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Items: 1 to 20 of 252

1.

Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.

Leibman RS, Richardson MW, Ellebrecht CT, Maldini CR, Glover JA, Secreto AJ, Kulikovskaya I, Lacey SF, Akkina SR, Yi Y, Shaheen F, Wang J, Dufendach KA, Holmes MC, Collman RG, Payne AS, Riley JL.

PLoS Pathog. 2017 Oct 12;13(10):e1006613. doi: 10.1371/journal.ppat.1006613. eCollection 2017 Oct.

2.

Long-term follow up of human T-cell responses to conserved HIV-1 regions elicited by DNA/simian adenovirus/MVA vaccine regimens.

Moyo N, Borthwick NJ, Wee EG, Capucci S, Crook A, Dorrell L, Hanke T.

PLoS One. 2017 Jul 18;12(7):e0181382. doi: 10.1371/journal.pone.0181382. eCollection 2017.

3.

South African Breast Cancer and HIV Outcomes Study: Methods and Baseline Assessment.

Cubasch H, Ruff P, Joffe M, Norris S, Chirwa T, Nietz S, Sharma V, Duarte R, Buccimazza I, Čačala S, Stopforth LW, Tsai WY, Stavsky E, Crew KD, Jacobson JS, Neugut AI.

J Glob Oncol. 2017 Apr;3(2):114-124. doi: 10.1200/JGO.2015.002675.

4.

Conserved HIV-1 Gag p24 Epitopes Elicit Cellular Immune Responses That Impact Disease Outcome.

Tarosso LF, Vieira VA, Sauer MM, Tomiyama HI, Kalil J, Kallas EG.

AIDS Res Hum Retroviruses. 2017 Aug;33(8):832-842. doi: 10.1089/AID.2016.0168. Epub 2017 Aug 3.

PMID:
28594230
5.

T-Cell Receptor (TCR) Clonotype-Specific Differences in Inhibitory Activity of HIV-1 Cytotoxic T-Cell Clones Is Not Mediated by TCR Alone.

Flerin NC, Chen H, Glover TD, Lamothe PA, Zheng JH, Fang JW, Ndhlovu ZM, Newell EW, Davis MM, Walker BD, Goldstein H.

J Virol. 2017 Feb 28;91(6). pii: e02412-16. doi: 10.1128/JVI.02412-16. Print 2017 Mar 15.

6.

Large Variations in HIV-1 Viral Load Explained by Shifting-Mosaic Metapopulation Dynamics.

Lythgoe KA, Blanquart F, Pellis L, Fraser C.

PLoS Biol. 2016 Oct 5;14(10):e1002567. doi: 10.1371/journal.pbio.1002567. eCollection 2016 Oct.

7.

IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection.

Younes SA, Freeman ML, Mudd JC, Shive CL, Reynaldi A, Panigrahi S, Estes JD, Deleage C, Lucero C, Anderson J, Schacker TW, Davenport MP, McCune JM, Hunt PW, Lee SA, Serrano-Villar S, Debernardo RL, Jacobson JM, Canaday DH, Sekaly RP, Rodriguez B, Sieg SF, Lederman MM.

J Clin Invest. 2016 Jul 1;126(7):2745-56. doi: 10.1172/JCI85996. Epub 2016 Jun 20.

8.

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses.

Pulko V, Davies JS, Martinez C, Lanteri MC, Busch MP, Diamond MS, Knox K, Bush EC, Sims PA, Sinari S, Billheimer D, Haddad EK, Murray KO, Wertheimer AM, Nikolich-Žugich J.

Nat Immunol. 2016 Aug;17(8):966-75. doi: 10.1038/ni.3483. Epub 2016 Jun 6.

9.

Lower Viral Loads and Slower CD4+ T-Cell Count Decline in MRKAd5 HIV-1 Vaccinees Expressing Disease-Susceptible HLA-B*58:02.

Leitman EM, Hurst J, Mori M, Kublin J, Ndung'u T, Walker BD, Carlson J, Gray GE, Matthews PC, Frahm N, Goulder PJ.

J Infect Dis. 2016 Aug 1;214(3):379-89. doi: 10.1093/infdis/jiw093. Epub 2016 Mar 6.

10.

Elevation and persistence of CD8 T-cells in HIV infection: the Achilles heel in the ART era.

Cao W, Mehraj V, Kaufmann DE, Li T, Routy JP.

J Int AIDS Soc. 2016 Mar 3;19(1):20697. doi: 10.7448/IAS.19.1.20697. eCollection 2016. Review.

11.

An initial examination of the potential role of T-cell immunity in protection against feline immunodeficiency virus (FIV) infection.

Aranyos AM, Roff SR, Pu R, Owen JL, Coleman JK, Yamamoto JK.

Vaccine. 2016 Mar 14;34(12):1480-8. doi: 10.1016/j.vaccine.2016.01.017. Epub 2016 Jan 21.

12.

Dynamic Perturbations of the T-Cell Receptor Repertoire in Chronic HIV Infection and following Antiretroviral Therapy.

Heather JM, Best K, Oakes T, Gray ER, Roe JK, Thomas N, Friedman N, Noursadeghi M, Chain B.

Front Immunol. 2016 Jan 11;6:644. doi: 10.3389/fimmu.2015.00644. eCollection 2015.

13.

A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART.

Gómez CE, Perdiguero B, García-Arriaza J, Cepeda V, Sánchez-Sorzano CÓ, Mothe B, Jiménez JL, Muñoz-Fernández MÁ, Gatell JM, López Bernaldo de Quirós JC, Brander C, García F, Esteban M.

PLoS One. 2015 Nov 6;10(11):e0141456. doi: 10.1371/journal.pone.0141456. eCollection 2015.

14.

Expansion of Simian Immunodeficiency Virus (SIV)-Specific CD8 T Cell Lines from SIV-Naive Mauritian Cynomolgus Macaques for Adoptive Transfer.

Mohns MS, Greene JM, Cain BT, Pham NH, Gostick E, Price DA, O'Connor DH.

J Virol. 2015 Oct;89(19):9748-57. doi: 10.1128/JVI.00993-15. Epub 2015 Jul 15.

15.

CD8(+) T-cell Cytotoxic Capacity Associated with Human Immunodeficiency Virus-1 Control Can Be Mediated through Various Epitopes and Human Leukocyte Antigen Types.

Migueles SA, Mendoza D, Zimmerman MG, Martins KM, Toulmin SA, Kelly EP, Peterson BA, Johnson SA, Galson E, Poropatich KO, Patamawenu A, Imamichi H, Ober A, Rehm CA, Jones S, Hallahan CW, Follmann DA, Connors M.

EBioMedicine. 2014 Dec 22;2(1):46-58. doi: 10.1016/j.ebiom.2014.12.009. eCollection 2015 Jan.

16.

Head-to-Head Comparison of Poxvirus NYVAC and ALVAC Vectors Expressing Identical HIV-1 Clade C Immunogens in Prime-Boost Combination with Env Protein in Nonhuman Primates.

García-Arriaza J, Perdiguero B, Heeney J, Seaman M, Montefiori DC, Labranche C, Yates NL, Shen X, Tomaras GD, Ferrari G, Foulds KE, McDermott A, Kao SF, Roederer M, Hawkins N, Self S, Yao J, Farrell P, Phogat S, Tartaglia J, Barnett SW, Burke B, Cristillo A, Weiss D, Lee C, Kibler K, Jacobs B, Asbach B, Wagner R, Ding S, Pantaleo G, Esteban M.

J Virol. 2015 Aug;89(16):8525-39. doi: 10.1128/JVI.01265-15. Epub 2015 Jun 3.

17.

Engineering T Cells to Functionally Cure HIV-1 Infection.

Leibman RS, Riley JL.

Mol Ther. 2015 Jul;23(7):1149-1159. doi: 10.1038/mt.2015.70. Epub 2015 Apr 21. Review.

18.

Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers.

Pombo C, Wherry EJ, Gostick E, Price DA, Betts MR.

J Infect Dis. 2015 Nov 1;212(9):1376-86. doi: 10.1093/infdis/jiv226. Epub 2015 Apr 15.

19.

Clinical outcome of HIV viraemic controllers and noncontrollers with normal CD4 counts is exclusively determined by antigen-specific CD8+ T-cell-mediated HIV suppression.

Tansiri Y, Rowland-Jones SL, Ananworanich J, Hansasuta P.

PLoS One. 2015 Mar 12;10(3):e0118871. doi: 10.1371/journal.pone.0118871. eCollection 2015.

20.

Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options.

Velu V, Shetty RD, Larsson M, Shankar EM.

Retrovirology. 2015 Feb 8;12:14. doi: 10.1186/s12977-015-0144-x. Review.

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