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Items: 1 to 20 of 213

1.

Areca nut extracts mobilize calcium and release pro-inflammatory cytokines from various immune cells.

Faouzi M, Neupane RP, Yang J, Williams P, Penner R.

Sci Rep. 2018 Jan 18;8(1):1075. doi: 10.1038/s41598-017-18996-2.

2.

Markers and Biomarkers of Endothelium: When Something Is Rotten in the State.

Goncharov NV, Nadeev AD, Jenkins RO, Avdonin PV.

Oxid Med Cell Longev. 2017;2017:9759735. doi: 10.1155/2017/9759735. Epub 2017 Nov 23. Review.

3.

Alteration in Intracellular Zn2+ Homeostasis as a Result of TRPM2 Channel Activation Contributes to ROS-Induced Hippocampal Neuronal Death.

Li X, Yang W, Jiang LH.

Front Mol Neurosci. 2017 Dec 12;10:414. doi: 10.3389/fnmol.2017.00414. eCollection 2017.

4.

Regulation of Pain and Itch by TRP Channels.

Moore C, Gupta R, Jordt SE, Chen Y, Liedtke WB.

Neurosci Bull. 2018 Feb;34(1):120-142. doi: 10.1007/s12264-017-0200-8. Epub 2017 Dec 27. Review.

PMID:
29282613
5.

Transient Receptor Potential Melastatin 2 Negatively Regulates LPS-ATP-Induced Caspase-1-Dependent Pyroptosis of Bone Marrow-Derived Macrophage by Modulating ROS Production.

Wang H, Zhou X, Li H, Qian X, Wang Y, Ma L.

Biomed Res Int. 2017;2017:2975648. doi: 10.1155/2017/2975648. Epub 2017 Nov 8.

6.

Glucagon-like peptide-1 potentiates glucose-stimulated insulin secretion via the transient receptor potential melastatin 2 channel.

Pang B, Kim S, Li D, Ma Z, Sun B, Zhang X, Wu Z, Chen L.

Exp Ther Med. 2017 Nov;14(5):5219-5227. doi: 10.3892/etm.2017.5136. Epub 2017 Sep 19.

7.

Different Principles of ADP-Ribose-Mediated Activation and Opposite Roles of the NUDT9 Homology Domain in the TRPM2 Orthologs of Man and Sea Anemone.

Kühn F, Kühn C, Lückhoff A.

Front Physiol. 2017 Oct 31;8:879. doi: 10.3389/fphys.2017.00879. eCollection 2017. Review.

8.

Phospholipid Phosphatase 4 promotes proliferation and tumorigenesis, and activates Ca2+-permeable Cationic Channel in lung carcinoma cells.

Zhang X, Zhang L, Lin B, Chai X, Li R, Liao Y, Deng X, Liu Q, Yang W, Cai Y, Zhou W, Lin Z, Huang W, Zhong M, Lei F, Wu J, Yu S, Li X, Li S, Li Y, Zeng J, Long W, Ren D, Huang Y.

Mol Cancer. 2017 Aug 29;16(1):147. doi: 10.1186/s12943-017-0717-5.

9.

Transient Receptor Potential-Melastatin Channel Family Member 2: Friend or Foe.

Cheung JY, Miller BA.

Trans Am Clin Climatol Assoc. 2017;128:308-329.

10.

Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury.

Mittal M, Nepal S, Tsukasaki Y, Hecquet CM, Soni D, Rehman J, Tiruppathi C, Malik AB.

Circ Res. 2017 Oct 13;121(9):1081-1091. doi: 10.1161/CIRCRESAHA.117.311747. Epub 2017 Aug 8.

PMID:
28790198
11.

2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist.

Fliegert R, Bauche A, Wolf Pérez AM, Watt JM, Rozewitz MD, Winzer R, Janus M, Gu F, Rosche A, Harneit A, Flato M, Moreau C, Kirchberger T, Wolters V, Potter BVL, Guse AH.

Nat Chem Biol. 2017 Sep;13(9):1036-1044. doi: 10.1038/nchembio.2415. Epub 2017 Jun 26.

PMID:
28671679
12.

The TRPM2 channel: A thermo-sensitive metabolic sensor.

Kashio M, Tominaga M.

Channels (Austin). 2017 Sep 3;11(5):426-433. doi: 10.1080/19336950.2017.1344801. Epub 2017 Jun 20.

PMID:
28633002
14.

ADP-ribosyl cyclases regulate early development of the sea urchin.

Ramakrishnan L, Uhlinger K, Dale L, Hamdoun A, Patel S.

Messenger (Los Angel). 2016 Jun 1;5(1-2):100-106. doi: 10.1166/msr.2016.1052.

15.

Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.

Fliegert R, Watt JM, Schöbel A, Rozewitz MD, Moreau C, Kirchberger T, Thomas MP, Sick W, Araujo AC, Harneit A, Potter BVL, Guse AH.

Biochem J. 2017 Jun 16;474(13):2159-2175. doi: 10.1042/BCJ20170091.

16.

Regulation of thermoTRPs by lipids.

Morales-Lázaro SL, Lemus L, Rosenbaum T.

Temperature (Austin). 2016 Nov 1;4(1):24-40. doi: 10.1080/23328940.2016.1254136. eCollection 2017. Review.

17.

Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.

Tykocki NR, Boerman EM, Jackson WF.

Compr Physiol. 2017 Mar 16;7(2):485-581. doi: 10.1002/cphy.c160011. Review.

PMID:
28333380
18.

Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells.

Mortadza SS, Sim JA, Stacey M, Jiang LH.

Sci Rep. 2017 Mar 21;7:45032. doi: 10.1038/srep45032.

19.

Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2.

Yu P, Xue X, Zhang J, Hu X, Wu Y, Jiang LH, Jin H, Luo J, Zhang L, Liu Z, Yang W.

J Gen Physiol. 2017 Feb;149(2):219-235. doi: 10.1085/jgp.201611675. Epub 2017 Jan 20.

20.

Role of the phagosomal redox-sensitive TRP channel TRPM2 in regulating bactericidal activity of macrophages.

Di A, Kiya T, Gong H, Gao X, Malik AB.

J Cell Sci. 2017 Feb 15;130(4):735-744. doi: 10.1242/jcs.196014. Epub 2017 Jan 12.

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