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Items: 1 to 20 of 102

1.

Survey of single-nucleotide polymorphisms in the gene encoding human deoxyribonuclease I-like 2 producing loss of function potentially implicated in the pathogenesis of parakeratosis.

Ueki M, Takeshita H, Utsunomiya N, Chino T, Oyama N, Hasegawa M, Kimura-Kataoka K, Fujihara J, Iida R, Yasuda T.

PLoS One. 2017 Apr 10;12(4):e0175083. doi: 10.1371/journal.pone.0175083. eCollection 2017.

2.

Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damage.

Suspène R, Mussil B, Laude H, Caval V, Berry N, Bouzidi MS, Thiers V, Wain-Hobson S, Vartanian JP.

Nucleic Acids Res. 2017 Apr 7;45(6):3231-3241. doi: 10.1093/nar/gkx001.

3.

Promyelocytic extracellular chromatin exacerbates coagulation and fibrinolysis in acute promyelocytic leukemia.

Cao M, Li T, He Z, Wang L, Yang X, Kou Y, Zou L, Dong X, Novakovic VA, Bi Y, Kou J, Yu B, Fang S, Wang J, Zhou J, Shi J.

Blood. 2017 Mar 30;129(13):1855-1864. doi: 10.1182/blood-2016-09-739334. Epub 2017 Jan 4.

PMID:
28053193
4.

Lupus pathobiology based on genomics.

Saeed M.

Immunogenetics. 2017 Jan;69(1):1-12. doi: 10.1007/s00251-016-0961-7. Epub 2016 Dec 8. Review.

5.

Nucleic acid-sensing TLRs: trafficking and regulation.

Majer O, Liu B, Barton GM.

Curr Opin Immunol. 2017 Feb;44:26-33. doi: 10.1016/j.coi.2016.10.003. Epub 2016 Nov 28. Review.

PMID:
27907816
6.

Excessive Cytosolic DNA Fragments as a Potential Trigger of Graves' Disease: An Encrypted Message Sent by Animal Models.

Luo Y, Yoshihara A, Oda K, Ishido Y, Suzuki K.

Front Endocrinol (Lausanne). 2016 Nov 14;7:144. eCollection 2016. Review.

7.

AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling.

Prantner D, Perkins DJ, Vogel SN.

J Biol Chem. 2017 Jan 6;292(1):292-304. doi: 10.1074/jbc.M116.763268. Epub 2016 Nov 22.

PMID:
27879319
8.

Insights from Mendelian Interferonopathies: Comparison of CANDLE, SAVI with AGS, Monogenic Lupus.

Kim H, Sanchez GA, Goldbach-Mansky R.

J Mol Med (Berl). 2016 Oct;94(10):1111-1127. Epub 2016 Sep 27. Review.

PMID:
27678529
9.

New Insights into Neutrophil Extracellular Traps: Mechanisms of Formation and Role in Inflammation.

Yang H, Biermann MH, Brauner JM, Liu Y, Zhao Y, Herrmann M.

Front Immunol. 2016 Aug 12;7:302. doi: 10.3389/fimmu.2016.00302. eCollection 2016. Review.

10.

Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis.

Mistry P, Kaplan MJ.

Clin Immunol. 2016 Aug 9. pii: S1521-6616(16)30277-7. doi: 10.1016/j.clim.2016.08.010. [Epub ahead of print]

PMID:
27519955
11.

Type I interferonopathies in pediatric rheumatology.

Volpi S, Picco P, Caorsi R, Candotti F, Gattorno M.

Pediatr Rheumatol Online J. 2016 Jun 4;14(1):35. doi: 10.1186/s12969-016-0094-4. Review.

12.

Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.

Deng Y, Zhao J, Sakurai D, Sestak AL, Osadchiy V, Langefeld CD, Kaufman KM, Kelly JA, James JA, Petri MA, Bae SC, Alarcón-Riquelme ME, Alarcón GS, Anaya JM, Criswell LA, Freedman BI, Kamen DL, Gilkeson GS, Jacob CO, Merrill JT, Gaffney PM, Sivils KM, Niewold TB, Ramsey-Goldman R, Reveille JD, Scofield RH, Stevens AM, Boackle SA, Vilá LM, Sohn II, Lee S, Chang DM, Song YW, Vyse TJ, Harley JB, Brown EE, Edberg JC, Kimberly RP, Cantor RM, Hahn BH, Grossman JM, Tsao BP.

Ann Rheum Dis. 2016 Nov;75(11):2007-2013. doi: 10.1136/annrheumdis-2015-208441. Epub 2016 Jan 18.

PMID:
26783109
13.

Neutrophil extracellular traps (Nets) impact upon autoimmune disorders.

Pruchniak MP, Kotuła I, Manda-Handzlik A.

Cent Eur J Immunol. 2015;40(2):217-24. doi: 10.5114/ceji.2015.52836. Epub 2015 Aug 3. Review.

14.

Innate Immune Signaling by, and Genetic Adjuvants for DNA Vaccination.

Kobiyama K, Jounai N, Aoshi T, Tozuka M, Takeshita F, Coban C, Ishii KJ.

Vaccines (Basel). 2013 Jul 18;1(3):278-92. doi: 10.3390/vaccines1030278. Review.

15.

Immunogenetics of systemic lupus erythematosus: A comprehensive review.

Ghodke-Puranik Y, Niewold TB.

J Autoimmun. 2015 Nov;64:125-36. doi: 10.1016/j.jaut.2015.08.004. Epub 2015 Aug 29. Review.

16.

A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources.

Leffler J, Ciacma K, Gullstrand B, Bengtsson AA, Martin M, Blom AM.

Arthritis Res Ther. 2015 Aug 13;17:205. doi: 10.1186/s13075-015-0726-y.

17.

C1q rs292001 polymorphism and C1q antibodies in juvenile lupus and their relation to lupus nephritis.

Mosaad YM, Hammad A, Fawzy Z, El-Refaaey A, Tawhid Z, Hammad EM, Youssef LF, ElAttar EA, Radwan DF, Fawzy IM.

Clin Exp Immunol. 2015 Oct;182(1):23-34. doi: 10.1111/cei.12666. Epub 2015 Jul 28.

18.

MicroRNAs in autoimmune disease.

Rauniyar VK, Wu W, Yang H.

Auto Immun Highlights. 2011 Jul 12;2(2):59-65. doi: 10.1007/s13317-011-0022-z. eCollection 2011 Nov. Review.

19.

DNaseI protects against Paraquat-induced acute lung injury and pulmonary fibrosis mediated by mitochondrial DNA.

Li G, Yuzhen L, Yi C, Xiaoxiang C, Wei Z, Changqing Z, Shuang Y.

Biomed Res Int. 2015;2015:386952. doi: 10.1155/2015/386952. Epub 2015 Feb 11.

20.

Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.

Günther C, Kind B, Reijns MA, Berndt N, Martinez-Bueno M, Wolf C, Tüngler V, Chara O, Lee YA, Hübner N, Bicknell L, Blum S, Krug C, Schmidt F, Kretschmer S, Koss S, Astell KR, Ramantani G, Bauerfeind A, Morris DL, Cunninghame Graham DS, Bubeck D, Leitch A, Ralston SH, Blackburn EA, Gahr M, Witte T, Vyse TJ, Melchers I, Mangold E, Nöthen MM, Aringer M, Kuhn A, Lüthke K, Unger L, Bley A, Lorenzi A, Isaacs JD, Alexopoulou D, Conrad K, Dahl A, Roers A, Alarcon-Riquelme ME, Jackson AP, Lee-Kirsch MA.

J Clin Invest. 2015 Jan;125(1):413-24. doi: 10.1172/JCI78001. Epub 2014 Dec 15.

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