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Coumarin-chalcone hybrid instigates DNA damage by minor groove binding and stabilizes p53 through post translational modifications.

Ashraf R, Hamidullah, Hasanain M, Pandey P, Maheshwari M, Singh LR, Siddiqui MQ, Konwar R, Sashidhara KV, Sarkar J.

Sci Rep. 2017 Mar 28;7:45287. doi: 10.1038/srep45287.


Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression.

Ebata T, Mitsui Y, Sugimoto W, Maeda M, Araki K, Machiyama H, Harada I, Sawada Y, Fujita H, Hirata H, Kawauchi K.

Biomed Res Int. 2017;2017:5158961. doi: 10.1155/2017/5158961. Epub 2017 Jan 16.


Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cells.

Okuda A, Kurokawa S, Takehashi M, Maeda A, Fukuda K, Kubo Y, Nogusa H, Takatani-Nakase T, Okuda S, Ueda K, Tanaka S.

BMC Neurosci. 2017 Jan 17;18(1):14. doi: 10.1186/s12868-016-0333-0.


Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling.

Ebata T, Hirata H, Kawauchi K.

Biomed Res Int. 2016;2016:9231057. doi: 10.1155/2016/9231057. Epub 2016 Dec 18. Review.


Vitamin D receptor deficit induces activation of renin angiotensin system via SIRT1 modulation in podocytes.

Chandel N, Ayasolla K, Wen H, Lan X, Haque S, Saleem MA, Malhotra A, Singhal PC.

Exp Mol Pathol. 2017 Feb;102(1):97-105. doi: 10.1016/j.yexmp.2017.01.001. Epub 2017 Jan 6.


Functional Activation of Mutant p53 by Platinum Analogues in Cisplatin-Resistant Cells Is Dependent on Phosphorylation.

Xie X, He G, Siddik ZH.

Mol Cancer Res. 2017 Mar;15(3):328-339. doi: 10.1158/1541-7786.MCR-16-0257-T. Epub 2016 Dec 28.


Suberoylanilide hydroxamic acid represses glioma stem-like cells.

Hsu CC, Chang WC, Hsu TI, Liu JJ, Yeh SH, Wang JY, Liou JP, Ko CY, Chang KY, Chuang JY.

J Biomed Sci. 2016 Nov 18;23(1):81.


PXR variants: the impact on drug metabolism and therapeutic responses.

Brewer CT, Chen T.

Acta Pharm Sin B. 2016 Sep;6(5):441-449. Epub 2016 Jul 27. Review.


Role of p53 isoforms and aggregations in cancer.

Kim S, An SS.

Medicine (Baltimore). 2016 Jun;95(26):e3993. doi: 10.1097/MD.0000000000003993. Review.


miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis.

Disayabutr S, Kim EK, Cha SI, Green G, Naikawadi RP, Jones KD, Golden JA, Schroeder A, Matthay MA, Kukreja J, Erle DJ, Collard HR, Wolters PJ.

PLoS One. 2016 Jun 30;11(6):e0158367. doi: 10.1371/journal.pone.0158367. eCollection 2016.


Lysines in the tetramerization domain of p53 selectively modulate G1 arrest.

Beckerman R, Yoh K, Mattia-Sansobrino M, Zupnick A, Laptenko O, Karni-Schmidt O, Ahn J, Byeon IJ, Keezer S, Prives C.

Cell Cycle. 2016 Jun 2;15(11):1425-38. doi: 10.1080/15384101.2016.1170270. Epub 2016 May 21.


Cell Differentiation and Checkpoint.

Sancho SC, Ouchi T.

Int J Cancer Res Mol Mech. 2015 Aug;1(2). doi: 10.16966/2381-3318.107. Epub 2015 Jul 2.


Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer.

Lozada EM, Andrysik Z, Yin M, Redilla N, Rice K, Stambrook PJ.

Oncotarget. 2016 Apr 12;7(15):20425-39. doi: 10.18632/oncotarget.7966.


Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination.

Frum RA, Love IM, Damle PK, Mukhopadhyay ND, Palit Deb S, Deb S, Grossman SR.

Mol Cancer Res. 2016 May;14(5):423-36. doi: 10.1158/1541-7786.MCR-15-0363. Epub 2016 Mar 10.


JNK Inhibition Inhibits Lateral Line Neuromast Hair Cell Development.

Cai C, Lin J, Sun S, He Y.

Front Cell Neurosci. 2016 Feb 5;10:19. doi: 10.3389/fncel.2016.00019. eCollection 2016.


DNA repair and aging: the impact of the p53 family.

Nicolai S, Rossi A, Di Daniele N, Melino G, Annicchiarico-Petruzzelli M, Raschellà G.

Aging (Albany NY). 2015 Dec;7(12):1050-65. Review.


Histone deacetylase inhibitors in castration-resistant prostate cancer: molecular mechanism of action and recent clinical trials.

Kaushik D, Vashistha V, Isharwal S, Sediqe SA, Lin MF.

Ther Adv Urol. 2015 Dec;7(6):388-95. doi: 10.1177/1756287215597637. Review.


Nucleocytoplasmic Translocation of UBXN2A Is Required for Apoptosis during DNA Damage Stresses in Colon Cancer Cells.

Abdullah A, Sane S, Freeling JL, Wang H, Zhang D, Rezvani K.

J Cancer. 2015 Sep 3;6(11):1066-78. doi: 10.7150/jca.12134. eCollection 2015.


Phosphorylation of Single Stranded RNA Virus Proteins and Potential for Novel Therapeutic Strategies.

Keck F, Ataey P, Amaya M, Bailey C, Narayanan A.

Viruses. 2015 Oct 12;7(10):5257-73. doi: 10.3390/v7102872. Review.

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