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Items: 1 to 20 of 89

1.

SMAD4 feedback regulates the canonical TGF-β signaling pathway to control granulosa cell apoptosis.

Du X, Pan Z, Li Q, Liu H, Li Q.

Cell Death Dis. 2018 Feb 2;9(2):151. doi: 10.1038/s41419-017-0205-2.

2.

BMP-7 enhances SnoN mRNA expression in renal tubular epithelial cells under high-glucose conditions.

Wang Y, Xiao Y, Li S, Shi L, Liu L, Zhang Y, Shi M, Guo B.

Mol Med Rep. 2017 Sep;16(3):3308-3314. doi: 10.3892/mmr.2017.7025. Epub 2017 Jul 17.

3.

Identification of the SUMO E3 ligase PIAS1 as a potential survival biomarker in breast cancer.

Chanda A, Chan A, Deng L, Kornaga EN, Enwere EK, Morris DG, Bonni S.

PLoS One. 2017 May 11;12(5):e0177639. doi: 10.1371/journal.pone.0177639. eCollection 2017.

4.

USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling.

Zhou F, Xie F, Jin K, Zhang Z, Clerici M, Gao R, van Dinther M, Sixma TK, Huang H, Zhang L, Ten Dijke P.

EMBO J. 2017 Jun 1;36(11):1623-1639. doi: 10.15252/embj.201695372. Epub 2017 May 3.

PMID:
28468752
5.

The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness.

Chandhoke AS, Chanda A, Karve K, Deng L, Bonni S.

Oncotarget. 2017 Mar 28;8(13):21001-21014. doi: 10.18632/oncotarget.15471.

6.

Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.

Wang W, Song B, Anbarchian T, Shirazyan A, Sadik JE, Lyons KM.

PLoS Genet. 2016 Oct 14;12(10):e1006352. doi: 10.1371/journal.pgen.1006352. eCollection 2016 Oct.

7.

A decade of the anaphase-promoting complex in the nervous system.

Huang J, Bonni A.

Genes Dev. 2016 Mar 15;30(6):622-38. doi: 10.1101/gad.274324.115. Review.

8.

The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial-mesenchymal transition in a sumoylation-regulated manner.

Chandhoke AS, Karve K, Dadakhujaev S, Netherton S, Deng L, Bonni S.

Cell Death Differ. 2016 May;23(5):876-88. doi: 10.1038/cdd.2015.152. Epub 2015 Dec 18.

9.

Evidence supporting a role for SMAD2/3 in bovine early embryonic development: potential implications for embryotropic actions of follistatin.

Zhang K, Rajput SK, Lee KB, Wang D, Huang J, Folger JK, Knott JG, Zhang J, Smith GW.

Biol Reprod. 2015 Oct;93(4):86. doi: 10.1095/biolreprod.115.130278. Epub 2015 Aug 19.

10.

The influence of SnoN gene silencing by siRNA on the cell proliferation and apoptosis of human pancreatic cancer cells.

Liu C, Zhang H, Zang X, Wang C, Kong Y, Zhang H.

Diagn Pathol. 2015 Apr 18;10:30. doi: 10.1186/s13000-015-0267-3.

11.

TIF1γ protein regulates epithelial-mesenchymal transition by operating as a small ubiquitin-like modifier (SUMO) E3 ligase for the transcriptional regulator SnoN1.

Ikeuchi Y, Dadakhujaev S, Chandhoke AS, Huynh MA, Oldenborg A, Ikeuchi M, Deng L, Bennett EJ, Harper JW, Bonni A, Bonni S.

J Biol Chem. 2014 Sep 5;289(36):25067-78. doi: 10.1074/jbc.M114.575878. Epub 2014 Jul 24.

12.

The regulation of TGF-β/SMAD signaling by protein deubiquitination.

Zhang J, Zhang X, Xie F, Zhang Z, van Dam H, Zhang L, Zhou F.

Protein Cell. 2014 Jul;5(7):503-17. doi: 10.1007/s13238-014-0058-8. Epub 2014 Apr 23. Review.

13.

PMA induces SnoN proteolysis and CD61 expression through an autocrine mechanism.

Li C, Peart N, Xuan Z, Lewis DE, Xia Y, Jin J.

Cell Signal. 2014 Jul;26(7):1369-78. doi: 10.1016/j.cellsig.2014.03.006. Epub 2014 Mar 15.

14.

Oxidative exposure impairs TGF-β pathway via reduction of type II receptor and SMAD3 in human skin fibroblasts.

He T, Quan T, Shao Y, Voorhees JJ, Fisher GJ.

Age (Dordr). 2014 Jun;36(3):9623. doi: 10.1007/s11357-014-9623-6. Epub 2014 Feb 20.

15.

Downregulation of Smurf2, a tumor-suppressive ubiquitin ligase, in triple-negative breast cancers: involvement of the RB-microRNA axis.

Liu X, Gu X, Sun L, Flowers AB, Rademaker AW, Zhou Y, Kiyokawa H.

BMC Cancer. 2014 Feb 3;14:57. doi: 10.1186/1471-2407-14-57.

16.

Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif.

Hamilton MP, Rajapakshe K, Hartig SM, Reva B, McLellan MD, Kandoth C, Ding L, Zack TI, Gunaratne PH, Wheeler DA, Coarfa C, McGuire SE.

Nat Commun. 2013;4:2730. doi: 10.1038/ncomms3730.

17.

SnoN facilitates axonal regeneration after spinal cord injury.

Do JL, Bonni A, Tuszynski MH.

PLoS One. 2013 Aug 2;8(8):e71906. doi: 10.1371/journal.pone.0071906. Print 2013.

18.

Identification of a Novel Link between the Protein Kinase NDR1 and TGFβ Signaling in Epithelial Cells.

Pot I, Patel S, Deng L, Chandhoke AS, Zhang C, Bonni A, Bonni S.

PLoS One. 2013 Jun 26;8(6):e67178. doi: 10.1371/journal.pone.0067178. Print 2013.

19.

SMAD1 deficiency in either endothelial or smooth muscle cells can predispose mice to pulmonary hypertension.

Han C, Hong KH, Kim YH, Kim MJ, Song C, Kim MJ, Kim SJ, Raizada MK, Oh SP.

Hypertension. 2013 May;61(5):1044-52. doi: 10.1161/HYPERTENSIONAHA.111.199158. Epub 2013 Mar 11.

20.

The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1.

Hwang YS, Lee HS, Kamata T, Mood K, Cho HJ, Winterbottom E, Ji YJ, Singh A, Daar IO.

Genes Dev. 2013 Mar 1;27(5):491-503. doi: 10.1101/gad.208355.112.

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