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Items: 1 to 20 of 147


The modification of natural products for medical use.

Guo Z.

Acta Pharm Sin B. 2017 Mar;7(2):119-136. doi: 10.1016/j.apsb.2016.06.003. Epub 2016 Nov 25. Review.


Zhibitai and low-dose atorvastatin reduce blood lipids and inflammation in patients with coronary artery disease.

Zhao Y, Peng R, Zhao W, Liu Q, Guo Y, Zhao S, Xu D.

Medicine (Baltimore). 2017 Feb;96(7):e6104. doi: 10.1097/MD.0000000000006104.


Lepidopteran HMG-CoA reductase is a potential selective target for pest control.

Li YM, Kai ZP, Huang J, Tobe SS.

PeerJ. 2017 Jan 19;5:e2881. doi: 10.7717/peerj.2881. eCollection 2017.


GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary.

Jiang C, Diao F, Sang YJ, Xu N, Zhu RL, Wang XX, Chen Z, Tao WW, Yao B, Sun HX, Huang XX, Xue B, Li CJ.

PLoS Genet. 2017 Jan 10;13(1):e1006535. doi: 10.1371/journal.pgen.1006535. eCollection 2017 Jan.


Pleiotropic Effects of Statins on the Cardiovascular System.

Oesterle A, Laufs U, Liao JK.

Circ Res. 2017 Jan 6;120(1):229-243. doi: 10.1161/CIRCRESAHA.116.308537. Review.


Natural products from filamentous fungi and production by heterologous expression.

Alberti F, Foster GD, Bailey AM.

Appl Microbiol Biotechnol. 2017 Jan;101(2):493-500. doi: 10.1007/s00253-016-8034-2. Epub 2016 Dec 13. Review.


Targeting Inflammation in Cancer Prevention and Therapy.

Todoric J, Antonucci L, Karin M.

Cancer Prev Res (Phila). 2016 Dec;9(12):895-905. Epub 2016 Nov 10. Review.


Statin use decreases coagulation in users of vitamin K antagonists.

van Rein N, Biedermann JS, Bonafacio SM, Kruip MJ, van der Meer FJ, Lijfering WM.

Eur J Clin Pharmacol. 2016 Dec;72(12):1441-1447. Epub 2016 Oct 5.


Cardiovascular Disease Chemogenomics Knowledgebase-guided Target Identification and Drug Synergy Mechanism Study of an Herbal Formula.

Zhang H, Ma S, Feng Z, Wang D, Li C, Cao Y, Chen X, Liu A, Zhu Z, Zhang J, Zhang G, Chai Y, Wang L, Xie XQ.

Sci Rep. 2016 Sep 28;6:33963. doi: 10.1038/srep33963.


Statins dose-dependently exert a chemopreventive effect against lung cancer in COPD patients: a population-based cohort study.

Liu JC, Yang TY, Hsu YP, Hao WR, Kao PF, Sung LC, Chen CC, Wu SY.

Oncotarget. 2016 Sep 13;7(37):59618-59629. doi: 10.18632/oncotarget.11162.


Low use of statins for secondary prevention in primary care: a survey in a northern Swedish population.

Nilsson G, Samuelsson E, Söderström L, Mooe T.

BMC Fam Pract. 2016 Aug 11;17(1):110. doi: 10.1186/s12875-016-0505-0.


Hypolipidemic effects of HVC1 in a high cholesterol diet‑induced rat model of hyperlipidemia.

Kim CY, Chung KS, Cheon SY, Lee K, Ham I, Choi HY, Cho YB, Cho BH, Mok SY, An HJ.

Mol Med Rep. 2016 Oct;14(4):3152-8. doi: 10.3892/mmr.2016.5615. Epub 2016 Aug 9.


Effect of Statins on the Nanomechanical Properties of Supported Lipid Bilayers.

Redondo-Morata L, Lea Sanford R, Andersen OS, Scheuring S.

Biophys J. 2016 Jul 26;111(2):363-72. doi: 10.1016/j.bpj.2016.06.016.


Combined Effects of Rosuvastatin and Exercise on Gene Expression of Key Molecules Involved in Cholesterol Metabolism in Ovariectomized Rats.

Ngo Sock ET, Mayer G, Lavoie JM.

PLoS One. 2016 Jul 21;11(7):e0159550. doi: 10.1371/journal.pone.0159550. eCollection 2016.


Low-density lipoprotein receptors play an important role in the inhibition of prostate cancer cell proliferation by statins.

Furuya Y, Sekine Y, Kato H, Miyazawa Y, Koike H, Suzuki K.

Prostate Int. 2016 Jun;4(2):56-60. doi: 10.1016/j.prnil.2016.02.003. Epub 2016 Mar 4.


AutoSite: an automated approach for pseudo-ligands prediction-from ligand-binding sites identification to predicting key ligand atoms.

Ravindranath PA, Sanner MF.

Bioinformatics. 2016 Oct 15;32(20):3142-3149. Epub 2016 Jun 26.


Is There Potential for Repurposing Statins as Novel Antimicrobials?

Hennessy E, Adams C, Reen FJ, O'Gara F.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5111-21. doi: 10.1128/AAC.00192-16. Print 2016 Sep. Review.


PEGylated IL-10 Activates Kupffer Cells to Control Hypercholesterolemia.

Chan IH, Van Hoof D, Abramova M, Bilardello M, Mar E, Jorgensen B, McCauley S, Bal H, Oft M, Van Vlasselaer P, Mumm JB.

PLoS One. 2016 Jun 14;11(6):e0156229. doi: 10.1371/journal.pone.0156229. eCollection 2016.


Harnessing Fluorine-Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs.

Bauer MR, Jones RN, Baud MG, Wilcken R, Boeckler FM, Fersht AR, Joerger AC, Spencer J.

ACS Chem Biol. 2016 Aug 19;11(8):2265-74. doi: 10.1021/acschembio.6b00315. Epub 2016 Jun 21.

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