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Gimap5-dependent inactivation of GSK3β is required for CD4+ T cell homeostasis and prevention of immune pathology.

Patterson AR, Endale M, Lampe K, Aksoylar HI, Flagg A, Woodgett JR, Hildeman D, Jordan MB, Singh H, Kucuk Z, Bleesing J, Hoebe K.

Nat Commun. 2018 Jan 30;9(1):430. doi: 10.1038/s41467-018-02897-7.


Multifaceted Roles of GSK-3 in Cancer and Autophagy-Related Diseases.

Mancinelli R, Carpino G, Petrungaro S, Mammola CL, Tomaipitinca L, Filippini A, Facchiano A, Ziparo E, Giampietri C.

Oxid Med Cell Longev. 2017;2017:4629495. doi: 10.1155/2017/4629495. Epub 2017 Dec 12. Review.


Transcriptomics, metabolomics and histology indicate that high-carbohydrate diet negatively affects the liver health of blunt snout bream (Megalobrama amblycephala).

Prisingkorn W, Prathomya P, Jakovlić I, Liu H, Zhao YH, Wang WM.

BMC Genomics. 2017 Nov 9;18(1):856. doi: 10.1186/s12864-017-4246-9.


Defatting of acetone leaf extract of Acacia karroo (Hayne) enhances its hypoglycaemic potential.

Njanje I, Bagla VP, Beseni BK, Mbazima V, Lebogo KW, Mampuru L, Mokgotho MP.

BMC Complement Altern Med. 2017 Oct 23;17(1):482. doi: 10.1186/s12906-017-1987-6.


Glycogen synthase kinase-3β inhibitor ameliorates imbalance of connexin 43 in an acute kidney injury model.

Wang Y, Tong K.

Toxicol Rep. 2015 Oct 19;2:1391-1395. doi: 10.1016/j.toxrep.2015.10.005. eCollection 2015.


Phosphoproteomics reveals that glycogen synthase kinase-3 phosphorylates multiple splicing factors and is associated with alternative splicing.

Shinde MY, Sidoli S, Kulej K, Mallory MJ, Radens CM, Reicherter AL, Myers RL, Barash Y, Lynch KW, Garcia BA, Klein PS.

J Biol Chem. 2017 Nov 3;292(44):18240-18255. doi: 10.1074/jbc.M117.813527. Epub 2017 Sep 15.


Failure to Inactivate Nuclear GSK3β by Ser389-Phosphorylation Leads to Focal Neuronal Death and Prolonged Fear Response.

Thornton TM, Hare B, Colié S, Pendlebury WW, Nebreda AR, Falls W, Jaworski DM, Rincon M.

Neuropsychopharmacology. 2018 Jan;43(2):393-405. doi: 10.1038/npp.2017.187. Epub 2017 Aug 17.


In vivo regulation of glycogen synthase kinase 3β activity in neurons and brains.

Krishnankutty A, Kimura T, Saito T, Aoyagi K, Asada A, Takahashi SI, Ando K, Ohara-Imaizumi M, Ishiguro K, Hisanaga SI.

Sci Rep. 2017 Aug 17;7(1):8602. doi: 10.1038/s41598-017-09239-5.


Entanglement of GSK-3β, β-catenin and TGF-β1 signaling network to regulate myocardial fibrosis.

Guo Y, Gupte M, Umbarkar P, Singh AP, Sui JY, Force T, Lal H.

J Mol Cell Cardiol. 2017 Sep;110:109-120. doi: 10.1016/j.yjmcc.2017.07.011. Epub 2017 Jul 27. Review.


The regulation of Hh/Gli1 signaling cascade involves Gsk3β- mediated mechanism in estrogen-derived endometrial hyperplasia.

Kaushal JB, Sankhwar P, Kumari S, Popli P, Shukla V, Hussain MK, Hajela K, Dwivedi A.

Sci Rep. 2017 Jul 26;7(1):6557. doi: 10.1038/s41598-017-06370-1.


Long non-coding RNA DGCR5 is involved in the regulation of proliferation, migration and invasion of lung cancer by targeting miR-1180.

Chen EG, Zhang JS, Xu S, Zhu XJ, Hu HH.

Am J Cancer Res. 2017 Jul 1;7(7):1463-1475. eCollection 2017.


Molecular regulation and pharmacological targeting of the β-catenin destruction complex.

van Kappel EC, Maurice MM.

Br J Pharmacol. 2017 Dec;174(24):4575-4588. doi: 10.1111/bph.13922. Epub 2017 Aug 11. Review.


A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

Hou P, Wu C, Wang Y, Qi R, Bhavanasi D, Zuo Z, Dos Santos C, Chen S, Chen Y, Zheng H, Wang H, Perl A, Guo D, Huang J.

Cancer Res. 2017 Aug 15;77(16):4402-4413. doi: 10.1158/0008-5472.CAN-16-1627. Epub 2017 Jun 16.


Hepatic Insulin Resistance and Altered Gluconeogenic Pathway in Premature Baboons.

McGill-Vargas L, Gastaldelli A, Liang H, Anzueto Guerra D, Johnson-Pais T, Seidner S, McCurnin D, Muscogiuri G, DeFronzo R, Musi N, Blanco C.

Endocrinology. 2017 May 1;158(5):1140-1151. doi: 10.1210/en.2016-1806.


Recent advances in understanding the cellular roles of GSK-3.

Cormier KW, Woodgett JR.

F1000Res. 2017 Feb 20;6. pii: F1000 Faculty Rev-167. doi: 10.12688/f1000research.10557.1. eCollection 2017. Review.


Acetaminophen attenuates lipopolysaccharide-induced cognitive impairment through antioxidant activity.

Zhao WX, Zhang JH, Cao JB, Wang W, Wang DX, Zhang XY, Yu J, Zhang YY, Zhang YZ, Mi WD.

J Neuroinflammation. 2017 Jan 21;14(1):17. doi: 10.1186/s12974-016-0781-6.


Phosphorylation of SKAP by GSK3β ensures chromosome segregation by a temporal inhibition of Kif2b activity.

Qin B, Cao D, Wu H, Mo F, Shao H, Chu J, Powell M, Aikhionbare F, Wang D, Fu C, He P, Pan W, Wang W, Liu X, Yao X.

Sci Rep. 2016 Dec 16;6:38791. doi: 10.1038/srep38791.


Novel Non-phosphorylated Serine 9/21 GSK3β/α Antibodies: Expanding the Tools for Studying GSK3 Regulation.

Grabinski T, Kanaan NM.

Front Mol Neurosci. 2016 Nov 17;9:123. eCollection 2016.

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