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iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-κB and p53.

Nakazawa H, Chang K, Shinozaki S, Yasukawa T, Ishimaru K, Yasuhara S, Yu YM, Martyn JA, Tompkins RG, Shimokado K, Kaneki M.

PLoS One. 2017 Jan 18;12(1):e0170391. doi: 10.1371/journal.pone.0170391.


Anticancer Effects of a New SIRT Inhibitor, MHY2256, against Human Breast Cancer MCF-7 Cells via Regulation of MDM2-p53 Binding.

Park EY, Woo Y, Kim SJ, Kim DH, Lee EK, De U, Kim KS, Lee J, Jung JH, Ha KT, Choi WS, Kim IS, Lee BM, Yoon S, Moon HR, Kim HS.

Int J Biol Sci. 2016 Dec 6;12(12):1555-1567.


Redox control of senescence and age-related disease.

Chandrasekaran A, Idelchik MD, Melendez JA.

Redox Biol. 2016 Nov 16;11:91-102. doi: 10.1016/j.redox.2016.11.005. [Epub ahead of print] Review.


The expression of SIRT1 in articular cartilage of patients with knee osteoarthritis and its correlation with disease severity.

Li Y, Xiao W, Wu P, Deng Z, Zeng C, Li H, Yang T, Lei G.

J Orthop Surg Res. 2016 Nov 18;11(1):144.


P66Shc-Induced MicroRNA-34a Causes Diabetic Endothelial Dysfunction by Downregulating Sirtuin1.

Li Q, Kim YR, Vikram A, Kumar S, Kassan M, Gabani M, Lee SK, Jacobs JS, Irani K.

Arterioscler Thromb Vasc Biol. 2016 Dec;36(12):2394-2403.


The multifaceted influence of histone deacetylases on DNA damage signalling and DNA repair.

Roos WP, Krumm A.

Nucleic Acids Res. 2016 Dec 1;44(21):10017-10030.


Sirtuin 1 Promotes Deacetylation of Oct4 and Maintenance of Naive Pluripotency.

Williams EO, Taylor AK, Bell EL, Lim R, Kim DM, Guarente L.

Cell Rep. 2016 Oct 11;17(3):809-820. doi: 10.1016/j.celrep.2016.09.046.


CCAR2 Is Required for Proliferation and Tumor Maintenance in Human Squamous Cell Carcinoma.

Best SA, Nwaobasi AN, Schmults CD, Ramsey MR.

J Invest Dermatol. 2017 Feb;137(2):506-512. doi: 10.1016/j.jid.2016.09.027.


Inactivation of Sirt1 in mouse livers protects against endotoxemic liver injury by acetylating and activating NF-κB.

Cui X, Chen Q, Dong Z, Xu L, Lu T, Li D, Zhang J, Zhang M, Xia Q.

Cell Death Dis. 2016 Oct 6;7(10):e2403. doi: 10.1038/cddis.2016.270.


miRNA regulation of Sirtuin-1 expression in human astrocytoma.

Romeo SG, Conti A, Polito F, Tomasello C, Barresi V, La Torre D, Cucinotta M, Angileri FF, Bartolotta M, Di Giorgio RM, Aguennouz M.

Oncol Lett. 2016 Oct;12(4):2992-2998.


Physiological and hypoxic oxygen concentration differentially regulates human c-Kit+ cardiac stem cell proliferation and migration.

Bellio MA, Rodrigues CO, Landin AM, Hatzistergos KE, Kuznetsov J, Florea V, Valasaki K, Khan A, Hare JM, Schulman IH.

Am J Physiol Heart Circ Physiol. 2016 Dec 1;311(6):H1509-H1519. doi: 10.1152/ajpheart.00449.2016.


Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome.

Kuwano Y, Nishida K, Akaike Y, Kurokawa K, Nishikawa T, Masuda K, Rokutan K.

Int J Mol Sci. 2016 Sep 27;17(10). pii: E1638. Review.


A potent and selective small molecule inhibitor of sirtuin 1 promotes differentiation of pluripotent P19 cells into functional neurons.

Kim BS, Lee CH, Chang GE, Cheong E, Shin I.

Sci Rep. 2016 Sep 29;6:34324. doi: 10.1038/srep34324.


Melatonin prevents acute kidney injury in severely burned rats via the activation of SIRT1.

Bai XZ, He T, Gao JX, Liu Y, Liu JQ, Han SC, Li Y, Shi JH, Han JT, Tao K, Xie ST, Wang HT, Hu DH.

Sci Rep. 2016 Sep 7;6:32199. doi: 10.1038/srep32199.


The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: In vitro and in vivo studies.

Carrasco-Pozo C, Tan KN, Reyes-Farias M, De La Jara N, Ngo ST, Garcia-Diaz DF, Llanos P, Cires MJ, Borges K.

Redox Biol. 2016 Oct;9:229-243. doi: 10.1016/j.redox.2016.08.007.


Circadian clocks and breast cancer.

Blakeman V, Williams JL, Meng QJ, Streuli CH.

Breast Cancer Res. 2016 Sep 2;18(1):89. doi: 10.1186/s13058-016-0743-z. Review.


Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds.

Bonkowski MS, Sinclair DA.

Nat Rev Mol Cell Biol. 2016 Nov;17(11):679-690. doi: 10.1038/nrm.2016.93. Review.


Mechanisms of transcription factor acetylation and consequences in hearts.

Thiagarajan D, Vedantham S, Ananthakrishnan R, Schmidt AM, Ramasamy R.

Biochim Biophys Acta. 2016 Dec;1862(12):2221-2231. doi: 10.1016/j.bbadis.2016.08.011. Review.


SIRT1 and Kidney Function.

Guan Y, Hao CM.

Kidney Dis (Basel). 2016 Mar;1(4):258-65. doi: 10.1159/000440967. Review.


High Glucose Induces Reactivation of Latent Kaposi's Sarcoma-Associated Herpesvirus.

Ye F, Zeng Y, Sha J, Jones T, Kuhne K, Wood C, Gao SJ.

J Virol. 2016 Aug 17. pii: JVI.01049-16. [Epub ahead of print]

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