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Items: 1 to 20 of 97


Aldosterone, SGK1, and ion channels in the kidney.

Valinsky WC, Touyz RM, Shrier A.

Clin Sci (Lond). 2018 Jan 19;132(2):173-183. doi: 10.1042/CS20171525. Print 2018 Jan 31. Review.


Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connection.

Hasna J, Hague F, Rodat-Despoix L, Geerts D, Leroy C, Tulasne D, Ouadid-Ahidouch H, Kischel P.

Cell Death Differ. 2018 Mar;25(4):691-705. doi: 10.1038/s41418-017-0007-1. Epub 2018 Jan 11.


Signaling Cascade Involved in Rapid Stimulation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by Dexamethasone.

Bossmann M, Ackermann BW, Thome UH, Laube M.

Int J Mol Sci. 2017 Aug 19;18(8). pii: E1807. doi: 10.3390/ijms18081807.


SGK1/Nedd4-2 signaling pathway regulates the activity of human organic anion transporters 3.

Wang H, You G.

Biopharm Drug Dispos. 2017 Nov;38(8):449-457. doi: 10.1002/bdd.2085. Epub 2017 Aug 22.


Aldosterone regulates a 5' variant sgk1 transcript via a shared hormone response element in the sgk1 5' regulatory region.

Raikwar NS, Thomas CP.

Physiol Rep. 2017 Apr;5(7). pii: e13221. doi: 10.14814/phy2.13221.


Renal Tubular Ubiquitin-Protein Ligase NEDD4-2 Is Required for Renal Adaptation during Long-Term Potassium Depletion.

Al-Qusairi L, Basquin D, Roy A, Rajaram RD, Maillard MP, Subramanya AR, Staub O.

J Am Soc Nephrol. 2017 Aug;28(8):2431-2442. doi: 10.1681/ASN.2016070732. Epub 2017 Mar 13.


Serum and Glucocorticoid Regulated Kinase 1 in Sodium Homeostasis.

Lou Y, Zhang F, Luo Y, Wang L, Huang S, Jin F.

Int J Mol Sci. 2016 Aug 10;17(8). pii: E1307. doi: 10.3390/ijms17081307. Review.


Aldosterone Upregulates Transient Receptor Potential Melastatin 7 (TRPM7).

Valinsky WC, Jolly A, Miquel P, Touyz RM, Shrier A.

J Biol Chem. 2016 Sep 16;291(38):20163-72. doi: 10.1074/jbc.M116.735175. Epub 2016 Jul 27.


Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).

Anta B, Martín-Rodríguez C, Gomis-Perez C, Calvo L, López-Benito S, Calderón-García AA, Vicente-García C, Villarroel Á, Arévalo JC.

J Biol Chem. 2016 Sep 2;291(36):19132-45. doi: 10.1074/jbc.M116.722637. Epub 2016 Jul 21.


Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.

Al-Qusairi L, Basquin D, Roy A, Stifanelli M, Rajaram RD, Debonneville A, Nita I, Maillard M, Loffing J, Subramanya AR, Staub O.

Am J Physiol Renal Physiol. 2016 Aug 1;311(2):F330-42. doi: 10.1152/ajprenal.00002.2016. Epub 2016 Mar 23.


SGK1 regulation by miR-466g in cortical collecting duct cells.

Jacobs ME, Kathpalia PP, Chen Y, Thomas SV, Noonan EJ, Pao AC.

Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1251-7. doi: 10.1152/ajprenal.00024.2016. Epub 2016 Feb 24.


Regulation of ENaC trafficking in rat kidney.

Frindt G, Gravotta D, Palmer LG.

J Gen Physiol. 2016 Mar;147(3):217-27. doi: 10.1085/jgp.201511533. Epub 2016 Feb 15.


Increased Epithelial Sodium Channel Activity Contributes to Hypertension Caused by Na+-HCO3- Cotransporter Electrogenic 2 Deficiency.

Wen D, Yuan Y, Warner PC, Wang B, Cornelius RJ, Wang-France J, Li H, Boettger T, Sansom SC.

Hypertension. 2015 Jul;66(1):68-74. doi: 10.1161/HYPERTENSIONAHA.115.05394. Epub 2015 May 4.


Glucocorticoids Distinctively Modulate the CFTR Channel with Possible Implications in Lung Development and Transition into Extrauterine Life.

Laube M, Bossmann M, Thome UH.

PLoS One. 2015 Apr 24;10(4):e0124833. doi: 10.1371/journal.pone.0124833. eCollection 2015.


Regulation of αENaC transcription.

Chen L, Zhang X, Zhang W.

Vitam Horm. 2015;98:101-35. doi: 10.1016/bs.vh.2014.12.004. Epub 2015 Feb 14. Review.


ENaC activity and expression is decreased in the lungs of protein kinase C-α knockout mice.

Eaton AF, Yue Q, Eaton DC, Bao HF.

Am J Physiol Lung Cell Mol Physiol. 2014 Sep 1;307(5):L374-85. doi: 10.1152/ajplung.00040.2014. Epub 2014 Jul 11.


The phosphorylation of endogenous Nedd4-2 In Na(+)-absorbing human airway epithelial cells.

Ismail NA, Baines DL, Wilson SM.

Eur J Pharmacol. 2014 Jun 5;732:32-42. doi: 10.1016/j.ejphar.2014.03.005. Epub 2014 Mar 18.


Glucocorticoids and renal Na+ transport: implications for hypertension and salt sensitivity.

Hunter RW, Ivy JR, Bailey MA.

J Physiol. 2014 Apr 15;592(8):1731-44. doi: 10.1113/jphysiol.2013.267609. Epub 2014 Feb 17. Review.


Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells.

Warnock DG, Kusche-Vihrog K, Tarjus A, Sheng S, Oberleithner H, Kleyman TR, Jaisser F.

Nat Rev Nephrol. 2014 Mar;10(3):146-57. doi: 10.1038/nrneph.2013.275. Epub 2014 Jan 14. Review.


A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein.

Andersen MN, Krzystanek K, Petersen F, Bomholtz SH, Olesen SP, Abriel H, Jespersen T, Rasmussen HB.

J Biol Chem. 2013 Dec 27;288(52):36841-54. doi: 10.1074/jbc.M113.525931. Epub 2013 Nov 8.

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