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Items: 1 to 20 of 88


The Central Role of Amino Acids in Cancer Redox Homeostasis: Vulnerability Points of the Cancer Redox Code.

Vučetić M, Cormerais Y, Parks SK, Pouysségur J.

Front Oncol. 2017 Dec 21;7:319. doi: 10.3389/fonc.2017.00319. eCollection 2017. Review.


Evaluation of the cytotoxicity of the Bithionol-paclitaxel combination in a panel of human ovarian cancer cell lines.

Ayyagari VN, Diaz-Sylvester PL, Hsieh TJ, Brard L.

PLoS One. 2017 Sep 20;12(9):e0185111. doi: 10.1371/journal.pone.0185111. eCollection 2017.


Bystander signaling via oxidative metabolism.

Sawal HA, Asghar K, Bureik M, Jalal N.

Onco Targets Ther. 2017 Aug 4;10:3925-3940. doi: 10.2147/OTT.S136076. eCollection 2017. Review.


Redox Imbalance in the Development of Colorectal Cancer.

Liu H, Liu X, Zhang C, Zhu H, Xu Q, Bu Y, Lei Y.

J Cancer. 2017 Jun 3;8(9):1586-1597. doi: 10.7150/jca.18735. eCollection 2017. Review.


Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2.

Zhang Y, Qian Y, Zhang J, Yan W, Jung YS, Chen M, Huang E, Lloyd K, Duan Y, Wang J, Liu G, Chen X.

Genes Dev. 2017 Jul 26. doi: 10.1101/gad.299388.117. [Epub ahead of print]


The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells.

Dabiri Y, Kalman S, Gürth CM, Kim JY, Mayer V, Cheng X.

Sci Rep. 2017 Jul 14;7(1):5423. doi: 10.1038/s41598-017-05813-z.


Knockdown of PRDX2 sensitizes colon cancer cells to 5-FU by suppressing the PI3K/AKT signaling pathway.

Xu J, Zhang S, Wang R, Wu X, Zeng L, Fu Z.

Biosci Rep. 2017 May 11;37(3). pii: BSR20160447. doi: 10.1042/BSR20160447. Print 2017 Jun 30.


Antitumor effects of oncolytic herpes simplex virus type 2 against colorectal cancer in vitro and in vivo.

Yin L, Zhao C, Han J, Li Z, Zhen Y, Xiao R, Xu Z, Sun Y.

Ther Clin Risk Manag. 2017 Feb 7;13:117-130. doi: 10.2147/TCRM.S128575. eCollection 2017.


Brother of Regulator of Imprinted Sites (BORIS) suppresses apoptosis in colorectal cancer.

Zhang Y, Fang M, Song Y, Ren J, Fang J, Wang X.

Sci Rep. 2017 Jan 18;7:40786. doi: 10.1038/srep40786.


Evaluation of the cytotoxicity of the Bithionol - cisplatin combination in a panel of human ovarian cancer cell lines.

Ayyagari VN, Hsieh TJ, Diaz-Sylvester PL, Brard L.

BMC Cancer. 2017 Jan 13;17(1):49. doi: 10.1186/s12885-016-3034-2.


Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation in vitro and in mice.

Sommer J, Mahli A, Freese K, Schiergens TS, Kuecuekoktay FS, Teufel A, Thasler WE, Müller M, Bosserhoff AK, Hellerbrand C.

Oncotarget. 2017 Feb 21;8(8):13059-13072. doi: 10.18632/oncotarget.14371.


High-Resolution 4C Reveals Rapid p53-Dependent Chromatin Reorganization of the CDKN1A Locus in Response to Stress.

Millau JF, Wijchers P, Gaudreau L.

PLoS One. 2016 Oct 14;11(10):e0163885. doi: 10.1371/journal.pone.0163885. eCollection 2016.


Dual role of macrophages in the response of C26 colon carcinoma cells to 5-fluorouracil administration.

Patras L, Sesarman A, Licarete E, Luca L, Alupei MC, Rakosy-Tican E, Banciu M.

Oncol Lett. 2016 Aug;12(2):1183-1191. Epub 2016 Jun 13.


EglN2 positively regulates mitochondrial function in breast cancer.

Zhang J, Zheng X, Zhang Q.

Mol Cell Oncol. 2015 Dec 22;3(2):e1120845. doi: 10.1080/23723556.2015.1120845. eCollection 2016 Mar.


Enhancement of anti-tumor effects of 5-fluorouracil on hepatocellular carcinoma by low-intensity ultrasound.

Hu Z, Lv G, Li Y, Li E, Li H, Zhou Q, Yang B, Cao W.

J Exp Clin Cancer Res. 2016 Apr 22;35:71. doi: 10.1186/s13046-016-0349-4.


TP53 mutation, mitochondria and cancer.

Kamp WM, Wang PY, Hwang PM.

Curr Opin Genet Dev. 2016 Jun;38:16-22. doi: 10.1016/j.gde.2016.02.007. Epub 2016 Mar 19. Review.


Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.

Yin X, Manczak M, Reddy PH.

Hum Mol Genet. 2016 May 1;25(9):1739-53. doi: 10.1093/hmg/ddw045. Epub 2016 Feb 16.


microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis.

Zhang C, Liu J, Tan C, Yue X, Zhao Y, Peng J, Wang X, Laddha SV, Chan CS, Zheng S, Hu W, Feng Z.

Oncotarget. 2016 Feb 23;7(8):8783-96. doi: 10.18632/oncotarget.7088.


Innovative Target Therapies Are Able to Block the Inflammation Associated with Dysfunction of the Cholesterol Biosynthesis Pathway.

Marcuzzi A, Piscianz E, Loganes C, Vecchi Brumatti L, Knowles A, Bilel S, Tommasini A, Bortul R, Zweyer M.

Int J Mol Sci. 2015 Dec 30;17(1). pii: E47. doi: 10.3390/ijms17010047. Review.


Network Analysis Identifies Mitochondrial Regulation of Epidermal Differentiation by MPZL3 and FDXR.

Bhaduri A, Ungewickell A, Boxer LD, Lopez-Pajares V, Zarnegar BJ, Khavari PA.

Dev Cell. 2015 Nov 23;35(4):444-57. doi: 10.1016/j.devcel.2015.10.023.

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