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NOD2 gene variants confer risk for secondary sclerosing cholangitis in critically ill patients.

Jüngst C, Stadlbauer V, Reichert MC, Zimmer V, Weber SN, Ofner-Ziegenfuß L, Voigtländer T, Spindelböck W, Fickert P, Kirchner GI, Lammert F, Lankisch TO, Krawczyk M.

Sci Rep. 2017 Aug 1;7(1):7026. doi: 10.1038/s41598-017-06268-y.


Familial aggregation of inflammatory bowel disease in patients with ulcerative colitis.

Gupta A, Bopanna S, Kedia S, Yadav DP, Goyal S, Jain S, Makharia G, Ahuja V.

Intest Res. 2017 Jul;15(3):388-394. doi: 10.5217/ir.2017.15.3.388. Epub 2017 Jun 12.


Genetic Variability as a Regulator of TLR4 and NOD Signaling in Response to Bacterial Driven DNA Damage Response (DDR) and Inflammation: Focus on the Gastrointestinal (GI) Tract.

Spanou E, Kalisperati P, Pateras IS, Papalampros A, Barbouti A, Tzioufas AG, Kotsinas A, Sougioultzis S.

Front Genet. 2017 May 29;8:65. doi: 10.3389/fgene.2017.00065. eCollection 2017. Review.


Intestinal microbiota, fecal microbiota transplantation, and inflammatory bowel disease.

Weingarden AR, Vaughn BP.

Gut Microbes. 2017 May 4;8(3):238-252. doi: 10.1080/19490976.2017.1290757. Epub 2017 Feb 10.


NLRC3 regulates cellular proliferation and apoptosis to attenuate the development of colorectal cancer.

Karki R, Malireddi RKS, Zhu Q, Kanneganti TD.

Cell Cycle. 2017 Jul 3;16(13):1243-1251. doi: 10.1080/15384101.2017.1317414. Epub 2017 Jun 9.


Mend Your Fences: The Epithelial Barrier and its Relationship With Mucosal Immunity in Inflammatory Bowel Disease.

Martini E, Krug SM, Siegmund B, Neurath MF, Becker C.

Cell Mol Gastroenterol Hepatol. 2017 Mar 23;4(1):33-46. doi: 10.1016/j.jcmgh.2017.03.007. eCollection 2017 Jul. Review.


Uncovering Pathogenic Mechanisms of Inflammatory Bowel Disease Using Mouse Models of Crohn's Disease-Like Ileitis: What is the Right Model?

Cominelli F, Arseneau KO, Rodriguez-Palacios A, Pizarro TT.

Cell Mol Gastroenterol Hepatol. 2017 Mar 6;4(1):19-32. doi: 10.1016/j.jcmgh.2017.02.010. eCollection 2017 Jul. Review.


The Microbiome in Visceral Medicine: Inflammatory Bowel Disease, Obesity and Beyond.

Chiriac MT, Mahapatro M, Neurath MF, Becker C.

Visc Med. 2017 May;33(2):153-162. doi: 10.1159/000470892. Epub 2017 Apr 7. Review.


Roles of intestinal epithelial cells in the maintenance of gut homeostasis.

Okumura R, Takeda K.

Exp Mol Med. 2017 May 26;49(5):e338. doi: 10.1038/emm.2017.20. Review.


Application of Zebrafish Models in Inflammatory Bowel Disease.

Hanyang L, Xuanzhe L, Xuyang C, Yujia Q, Jiarong F, Jun S, Zhihua R.

Front Immunol. 2017 May 3;8:501. doi: 10.3389/fimmu.2017.00501. eCollection 2017. Review.


From sensing to shaping microbiota: insights into the role of NOD2 in intestinal homeostasis and progression of Crohn's disease.

Balasubramanian I, Gao N.

Am J Physiol Gastrointest Liver Physiol. 2017 Jul 1;313(1):G7-G13. doi: 10.1152/ajpgi.00330.2016. Epub 2017 Apr 27. Review.


The impact of rare and low-frequency genetic variants in common disease.

Bomba L, Walter K, Soranzo N.

Genome Biol. 2017 Apr 27;18(1):77. doi: 10.1186/s13059-017-1212-4. Review.


An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes.

Yan J, Hedl M, Abraham C.

J Clin Invest. 2017 Jun 1;127(6):2192-2205. doi: 10.1172/JCI86282. Epub 2017 Apr 24.


Exome Analysis of Rare and Common Variants within the NOD Signaling Pathway.

Andreoletti G, Shakhnovich V, Christenson K, Coelho T, Haggarty R, Afzal NA, Batra A, Petersen BS, Mort M, Beattie RM, Ennis S.

Sci Rep. 2017 Apr 19;7:46454. doi: 10.1038/srep46454.


Editorial: Understanding Crohn's Disease: Immunity, Genes and Microbes.

Sarmento A.

Front Immunol. 2017 Mar 31;8:357. doi: 10.3389/fimmu.2017.00357. eCollection 2017. No abstract available.


Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.

Chirieleison SM, Marsh RA, Kumar P, Rathkey JK, Dubyak GR, Abbott DW.

J Biol Chem. 2017 Jun 9;292(23):9666-9679. doi: 10.1074/jbc.M117.781500. Epub 2017 Apr 12.


Role of autophagy in the pathogenesis of inflammatory bowel disease.

Iida T, Onodera K, Nakase H.

World J Gastroenterol. 2017 Mar 21;23(11):1944-1953. doi: 10.3748/wjg.v23.i11.1944. Review.


Nod2 and Nod2-regulated microbiota protect BALB/c mice from diet-induced obesity and metabolic dysfunction.

Rodriguez-Nunez I, Caluag T, Kirby K, Rudick CN, Dziarski R, Gupta D.

Sci Rep. 2017 Apr 3;7(1):548. doi: 10.1038/s41598-017-00484-2.


The Role of Mucosal Immunity in the Pathogenesis of Necrotizing Enterocolitis.

Hodzic Z, Bolock AM, Good M.

Front Pediatr. 2017 Mar 3;5:40. doi: 10.3389/fped.2017.00040. eCollection 2017. Review.


Negative regulators of the RIG-I-like receptor signaling pathway.

Quicke KM, Diamond MS, Suthar MS.

Eur J Immunol. 2017 Apr;47(4):615-628. doi: 10.1002/eji.201646484. Review.


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