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Items: 7


Potent efficacy signals from systemically administered oncolytic herpes simplex virus (HSV1716) in hepatocellular carcinoma xenograft models.

Braidwood L, Learmonth K, Graham A, Conner J.

J Hepatocell Carcinoma. 2014 Oct 16;1:149-61. doi: 10.2147/JHC.S71019. eCollection 2014.


Immunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy.

Workenhe ST, Simmons G, Pol JG, Lichty BD, Halford WP, Mossman KL.

Mol Ther. 2014 Jan;22(1):123-31. doi: 10.1038/mt.2013.238. Epub 2013 Oct 9.


Targeting HSV-1 virions for specific binding to epidermal growth factor receptor-vIII-bearing tumor cells.

Grandi P, Fernandez J, Szentirmai O, Carter R, Gianni D, Sena-Esteves M, Breakefield XO.

Cancer Gene Ther. 2010 Sep;17(9):655-63. doi: 10.1038/cgt.2010.22. Epub 2010 May 28.


Phase I/II study of oncolytic herpes simplex virus NV1020 in patients with extensively pretreated refractory colorectal cancer metastatic to the liver.

Geevarghese SK, Geller DA, de Haan HA, Hörer M, Knoll AE, Mescheder A, Nemunaitis J, Reid TR, Sze DY, Tanabe KK, Tawfik H.

Hum Gene Ther. 2010 Sep;21(9):1119-28. doi: 10.1089/hum.2010.020.


Effects of herpes simplex virus amplicon transduction on murine dendritic cells.

Chiu YG, Bowers WJ, Lim ST, Ryan DA, Federoff HJ.

Hum Gene Ther. 2009 May;20(5):442-52. doi: 10.1089/hum.2008.160.


A herpes oncolytic virus can be delivered via the vasculature to produce biologic changes in human colorectal cancer.

Fong Y, Kim T, Bhargava A, Schwartz L, Brown K, Brody L, Covey A, Karrasch M, Getrajdman G, Mescheder A, Jarnagin W, Kemeny N.

Mol Ther. 2009 Feb;17(2):389-94. doi: 10.1038/mt.2008.240. Epub 2008 Nov 18.


Imaging and therapy of malignant pleural mesothelioma using replication-competent herpes simplex viruses.

Adusumilli PS, Stiles BM, Chan MK, Mullerad M, Eisenberg DP, Ben-Porat L, Huq R, Rusch VW, Fong Y.

J Gene Med. 2006 May;8(5):603-15.

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