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Non-Hodgkin and Hodgkin Lymphomas Select for Overexpression of BCLW.

Adams CM, Mitra R, Gong JZ, Eischen CM.

Clin Cancer Res. 2017 Nov 15;23(22):7119-7129. doi: 10.1158/1078-0432.CCR-17-1144. Epub 2017 Aug 29.


BCL-W has a fundamental role in B cell survival and lymphomagenesis.

Adams CM, Kim AS, Mitra R, Choi JK, Gong JZ, Eischen CM.

J Clin Invest. 2017 Feb 1;127(2):635-650. doi: 10.1172/JCI89486. Epub 2017 Jan 17.


MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL.

Vikström IB, Slomp A, Carrington EM, Moesbergen LM, Chang C, Kelly GL, Glaser SP, Jansen JH, Leusen JH, Strasser A, Huang DC, Lew AM, Peperzak V, Tarlinton DM.

Cell Death Dis. 2016 Aug 25;7(8):e2345. doi: 10.1038/cddis.2016.237.


MiR-133b regulates bladder cancer cell proliferation and apoptosis by targeting Bcl-w and Akt1.

Chen XN, Wang KF, Xu ZQ, Li SJ, Liu Q, Fu DH, Wang X, Wu B.

Cancer Cell Int. 2014 Jul 19;14:70. doi: 10.1186/s12935-014-0070-3. eCollection 2014.


Anti-apoptotic BCL-2 family proteins in acute neural injury.

Anilkumar U, Prehn JH.

Front Cell Neurosci. 2014 Sep 30;8:281. doi: 10.3389/fncel.2014.00281. eCollection 2014. Review.


Contribution of apoptosis-associated signaling pathways to epileptogenesis: lessons from Bcl-2 family knockouts.

Henshall DC, Engel T.

Front Cell Neurosci. 2013 Jul 16;7:110. doi: 10.3389/fncel.2013.00110. eCollection 2013.


Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration.

Cosker KE, Pazyra-Murphy MF, Fenstermacher SJ, Segal RA.

J Neurosci. 2013 Mar 20;33(12):5195-207. doi: 10.1523/JNEUROSCI.3862-12.2013.


Dual Trade of Bcl-2 and Bcl-xL in islet physiology: balancing life and death with metabolism secretion coupling.

Soria B, Gauthier BR.

Diabetes. 2013 Jan;62(1):18-21. doi: 10.2337/db12-1023. No abstract available.


Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice.

Kelly PN, Grabow S, Delbridge AR, Adams JM, Strasser A.

Cell Death Differ. 2013 Jan;20(1):57-63. doi: 10.1038/cdd.2012.92. Epub 2012 Jul 20.


The antiapoptotic protein Mcl-1 controls the type of cell death in Theiler's virus-infected BHK-21 cells.

Arslan SY, Son KN, Lipton HL.

J Virol. 2012 Feb;86(4):1922-9. doi: 10.1128/JVI.06516-11. Epub 2011 Nov 30.


Pharmacological blockade of Bcl-2, Bcl-x(L) and Bcl-w by the BH3 mimetic ABT-737 has only minor impact on tumour development in p53-deficient mice.

Grabow S, Waring P, Happo L, Cook M, Mason KD, Kelly PN, Strasser A.

Cell Death Differ. 2012 Apr;19(4):623-32. doi: 10.1038/cdd.2011.133. Epub 2011 Oct 14.


The essential role of evasion from cell death in cancer.

Kelly GL, Strasser A.

Adv Cancer Res. 2011;111:39-96. doi: 10.1016/B978-0-12-385524-4.00002-7. Review.


Sensory neuropathy attributable to loss of Bcl-w.

Courchesne SL, Karch C, Pazyra-Murphy MF, Segal RA.

J Neurosci. 2011 Feb 2;31(5):1624-34. doi: 10.1523/JNEUROSCI.3347-10.2011.


Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis.

Crawford AC, Riggins RB, Shajahan AN, Zwart A, Clarke R.

PLoS One. 2010 Jan 6;5(1):e8604. doi: 10.1371/journal.pone.0008604.


The cytosolic domain of Bcl-2 oligomerizes to form pores in model mitochondrial outer membrane at acidic pH.

Peng J, Lapolla SM, Zhang Z, Lin J.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Jun;26(3):631-7.


The cytosolic domain of Bcl-2 forms small pores in model mitochondrial outer membrane after acidic pH-induced membrane association.

Peng J, Lapolla SM, Zhang Z, Lin J.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Feb;26(1):130-7.


Akt regulates drug-induced cell death through Bcl-w downregulation.

Garofalo M, Quintavalle C, Zanca C, De Rienzo A, Romano G, Acunzo M, Puca L, Incoronato M, Croce CM, Condorelli G.

PLoS One. 2008;3(12):e4070. doi: 10.1371/journal.pone.0004070. Epub 2008 Dec 30.


Bcl-XL inhibits membrane permeabilization by competing with Bax.

Billen LP, Kokoski CL, Lovell JF, Leber B, Andrews DW.

PLoS Biol. 2008 Jun 10;6(6):e147. doi: 10.1371/journal.pbio.0060147.

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