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Items: 1 to 20 of 45

1.

Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS.

Huang WY, Yan Q, Lin WC, Chung JK, Hansen SD, Christensen SM, Tu HL, Kuriyan J, Groves JT.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8218-23. doi: 10.1073/pnas.1602602113. Epub 2016 Jul 1.

2.

A microarray-based approach to evaluate the functional significance of protein-binding motifs.

Sinzinger MD, Chung YD, Adjobo-Hermans MJ, Brock R.

Anal Bioanal Chem. 2016 May;408(12):3177-84. doi: 10.1007/s00216-016-9382-6. Epub 2016 Feb 18.

3.

Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With Immunotherapy.

Wargo JA, Reuben A, Cooper ZA, Oh KS, Sullivan RJ.

Semin Oncol. 2015 Aug;42(4):601-16. doi: 10.1053/j.seminoncol.2015.05.007. Epub 2015 Jun 3. Review.

4.

Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation.

Devkota S, Joseph RE, Min L, Bruce Fulton D, Andreotti AH.

J Mol Biol. 2015 Aug 28;427(17):2734-47. doi: 10.1016/j.jmb.2015.04.012. Epub 2015 Apr 25.

5.

Proline-rich tyrosine kinase 2 controls PI3-kinase activation downstream of the T cell antigen receptor in human T cells.

Chapman NM, Yoder AN, Barbón KM, Bilal MY, Connolly SF, Houtman JC.

J Leukoc Biol. 2015 Feb;97(2):285-96. doi: 10.1189/jlb.2A1013-568RRR. Epub 2014 Nov 11.

6.

Rictor negatively regulates high-affinity receptors for IgE-induced mast cell degranulation.

Smrz D, Cruse G, Beaven MA, Kirshenbaum A, Metcalfe DD, Gilfillan AM.

J Immunol. 2014 Dec 15;193(12):5924-32. doi: 10.4049/jimmunol.1303495. Epub 2014 Nov 5.

7.

Multiple regulatory roles of the mouse transmembrane adaptor protein NTAL in gene transcription and mast cell physiology.

Polakovicova I, Draberova L, Simicek M, Draber P.

PLoS One. 2014 Aug 25;9(8):e105539. doi: 10.1371/journal.pone.0105539. eCollection 2014.

8.

Phosphorylation site dynamics of early T-cell receptor signaling.

Chylek LA, Akimov V, Dengjel J, Rigbolt KT, Hu B, Hlavacek WS, Blagoev B.

PLoS One. 2014 Aug 22;9(8):e104240. doi: 10.1371/journal.pone.0104240. eCollection 2014.

9.

Activated PLC-γ1 is catalytically induced at LAT but activated PLC-γ1 is localized at both LAT- and TCR-containing complexes.

Cruz-Orcutt N, Vacaflores A, Connolly SF, Bunnell SC, Houtman JC.

Cell Signal. 2014 Apr;26(4):797-805. doi: 10.1016/j.cellsig.2013.12.022. Epub 2014 Jan 8.

10.

Growth factor receptor-bound protein 2 contributes to (hem)immunoreceptor tyrosine-based activation motif-mediated signaling in platelets.

Dütting S, Vögtle T, Morowski M, Schiessl S, Schäfer CM, Watson SK, Hughes CE, Ackermann JA, Radtke D, Hermanns HM, Watson SP, Nitschke L, Nieswandt B.

Circ Res. 2014 Jan 31;114(3):444-453. doi: 10.1161/CIRCRESAHA.114.302670. Epub 2013 Nov 21.

11.

A Novel Phosphopeptide Microarray Based Interactome Map in Breast Cancer Cells Reveals Phosphoprotein-GRB2 Cell Signaling Networks.

Krishnamoorthy S, Liu Z, Hong A, Zhu R, Chen H, Li T, Zhou X, Gao X.

PLoS One. 2013 Jun 27;8(6):e67634. doi: 10.1371/journal.pone.0067634. Print 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/a05f0793-f1af-409d-984e-79444877aec3.

12.

Enhanced function of redirected human T cells expressing linker for activation of T cells that is resistant to ubiquitylation.

Kunii N, Zhao Y, Jiang S, Liu X, Scholler J, Balagopalan L, Samelson LE, Milone MC, June CH.

Hum Gene Ther. 2013 Jan;24(1):27-37. doi: 10.1089/hum.2012.130. Epub 2012 Nov 6.

13.

End-binding protein 1 controls signal propagation from the T cell receptor.

Martín-Cófreces NB, Baixauli F, López MJ, Gil D, Monjas A, Alarcón B, Sánchez-Madrid F.

EMBO J. 2012 Nov 5;31(21):4140-52. doi: 10.1038/emboj.2012.242. Epub 2012 Aug 24.

14.

Transmembrane adaptor proteins in the high-affinity IgE receptor signaling.

Draber P, Halova I, Levi-Schaffer F, Draberova L.

Front Immunol. 2012 Jan 11;2:95. doi: 10.3389/fimmu.2011.00095. eCollection 2011.

15.

The transcription factor Zeb2 regulates signaling in mast cells.

Barbu EA, Zhang J, Berenstein EH, Groves JR, Parks LM, Siraganian RP.

J Immunol. 2012 Jun 15;188(12):6278-86. doi: 10.4049/jimmunol.1102660. Epub 2012 May 4.

16.

The role of nutrition in enhancing immunity in aging.

Pae M, Meydani SN, Wu D.

Aging Dis. 2012 Feb;3(1):91-129. Epub 2011 Sep 30.

17.

Suppression of antigen-specific T cell responses by the Kaposi's sarcoma-associated herpesvirus viral OX2 protein and its cellular orthologue, CD200.

Misstear K, Chanas SA, Rezaee SA, Colman R, Quinn LL, Long HM, Goodyear O, Lord JM, Hislop AD, Blackbourn DJ.

J Virol. 2012 Jun;86(11):6246-57. doi: 10.1128/JVI.07168-11. Epub 2012 Apr 4.

18.

Vav1 oncogenic mutation inhibits T cell receptor-induced calcium mobilization through inhibition of phospholipase Cγ1 activation.

Knyazhitsky M, Moas E, Shaginov E, Luria A, Braiman A.

J Biol Chem. 2012 Jun 1;287(23):19725-35. doi: 10.1074/jbc.M111.309799. Epub 2012 Apr 3.

19.

Analyzing the homeostasis of signaling proteins by a combination of Western blot and fluorescence correlation spectroscopy.

Chung YD, Sinzinger MD, Bovee-Geurts P, Krause M, Dinkla S, Joosten I, Koopman WJ, Adjobo-Hermans MJ, Brock R.

Biophys J. 2011 Dec 7;101(11):2807-15. doi: 10.1016/j.bpj.2011.09.058.

20.

Itk: the rheostat of the T cell response.

Grasis JA, Tsoukas CD.

J Signal Transduct. 2011;2011:297868. doi: 10.1155/2011/297868. Epub 2011 Apr 7.

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