Tissue Eng Part A. 2015 Sep;21(17-18):2379-89. doi: 10.1089/ten.TEA.2014.0412. Epub 2015 Aug 7.


Toll-interacting protein contributes to mortality following myocardial infarction through promoting inflammation and apoptosis.

Wan N, Liu X, Zhang XJ, Zhao Y, Hu G, Wan F, Zhang R, Zhu X, Xia H, Li H.

Br J Pharmacol. 2015 Jul;172(13):3383-96. doi: 10.1111/bph.13130. Epub 2015 Apr 24.


Glucose and potassium derangements by glucose-insulin-potassium infusion in acute myocardial infarction.

van der Horst IC, Timmer JR, Ottervanger JP, Bilo HJ, Miedema K, Gans RO, de Boer MJ, Vogelzang M, Nijsten MW, Zijlstra F.

Neth Heart J. 2006 Mar;14(3):89-94.


Role of Endothelial Cells in Myocardial Ischemia-Reperfusion Injury.

Singhal AK, Symons JD, Boudina S, Jaishy B, Shiu YT.

Vasc Dis Prev. 2010;7:1-14.


Resolvin D1, a metabolite of omega-3 polyunsaturated fatty acid, decreases post-myocardial infarct depression.

Gilbert K, Bernier J, Godbout R, Rousseau G.

Mar Drugs. 2014 Nov 13;12(11):5396-407. doi: 10.3390/md12115396.

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