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Items: 1 to 20 of 39

1.

The RNA-binding protein Tristetraprolin (TTP) is a critical negative regulator of the NLRP3 inflammasome.

Haneklaus M, O'Neil JD, Clark AR, Masters SL, O'Neill LAJ.

J Biol Chem. 2017 Apr 28;292(17):6869-6881. doi: 10.1074/jbc.M116.772947. Epub 2017 Mar 16.

PMID:
28302726
2.

Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo.

O'Neil JD, Ross EA, Ridley ML, Ding Q, Tang T, Rosner DR, Crowley T, Malhi D, Dean JL, Smallie T, Buckley CD, Clark AR.

Mol Cell Biol. 2017 May 16;37(11). pii: e00536-16. doi: 10.1128/MCB.00536-16. Print 2017 Jun 1.

3.

An Ancient Family of RNA-Binding Proteins: Still Important!

Wells ML, Perera L, Blackshear PJ.

Trends Biochem Sci. 2017 Apr;42(4):285-296. doi: 10.1016/j.tibs.2016.12.003. Epub 2017 Jan 14. Review.

PMID:
28096055
4.

Tristetraprolin as a Therapeutic Target in Inflammatory Disease.

Patial S, Blackshear PJ.

Trends Pharmacol Sci. 2016 Oct;37(10):811-21. doi: 10.1016/j.tips.2016.07.002. Epub 2016 Aug 5. Review.

PMID:
27503556
5.

RNA-binding proteins related to stress response and differentiation in protozoa.

Alves LR, Goldenberg S.

World J Biol Chem. 2016 Feb 26;7(1):78-87. doi: 10.4331/wjbc.v7.i1.78. Review.

6.

Effects of Combined Tristetraprolin/Tumor Necrosis Factor Receptor Deficiency on the Splenic Transcriptome.

Patial S, Stumpo DJ, Young WS 3rd, Ward JM, Flake GP, Blackshear PJ.

Mol Cell Biol. 2016 Apr 15;36(9):1395-411. doi: 10.1128/MCB.01068-15. Print 2016 May.

7.

Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism.

Stumpo DJ, Trempus CS, Tucker CJ, Huang W, Li L, Kluckman K, Bortner DM, Blackshear PJ.

Development. 2016 Apr 15;143(8):1424-33. doi: 10.1242/dev.130369. Epub 2016 Mar 7.

8.

RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes.

McDermott BT, Ellis S, Bou-Gharios G, Clegg PD, Tew SR.

Osteoarthritis Cartilage. 2016 Jul;24(7):1263-73. doi: 10.1016/j.joca.2016.01.988. Epub 2016 Feb 4.

9.

Enhanced stability of tristetraprolin mRNA protects mice against immune-mediated inflammatory pathologies.

Patial S, Curtis AD 2nd, Lai WS, Stumpo DJ, Hill GD, Flake GP, Mannie MD, Blackshear PJ.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1865-70. doi: 10.1073/pnas.1519906113. Epub 2016 Feb 1.

10.

ZFP36 stabilizes RIP1 via degradation of XIAP and cIAP2 thereby promoting ripoptosome assembly.

Selmi T, Alecci C, dell' Aquila M, Montorsi L, Martello A, Guizzetti F, Volpi N, Parenti S, Ferrari S, Salomoni P, Grande A, Zanocco-Marani T.

BMC Cancer. 2015 May 6;15:357. doi: 10.1186/s12885-015-1388-5.

11.

Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli.

Qiu LQ, Lai WS, Bradbury A, Zeldin DC, Blackshear PJ.

J Leukoc Biol. 2015 Apr;97(4):723-36. doi: 10.1189/jlb.3A0214-106R. Epub 2015 Feb 5.

12.

Myeloid ZFP36L1 does not regulate inflammation or host defense in mouse models of acute bacterial infection.

Hyatt LD, Wasserman GA, Rah YJ, Matsuura KY, Coleman FT, Hilliard KL, Pepper-Cunningham ZA, Ieong M, Stumpo DJ, Blackshear PJ, Quinton LJ, Mizgerd JP, Jones MR.

PLoS One. 2014 Oct 9;9(10):e109072. doi: 10.1371/journal.pone.0109072. eCollection 2014.

13.

ZFP36-FOSB fusion defines a subset of epithelioid hemangioma with atypical features.

Antonescu CR, Chen HW, Zhang L, Sung YS, Panicek D, Agaram NP, Dickson BC, Krausz T, Fletcher CD.

Genes Chromosomes Cancer. 2014 Nov;53(11):951-9. doi: 10.1002/gcc.22206. Epub 2014 Jul 18.

14.

Endothelial dysfunction in tristetraprolin-deficient mice is not caused by enhanced tumor necrosis factor-α expression.

Bollmann F, Wu Z, Oelze M, Siuda D, Xia N, Henke J, Daiber A, Li H, Stumpo DJ, Blackshear PJ, Kleinert H, Pautz A.

J Biol Chem. 2014 May 30;289(22):15653-65. doi: 10.1074/jbc.M114.566984. Epub 2014 Apr 11.

15.

Mutational and structural analysis of the tandem zinc finger domain of tristetraprolin.

Lai WS, Perera L, Hicks SN, Blackshear PJ.

J Biol Chem. 2014 Jan 3;289(1):565-80. doi: 10.1074/jbc.M113.466326. Epub 2013 Nov 19.

16.

Tristetraprolin regulation of interleukin 23 mRNA stability prevents a spontaneous inflammatory disease.

Molle C, Zhang T, Ysebrant de Lendonck L, Gueydan C, Andrianne M, Sherer F, Van Simaeys G, Blackshear PJ, Leo O, Goriely S.

J Exp Med. 2013 Aug 26;210(9):1675-84. doi: 10.1084/jem.20120707. Epub 2013 Aug 12.

17.

Life without TTP: apparent absence of an important anti-inflammatory protein in birds.

Lai WS, Stumpo DJ, Kennington EA, Burkholder AB, Ward JM, Fargo DL, Blackshear PJ.

Am J Physiol Regul Integr Comp Physiol. 2013 Oct 1;305(7):R689-700. doi: 10.1152/ajpregu.00310.2013. Epub 2013 Jul 31.

18.

The 5'-3' exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277-3p in Drosophila wing imaginal discs.

Jones CI, Grima DP, Waldron JA, Jones S, Parker HN, Newbury SF.

RNA Biol. 2013 Aug;10(8):1345-55. doi: 10.4161/rna.25354. Epub 2013 Jun 13.

19.

mRNA-binding protein ZFP36 is expressed in atherosclerotic lesions and reduces inflammation in aortic endothelial cells.

Zhang H, Taylor WR, Joseph G, Caracciolo V, Gonzales DM, Sidell N, Seli E, Blackshear PJ, Kallen CB.

Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1212-20. doi: 10.1161/ATVBAHA.113.301496. Epub 2013 Apr 4.

20.

Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action.

Brooks SA, Blackshear PJ.

Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):666-79. doi: 10.1016/j.bbagrm.2013.02.003. Epub 2013 Feb 18. Review.

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