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Items: 19


Targeting Cell Survival Proteins for Cancer Cell Death.

Pandey MK, Prasad S, Tyagi AK, Deb L, Huang J, Karelia DN, Amin SG, Aggarwal BB.

Pharmaceuticals (Basel). 2016 Feb 25;9(1). pii: E11. doi: 10.3390/ph9010011. Review.


A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapy.

Chaudhary AK, Yadav N, Bhat TA, O'Malley J, Kumar S, Chandra D.

Drug Discov Today. 2016 Jan;21(1):38-47. doi: 10.1016/j.drudis.2015.07.014. Epub 2015 Jul 30. Review.


The role of E3 ligases in the ubiquitin-dependent regulation of spermatogenesis.

Richburg JH, Myers JL, Bratton SB.

Semin Cell Dev Biol. 2014 Jun;30:27-35. doi: 10.1016/j.semcdb.2014.03.001. Epub 2014 Mar 12. Review.


IAP proteins as targets for drug development in oncology.

Dubrez L, Berthelet J, Glorian V.

Onco Targets Ther. 2013 Sep 16;9:1285-304. doi: 10.2147/OTT.S33375. Review.


CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling.

Starokadomskyy P, Gluck N, Li H, Chen B, Wallis M, Maine GN, Mao X, Zaidi IW, Hein MY, McDonald FJ, Lenzner S, Zecha A, Ropers HH, Kuss AW, McGaughran J, Gecz J, Burstein E.

J Clin Invest. 2013 May;123(5):2244-56. doi: 10.1172/JCI66466. Epub 2013 Apr 8.


Inhibitor of apoptosis protein-like protein-2 as a novel serological biomarker for breast cancer.

Xiang M, Zhou W, Gao D, Fang X, Liu Q.

Int J Mol Sci. 2012 Dec 7;13(12):16737-50. doi: 10.3390/ijms131216737.


Antisense oligonucleotide targeting Livin induces apoptosis of human bladder cancer cell via a mechanism involving caspase 3.

Liu C, Wu X, Luo C, Hu Z, Yin Z, He Y, Du H, Zhang W, Jiang Q, Lin Y.

J Exp Clin Cancer Res. 2010 Jun 3;29:63. doi: 10.1186/1756-9966-29-63.


Role of IAPs in prostate cancer progression: immunohistochemical study in normal and pathological (benign hyperplastic, prostatic intraepithelial neoplasia and cancer) human prostate.

Rodríguez-Berriguete G, Fraile B, de Bethencourt FR, Prieto-Folgado A, Bartolome N, Nuñez C, Prati B, Martínez-Onsurbe P, Olmedilla G, Paniagua R, Royuela M.

BMC Cancer. 2010 Jan 15;10:18. doi: 10.1186/1471-2407-10-18.


Induction of neuronal apoptosis inhibitory protein expression in response to androgen deprivation in prostate cancer.

Chiu HH, Yong TM, Wang J, Wang Y, Vessella RL, Ueda T, Wang YZ, Sadar MD.

Cancer Lett. 2010 Jun 28;292(2):176-85. doi: 10.1016/j.canlet.2009.11.023. Epub 2009 Dec 30.


Identification of an Xiap-like pseudogene on mouse chromosome 7.

Kotevski A, Cook WD, Vaux DL, Callus BA.

PLoS One. 2009 Nov 30;4(11):e8078. doi: 10.1371/journal.pone.0008078.


Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk.

Young JE, Garden GA, Martinez RA, Tanaka F, Sandoval CM, Smith AC, Sopher BL, Lin A, Fischbeck KH, Ellerby LM, Morrison RS, Taylor JP, La Spada AR.

J Neurosci. 2009 Feb 18;29(7):1987-97. doi: 10.1523/JNEUROSCI.4072-08.2009.


COMMD1 expression is controlled by critical residues that determine XIAP binding.

Maine GN, Mao X, Muller PA, Komarck CM, Klomp LW, Burstein E.

Biochem J. 2009 Jan 15;417(2):601-9. doi: 10.1042/BJ20080854.


Repeated recruitment of LTR retrotransposons as promoters by the anti-apoptotic locus NAIP during mammalian evolution.

Romanish MT, Lock WM, van de Lagemaat LN, Dunn CA, Mager DL.

PLoS Genet. 2007 Jan 12;3(1):e10. Epub 2006 Dec 6.


Differential regulation of survivin expression and apoptosis by vitamin D3 compounds in two isogenic MCF-7 breast cancer cell sublines.

Li F, Ling X, Huang H, Brattain L, Apontes P, Wu J, Binderup L, Brattain MG.

Oncogene. 2005 Feb 17;24(8):1385-95.


IAP proteins: sticking it to Smac.

Duckett CS.

Biochem J. 2005 Jan 1;385(Pt 1):e1-2.


The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition.

Shin H, Renatus M, Eckelman BP, Nunes VA, Sampaio CA, Salvesen GS.

Biochem J. 2005 Jan 1;385(Pt 1):1-10.


Upstream regulatory role for XIAP in receptor-mediated apoptosis.

Wilkinson JC, Cepero E, Boise LH, Duckett CS.

Mol Cell Biol. 2004 Aug;24(16):7003-14.


A novel role for XIAP in copper homeostasis through regulation of MURR1.

Burstein E, Ganesh L, Dick RD, van De Sluis B, Wilkinson JC, Klomp LW, Wijmenga C, Brewer GJ, Nabel GJ, Duckett CS.

EMBO J. 2004 Jan 14;23(1):244-54. Epub 2003 Dec 18.


Cloning and characterization of the rat homologues of the Inhibitor of Apoptosis protein 1, 2, and 3 genes.

Holcik M, Lefebvre CA, Hicks K, Korneluk RG.

BMC Genomics. 2002;3:5. Epub 2002 Feb 11.

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