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Items: 1 to 20 of 97

1.

WRN is recruited to damaged telomeres via its RQC domain and tankyrase1-mediated poly-ADP-ribosylation of TRF1.

Sun L, Nakajima S, Teng Y, Chen H, Yang L, Chen X, Gao B, Levine AS, Lan L.

Nucleic Acids Res. 2017 Apr 20;45(7):3844-3859. doi: 10.1093/nar/gkx065.

2.

Mechanistic and biological considerations of oxidatively damaged DNA for helicase-dependent pathways of nucleic acid metabolism.

Crouch JD, Brosh RM Jr.

Free Radic Biol Med. 2017 Jun;107:245-257. doi: 10.1016/j.freeradbiomed.2016.11.022. Epub 2016 Nov 22. Review.

PMID:
27884703
3.

The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation.

Li B, Reddy S, Comai L.

Mol Cell Biol. 2017 Jan 19;37(3). pii: e00560-16. doi: 10.1128/MCB.00560-16. Print 2017 Feb 1.

PMID:
27849570
4.

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.

Zhou L, Dai H, Wu J, Zhou M, Yuan H, Du J, Yang L, Wu X, Xu H, Hua Y, Xu J, Zheng L, Shen B.

FASEB J. 2017 Jan;31(1):132-147. doi: 10.1096/fj.201600631R. Epub 2016 Sep 30.

PMID:
27694478
5.

Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.

de Renty C, Ellis NA.

Ageing Res Rev. 2017 Jan;33:36-51. doi: 10.1016/j.arr.2016.05.010. Epub 2016 May 26. Review.

PMID:
27238185
6.

Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1.

Cheng IC, Chen BC, Shuai HH, Chien FC, Chen P, Hsieh TS.

PLoS Biol. 2016 Jan 11;14(1):e1002349. doi: 10.1371/journal.pbio.1002349. eCollection 2016 Jan.

7.

RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin.

Sami F, Lu X, Parvathaneni S, Roy R, Gary RK, Sharma S.

Biochem J. 2015 Jun 1;468(2):227-44. doi: 10.1042/BJ20141021.

8.

Characterization of the Caenorhabditis elegans HIM-6/BLM helicase: unwinding recombination intermediates.

Jung H, Lee JA, Choi S, Lee H, Ahn B.

PLoS One. 2014 Jul 18;9(7):e102402. doi: 10.1371/journal.pone.0102402. eCollection 2014.

9.

Acetylation of Werner syndrome protein (WRN): relationships with DNA damage, DNA replication and DNA metabolic activities.

Lozada E, Yi J, Luo J, Orren DK.

Biogerontology. 2014 Aug;15(4):347-66. doi: 10.1007/s10522-014-9506-3. Epub 2014 Jun 26.

10.

Telomerase protects werner syndrome lineage-specific stem cells from premature aging.

Cheung HH, Liu X, Canterel-Thouennon L, Li L, Edmonson C, Rennert OM.

Stem Cell Reports. 2014 Mar 27;2(4):534-46. doi: 10.1016/j.stemcr.2014.02.006. eCollection 2014 Apr 8.

11.

Human RecQ helicases in DNA repair, recombination, and replication.

Croteau DL, Popuri V, Opresko PL, Bohr VA.

Annu Rev Biochem. 2014;83:519-52. doi: 10.1146/annurev-biochem-060713-035428. Epub 2014 Mar 3. Review.

12.

Serines 440 and 467 in the Werner syndrome protein are phosphorylated by DNA-PK and affects its dynamics in response to DNA double strand breaks.

Kusumoto-Matsuo R, Ghosh D, Karmakar P, May A, Ramsden D, Bohr VA.

Aging (Albany NY). 2014 Jan;6(1):70-81.

13.

Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins.

Hegde ML, Hegde PM, Bellot LJ, Mandal SM, Hazra TK, Li GM, Boldogh I, Tomkinson AE, Mitra S.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):E3090-9. doi: 10.1073/pnas.1304231110. Epub 2013 Jul 29.

14.

DNA helicases involved in DNA repair and their roles in cancer.

Brosh RM Jr.

Nat Rev Cancer. 2013 Aug;13(8):542-58. doi: 10.1038/nrc3560. Epub 2013 Jul 11. Review.

15.

Chromatin remodeling, DNA damage repair and aging.

Liu B, Yip RKh, Zhou Z.

Curr Genomics. 2012 Nov;13(7):533-47. doi: 10.2174/138920212803251373.

16.

Functional deficit associated with a missense Werner syndrome mutation.

Tadokoro T, Rybanska-Spaeder I, Kulikowicz T, Dawut L, Oshima J, Croteau DL, Bohr VA.

DNA Repair (Amst). 2013 Jun 1;12(6):414-21. doi: 10.1016/j.dnarep.2013.03.004. Epub 2013 Apr 11.

17.

Flap endonuclease 1.

Balakrishnan L, Bambara RA.

Annu Rev Biochem. 2013;82:119-38. doi: 10.1146/annurev-biochem-072511-122603. Epub 2013 Feb 28. Review.

18.

Human RECQL5 participates in the removal of endogenous DNA damage.

Tadokoro T, Ramamoorthy M, Popuri V, May A, Tian J, Sykora P, Rybanska I, Wilson DM 3rd, Croteau DL, Bohr VA.

Mol Biol Cell. 2012 Nov;23(21):4273-85. doi: 10.1091/mbc.E12-02-0110. Epub 2012 Sep 12.

19.

Regulation of chromatin structure by poly(ADP-ribosyl)ation.

Beneke S.

Front Genet. 2012 Sep 3;3:169. doi: 10.3389/fgene.2012.00169. eCollection 2012.

20.

The wonders of flap endonucleases: structure, function, mechanism and regulation.

Finger LD, Atack JM, Tsutakawa S, Classen S, Tainer J, Grasby J, Shen B.

Subcell Biochem. 2012;62:301-26. doi: 10.1007/978-94-007-4572-8_16. Review.

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