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Items: 16


Piecemeal Buildup of the Genetic Code, Ribosomes, and Genomes from Primordial tRNA Building Blocks.

Caetano-Anollés D, Caetano-Anollés G.

Life (Basel). 2016 Dec 2;6(4). pii: E43.


Computing the origin and evolution of the ribosome from its structure - Uncovering processes of macromolecular accretion benefiting synthetic biology.

Caetano-Anollés G, Caetano-Anollés D.

Comput Struct Biotechnol J. 2015 Jul 26;13:427-47. doi: 10.1016/j.csbj.2015.07.003. Review.


Ribosomal accretion, apriorism and the phylogenetic method: a response to Petrov and Williams.

Caetano-Anollés D, Caetano-Anollés G.

Front Genet. 2015 Jun 2;6:194. doi: 10.3389/fgene.2015.00194.


Structural phylogenomics reveals gradual evolutionary replacement of abiotic chemistries by protein enzymes in purine metabolism.

Caetano-Anollés K, Caetano-Anollés G.

PLoS One. 2013;8(3):e59300. doi: 10.1371/journal.pone.0059300.


Querying pathways in protein interaction networks based on hidden Markov models.

Qian X, Sze SH, Yoon BJ.

J Comput Biol. 2009 Feb;16(2):145-57. doi: 10.1089/cmb.2008.02TT.


Network-based approaches for linking metabolism with environment.

Janga SC, Babu MM.

Genome Biol. 2008;9(11):239. doi: 10.1186/gb-2008-9-11-239. Review.


Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code.

Sun FJ, Caetano-Anollés G.

PLoS One. 2008 Jul 30;3(7):e2799. doi: 10.1371/journal.pone.0002799.


Evolutionary patterns in the sequence and structure of transfer RNA: early origins of archaea and viruses.

Sun FJ, Caetano-Anollés G.

PLoS Comput Biol. 2008 Mar 7;4(3):e1000018. doi: 10.1371/journal.pcbi.1000018.


Practical and theoretical advances in predicting the function of a protein by its phylogenetic distribution.

Kensche PR, van Noort V, Dutilh BE, Huynen MA.

J R Soc Interface. 2008 Feb 6;5(19):151-70. Review.


The origin of modern metabolic networks inferred from phylogenomic analysis of protein architecture.

Caetano-Anollés G, Kim HS, Mittenthal JE.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9358-63.


Pyrimethamine as a potential pharmacological chaperone for late-onset forms of GM2 gangliosidosis.

Maegawa GH, Tropak M, Buttner J, Stockley T, Kok F, Clarke JT, Mahuran DJ.

J Biol Chem. 2007 Mar 23;282(12):9150-61.


MANET: tracing evolution of protein architecture in metabolic networks.

Kim HS, Mittenthal JE, Caetano-Anollés G.

BMC Bioinformatics. 2006 Jul 19;7:351.


Comparative mapping of sequence-based and structure-based protein domains.

Zhang Y, Chandonia JM, Ding C, Holbrook SR.

BMC Bioinformatics. 2005 Mar 25;6:77.


Metabolic interdependence of obligate intracellular bacteria and their insect hosts.

Zientz E, Dandekar T, Gross R.

Microbiol Mol Biol Rev. 2004 Dec;68(4):745-70. Review.


Sequence-based prediction of protein domains.

Liu J, Rost B.

Nucleic Acids Res. 2004 Jul 7;32(12):3522-30.

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