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Items: 1 to 20 of 24

1.

Anti-Inflammatory Activity and Structure-Activity Relationships of Brominated Indoles from a Marine Mollusc.

Ahmad TB, Rudd D, Smith J, Kotiw M, Mouatt P, Seymour LM, Liu L, Benkendorff K.

Mar Drugs. 2017 May 6;15(5). pii: E133. doi: 10.3390/md15050133.

2.

QSAR Analysis for Some 1, 2-Benzisothiazol-3-one Derivatives as Caspase-3 Inhibitors by Stepwise MLR Method.

Hajimahdi Z, Safizadeh F, Zarghi A.

Iran J Pharm Res. 2016 Spring;15(2):439-48.

3.

Imaging radiation response in tumor and normal tissue.

Rafat M, Ali R, Graves EE.

Am J Nucl Med Mol Imaging. 2015 Jun 15;5(4):317-32. eCollection 2015. Review.

4.

Characterization of [(99m)Tc]Duramycin as a SPECT Imaging Agent for Early Assessment of Tumor Apoptosis.

Elvas F, Vangestel C, Rapic S, Verhaeghe J, Gray B, Pak K, Stroobants S, Staelens S, Wyffels L.

Mol Imaging Biol. 2015 Dec;17(6):838-47. doi: 10.1007/s11307-015-0852-6.

5.

Molecular imaging of apoptosis: from micro to macro.

Zeng W, Wang X, Xu P, Liu G, Eden HS, Chen X.

Theranostics. 2015 Feb 20;5(6):559-82. doi: 10.7150/thno.11548. eCollection 2015. Review.

6.

Radiolabeled apoptosis imaging agents for early detection of response to therapy.

Ogawa K, Aoki M.

ScientificWorldJournal. 2014;2014:732603. doi: 10.1155/2014/732603. Epub 2014 Oct 14. Review.

7.

Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies.

Lin YF, Lai TC, Chang CK, Chen CL, Huang MS, Yang CJ, Liu HG, Dong JJ, Chou YA, Teng KH, Chen SH, Tian WT, Jan YH, Hsiao M, Liang PH.

J Clin Invest. 2013 Sep;123(9):3861-75. doi: 10.1172/JCI67951. Epub 2013 Aug 27.

8.

Synthesis, characterization and anticancer activity of certain 3-{4-(5-mercapto-1,3,4-oxadiazole-2-yl)phenylimino}indolin-2-one derivatives.

Gudipati R, Anreddy RN, Manda S.

Saudi Pharm J. 2011 Jul;19(3):153-8. doi: 10.1016/j.jsps.2011.03.002. Epub 2011 Mar 11.

9.

Caspase-3 is involved in the signalling in erythroid differentiation by targeting late progenitors.

Boehm D, Mazurier C, Giarratana MC, Darghouth D, Faussat AM, Harmand L, Douay L.

PLoS One. 2013 May 2;8(5):e62303. doi: 10.1371/journal.pone.0062303. Print 2013.

10.

Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases.

Zhavoronkov A, Smit-McBride Z, Guinan KJ, Litovchenko M, Moskalev A.

J Mol Med (Berl). 2012 Dec;90(12):1361-89. doi: 10.1007/s00109-012-0962-4. Epub 2012 Oct 23. Review.

11.

Catalytic stereoselective synthesis of diverse oxindoles and spirooxindoles from isatins.

MacDonald JP, Badillo JJ, Arevalo GE, Silva-García A, Franz AK.

ACS Comb Sci. 2012 Apr 9;14(4):285-93. doi: 10.1021/co300003c. Epub 2012 Apr 2.

12.

Reducing agents affect inhibitory activities of compounds: results from multiple drug targets.

Lee H, Torres J, Truong L, Chaudhuri R, Mittal A, Johnson ME.

Anal Biochem. 2012 Apr 1;423(1):46-53. doi: 10.1016/j.ab.2012.01.006. Epub 2012 Jan 18.

13.

Copper-catalyzed enantioselective intramolecular alkene amination/intermolecular Heck-type coupling cascade.

Liwosz TW, Chemler SR.

J Am Chem Soc. 2012 Feb 1;134(4):2020-3. doi: 10.1021/ja211272v. Epub 2012 Jan 24.

14.

Synthesis and evaluation of isatin analogs as caspase-3 inhibitors: introduction of a hydrophilic group increases potency in a whole cell assay.

Chu W, Rothfuss J, Zhou D, Mach RH.

Bioorg Med Chem Lett. 2011 Apr 15;21(8):2192-7. doi: 10.1016/j.bmcl.2011.03.015.

15.

Acylideneoxoindoles: a new class of reversible inhibitors of human transglutaminase 2.

Klöck C, Jin X, Choi K, Khosla C, Madrid PB, Spencer A, Raimundo BC, Boardman P, Lanza G, Griffin JH.

Bioorg Med Chem Lett. 2011 May 1;21(9):2692-6. doi: 10.1016/j.bmcl.2010.12.037. Epub 2010 Dec 16.

16.

EMBM - a new enzyme mechanism-based method for rational design of chemical sites of covalent inhibitors.

Traube T, Vijayakumar S, Hirsch M, Uritsky N, Shokhen M, Albeck A.

J Chem Inf Model. 2010 Dec 27;50(12):2256-65. doi: 10.1021/ci100330y. Epub 2010 Nov 19.

17.

Novel tetracyclic structures from the synthesis of thiolactone-isatin hybrids.

Hans RH, Su H, Chibale K.

Beilstein J Org Chem. 2010 Jul 19;6. pii: 78. doi: 10.3762/bjoc.6.78.

18.

Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis.

Peterson QP, Goode DR, West DC, Botham RC, Hergenrother PJ.

Nat Protoc. 2010 Feb;5(2):294-302. doi: 10.1038/nprot.2009.223. Epub 2010 Jan 28.

19.

Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide.

Nguyen QD, Smith G, Glaser M, Perumal M, Arstad E, Aboagye EO.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16375-80. doi: 10.1073/pnas.0901310106. Epub 2009 Sep 3.

20.

Biological targets for isatin and its analogues: Implications for therapy.

Medvedev A, Buneeva O, Glover V.

Biologics. 2007 Jun;1(2):151-62.

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