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Items: 1 to 20 of 447


Molecular mechanisms of acetylcholine receptor-lipid interactions: from model membranes to human biology.

Baenziger JE, daCosta CJB.

Biophys Rev. 2013 Mar;5(1):1-9. doi: 10.1007/s12551-012-0078-7. Epub 2012 May 10. Review.


Broad Analysis of Vicinal Disulfides: Occurrences, Conformations with Cis or with Trans Peptides, and Functional Roles Including Sugar Binding.

Richardson JS, Videau LL, Williams CJ, Richardson DC.

J Mol Biol. 2017 May 5;429(9):1321-1335. doi: 10.1016/j.jmb.2017.03.017. Epub 2017 Mar 20.


GABA-ρ receptors: distinctive functions and molecular pharmacology.

Naffaa MM, Hung S, Chebib M, Johnston GAR, Hanrahan JR.

Br J Pharmacol. 2017 Jul;174(13):1881-1894. doi: 10.1111/bph.13768. Epub 2017 Apr 12. Review.


Differential Contribution of Subunit Interfaces to α9α10 Nicotinic Acetylcholine Receptor Function.

Boffi JC, Marcovich I, Gill-Thind JK, Corradi J, Collins T, Lipovsek MM, Moglie M, Plazas PV, Craig PO, Millar NS, Bouzat C, Elgoyhen AB.

Mol Pharmacol. 2017 Mar;91(3):250-262. doi: 10.1124/mol.116.107482. Epub 2017 Jan 9. Erratum in: Mol Pharmacol. 2017 May;91(5):437.


Disruption of a putative intersubunit electrostatic bond enhances agonist efficacy at the human α1 glycine receptor.

Welsh BT, Todorovic J, Kirson D, Allen HM, Bayly MD, Mihic SJ.

Brain Res. 2017 Feb 15;1657:148-155. doi: 10.1016/j.brainres.2016.11.024. Epub 2016 Dec 5.


Discovery, synthesis, biological evaluation and structure-based optimization of novel piperidine derivatives as acetylcholine-binding protein ligands.

Shen J, Yang XC, Yu MC, Xiao L, Zhang XJ, Sun HJ, Chen H, Pan GX, Yan YR, Wang SC, Li W, Zhou L, Xie Q, Yu LQ, Wang YH, Shao LM.

Acta Pharmacol Sin. 2017 Jan;38(1):146-155. doi: 10.1038/aps.2016.124. Epub 2016 Dec 5.


High-Affinity α-Conotoxin PnIA Analogs Designed on the Basis of the Protein Surface Topography Method.

Kasheverov IE, Chugunov AO, Kudryavtsev DS, Ivanov IA, Zhmak MN, Shelukhina IV, Spirova EN, Tabakmakher VM, Zelepuga EA, Efremov RG, Tsetlin VI.

Sci Rep. 2016 Nov 14;6:36848. doi: 10.1038/srep36848.


Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.

Nys M, Wijckmans E, Farinha A, Yoluk Ö, Andersson M, Brams M, Spurny R, Peigneur S, Tytgat J, Lindahl E, Ulens C.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6696-E6703. Epub 2016 Oct 10.


Molecular recognition at cholinergic synapses: acetylcholine versus choline.

Bruhova I, Auerbach A.

J Physiol. 2017 Feb 15;595(4):1253-1261. doi: 10.1113/JP273291. Epub 2016 Dec 12.


Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs.

Lin B, Xiang S, Li M.

Mar Drugs. 2016 Oct 11;14(10). pii: E173. Review.


Mechanism of Allosteric Modulation of the Cys-loop Receptors.

Chang Y, Huang Y, Whiteaker P.

Pharmaceuticals (Basel). 2010 Aug 12;3(8):2592-2609. Review.


Crystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound α2 homopentamer.

Kouvatsos N, Giastas P, Chroni-Tzartou D, Poulopoulou C, Tzartos SJ.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9635-40. doi: 10.1073/pnas.1602619113. Epub 2016 Aug 4.


Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors.

Burgos CF, Yévenes GE, Aguayo LG.

Mol Pharmacol. 2016 Sep;90(3):318-25. doi: 10.1124/mol.116.105726. Epub 2016 Jul 11. Review.


Structural Studies of GABAA Receptor Binding Sites: Which Experimental Structure Tells us What?

Puthenkalam R, Hieckel M, Simeone X, Suwattanasophon C, Feldbauer RV, Ecker GF, Ernst M.

Front Mol Neurosci. 2016 Jun 16;9:44. doi: 10.3389/fnmol.2016.00044. eCollection 2016.


Escherichia coli Protein Expression System for Acetylcholine Binding Proteins (AChBPs).

Abraham N, Paul B, Ragnarsson L, Lewis RJ.

PLoS One. 2016 Jun 15;11(6):e0157363. doi: 10.1371/journal.pone.0157363. eCollection 2016.


Dihydrostreptomycin Directly Binds to, Modulates, and Passes through the MscL Channel Pore.

Wray R, Iscla I, Gao Y, Li H, Wang J, Blount P.

PLoS Biol. 2016 Jun 9;14(6):e1002473. doi: 10.1371/journal.pbio.1002473. eCollection 2016 Jun.


Structural correlates of affinity in fetal versus adult endplate nicotinic receptors.

Nayak TK, Chakraborty S, Zheng W, Auerbach A.

Nat Commun. 2016 Apr 22;7:11352. doi: 10.1038/ncomms11352.


Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues.

Wijckmans E, Nys M, Debaveye S, Brams M, Pardon E, Willegems K, Bertrand D, Steyaert J, Efremov R, Ulens C.

PLoS One. 2016 Mar 21;11(3):e0151183. doi: 10.1371/journal.pone.0151183. eCollection 2016.


Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)3(β2)2 nAChR-Selective Positive Allosteric Modulator.

Hamouda AK, Deba F, Wang ZJ, Cohen JB.

Mol Pharmacol. 2016 May;89(5):575-84. doi: 10.1124/mol.116.103341. Epub 2016 Mar 14.


Introduced Amino Terminal Epitopes Can Reduce Surface Expression of Neuronal Nicotinic Receptors.

Bracamontes JR, Akk G, Steinbach JH.

PLoS One. 2016 Mar 10;11(3):e0151071. doi: 10.1371/journal.pone.0151071. eCollection 2016.

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