Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 57

1.

Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways.

Wee P, Wang Z.

Cancers (Basel). 2017 May 17;9(5). pii: E52. doi: 10.3390/cancers9050052. Review.

2.

Bipartite Role of Heat Shock Protein 90 (Hsp90) Keeps CRAF Kinase Poised for Activation.

Mitra S, Ghosh B, Gayen N, Roy J, Mandal AK.

J Biol Chem. 2016 Nov 18;291(47):24579-24593. Epub 2016 Oct 4.

PMID:
27703006
3.

Activation loop phosphorylation regulates B-Raf in vivo and transformation by B-Raf mutants.

Köhler M, Röring M, Schorch B, Heilmann K, Stickel N, Fiala GJ, Schmitt LC, Braun S, Ehrenfeld S, Uhl FM, Kaltenbacher T, Weinberg F, Herzog S, Zeiser R, Schamel WW, Jumaa H, Brummer T.

EMBO J. 2016 Jan 18;35(2):143-61. doi: 10.15252/embj.201592097. Epub 2015 Dec 10.

4.

Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation.

Jambrina PG, Rauch N, Pilkington R, Rybakova K, Nguyen LK, Kholodenko BN, Buchete NV, Kolch W, Rosta E.

Angew Chem Int Ed Engl. 2016 Jan 18;55(3):983-6. doi: 10.1002/anie.201509272. Epub 2015 Dec 8.

5.

A phosphotyrosine switch for cargo sequestration at clathrin-coated buds.

Chakraborty S, Umasankar PK, Preston GM, Khandelwal P, Apodaca G, Watkins SC, Traub LM.

J Biol Chem. 2014 Jun 20;289(25):17497-514. doi: 10.1074/jbc.M114.556589. Epub 2014 May 5.

6.

PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.

Li X, Stevens PD, Liu J, Yang H, Wang W, Wang C, Zeng Z, Schmidt MD, Yang M, Lee EY, Gao T.

Gastroenterology. 2014 May;146(5):1301-12.e1-10. doi: 10.1053/j.gastro.2014.02.003. Epub 2014 Feb 11.

7.

Allosteric activation of functionally asymmetric RAF kinase dimers.

Hu J, Stites EC, Yu H, Germino EA, Meharena HS, Stork PJ, Kornev AP, Taylor SS, Shaw AS.

Cell. 2013 Aug 29;154(5):1036-46. doi: 10.1016/j.cell.2013.07.046.

8.

AKT upregulates B-Raf Ser445 phosphorylation and ERK1/2 activation in prostate cancer cells in response to androgen depletion.

Hong SK, Jeong JH, Chan AM, Park JI.

Exp Cell Res. 2013 Jul 15;319(12):1732-43. doi: 10.1016/j.yexcr.2013.05.008. Epub 2013 May 20.

9.

The importance of serine 776 in Ataxin-1 partner selection: a FRET analysis.

Menon RP, Soong D, de Chiara C, Holt MR, Anilkumar N, Pastore A.

Sci Rep. 2012;2:919. doi: 10.1038/srep00919. Epub 2012 Dec 4.

10.

SEL-10/Fbw7-dependent negative feedback regulation of LIN-45/Braf signaling in C. elegans via a conserved phosphodegron.

de la Cova C, Greenwald I.

Genes Dev. 2012 Nov 15;26(22):2524-35. doi: 10.1101/gad.203703.112.

11.

Increased BRAF heterodimerization is the common pathogenic mechanism for noonan syndrome-associated RAF1 mutants.

Wu X, Yin J, Simpson J, Kim KH, Gu S, Hong JH, Bayliss P, Backx PH, Neel BG, Araki T.

Mol Cell Biol. 2012 Oct;32(19):3872-90. doi: 10.1128/MCB.00751-12. Epub 2012 Jul 23.

12.

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling.

Röring M, Herr R, Fiala GJ, Heilmann K, Braun S, Eisenhardt AE, Halbach S, Capper D, von Deimling A, Schamel WW, Saunders DN, Brummer T.

EMBO J. 2012 May 30;31(11):2629-47. doi: 10.1038/emboj.2012.100. Epub 2012 Apr 17.

13.

Activation kinetics of RAF protein in the ternary complex of RAF, RAS-GTP, and kinase on the plasma membrane of living cells: single-molecule imaging analysis.

Hibino K, Shibata T, Yanagida T, Sako Y.

J Biol Chem. 2011 Oct 21;286(42):36460-8. doi: 10.1074/jbc.M111.262675. Epub 2011 Aug 23.

14.

Targeting oncogenic BRAF in human cancer.

Pratilas CA, Xing F, Solit DB.

Curr Top Microbiol Immunol. 2012;355:83-98. doi: 10.1007/82_2011_162.

15.

Raf family kinases: old dogs have learned new tricks.

Matallanas D, Birtwistle M, Romano D, Zebisch A, Rauch J, von Kriegsheim A, Kolch W.

Genes Cancer. 2011 Mar;2(3):232-60. doi: 10.1177/1947601911407323.

16.
17.

A(₂A) adenosine receptor (A(₂A)AR) as a therapeutic target in diabetic retinopathy.

Ibrahim AS, El-Shishtawy MM, Zhang W, Caldwell RB, Liou GI.

Am J Pathol. 2011 May;178(5):2136-45. doi: 10.1016/j.ajpath.2011.01.018.

18.

Cyclic AMP-mediated cyst expansion.

Wallace DP.

Biochim Biophys Acta. 2011 Oct;1812(10):1291-300. doi: 10.1016/j.bbadis.2010.11.005. Epub 2010 Nov 28. Review.

19.

Regulation of Erk1/2 activation by osteopontin in PC3 human prostate cancer cells.

Robertson BW, Bonsal L, Chellaiah MA.

Mol Cancer. 2010 Sep 26;9:260. doi: 10.1186/1476-4598-9-260.

20.

The Role of B-RAF Mutations in Melanoma and the Induction of EMT via Dysregulation of the NF-κB/Snail/RKIP/PTEN Circuit.

Lin K, Baritaki S, Militello L, Malaponte G, Bevelacqua Y, Bonavida B.

Genes Cancer. 2010 May;1(5):409-420.

Supplemental Content

Support Center