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Items: 1 to 20 of 150


Zonda is a novel early component of the autophagy pathway in Drosophila.

Melani M, Valko A, Romero NM, Aguilera MO, Acevedo JM, Bhujabal Z, Perez-Perri J, de la Riva-Carrasco RV, Katz MJ, Sorianello E, D'Alessio C, Juhász G, Johansen T, Colombo MI, Wappner P.

Mol Biol Cell. 2017 Nov 1;28(22):3070-3081. doi: 10.1091/mbc.E16-11-0767. Epub 2017 Sep 13.


Lymphangioleiomyomatosis: A Monogenic Model of Malignancy.

Krymskaya VP, McCormack FX.

Annu Rev Med. 2017 Jan 14;68:69-83. doi: 10.1146/annurev-med-050715-104245. Review.


Drugging the addict: non-oncogene addiction as a target for cancer therapy.

Nagel R, Semenova EA, Berns A.

EMBO Rep. 2016 Nov;17(11):1516-1531. Epub 2016 Oct 4. Review.


Inability to activate Rac1-dependent forgetting contributes to behavioral inflexibility in mutants of multiple autism-risk genes.

Dong T, He J, Wang S, Wang L, Cheng Y, Zhong Y.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7644-9. doi: 10.1073/pnas.1602152113. Epub 2016 Jun 22.


A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing.

Danielsen ET, Moeller ME, Yamanaka N, Ou Q, Laursen JM, Soenderholm C, Zhuo R, Phelps B, Tang K, Zeng J, Kondo S, Nielsen CH, Harvald EB, Faergeman NJ, Haley MJ, O'Connor KA, King-Jones K, O'Connor MB, Rewitz KF.

Dev Cell. 2016 Jun 20;37(6):558-70. doi: 10.1016/j.devcel.2016.05.015.


Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations From the 2015 Strategic Planning Conference.

Sahin M, Henske EP, Manning BD, Ess KC, Bissler JJ, Klann E, Kwiatkowski DJ, Roberds SL, Silva AJ, Hillaire-Clarke CS, Young LR, Zervas M, Mamounas LA; Tuberous Sclerosis Complex Working Group to Update the Research Plan.

Pediatr Neurol. 2016 Jul;60:1-12. doi: 10.1016/j.pediatrneurol.2016.03.015. Epub 2016 Apr 2.


The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function.

Cai W, Wei Y, Jarnik M, Reich J, Lilly MA.

PLoS Genet. 2016 May 11;12(5):e1006036. doi: 10.1371/journal.pgen.1006036. eCollection 2016 May.


The legacy of Drosophila imaginal discs.

Beira JV, Paro R.

Chromosoma. 2016 Sep;125(4):573-92. doi: 10.1007/s00412-016-0595-4. Epub 2016 May 7. Review.


mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy.

Taneike M, Nishida K, Omiya S, Zarrinpashneh E, Misaka T, Kitazume-Taneike R, Austin R, Takaoka M, Yamaguchi O, Gambello MJ, Shah AM, Otsu K.

PLoS One. 2016 Mar 29;11(3):e0152628. doi: 10.1371/journal.pone.0152628. eCollection 2016.


Modeling congenital disease and inborn errors of development in Drosophila melanogaster.

Moulton MJ, Letsou A.

Dis Model Mech. 2016 Mar;9(3):253-69. doi: 10.1242/dmm.023564. Review.


Cdk4 functions in multiple cell types to control Drosophila intestinal stem cell proliferation and differentiation.

Adlesic M, Frei C, Frew IJ.

Biol Open. 2016 Feb 15;5(3):237-51. doi: 10.1242/bio.016584.


period-Regulated Feeding Behavior and TOR Signaling Modulate Survival of Infection.

Allen VW, O'Connor RM, Ulgherait M, Zhou CG, Stone EF, Hill VM, Murphy KR, Canman JC, Ja WW, Shirasu-Hiza MM.

Curr Biol. 2016 Jan 25;26(2):184-94. doi: 10.1016/j.cub.2015.11.051. Epub 2015 Dec 31.


Scaling the Drosophila Wing: TOR-Dependent Target Gene Access by the Hippo Pathway Transducer Yorkie.

Parker J, Struhl G.

PLoS Biol. 2015 Oct 16;13(10):e1002274. doi: 10.1371/journal.pbio.1002274. eCollection 2015 Oct.


A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development.

Jones I, Hägglund AC, Törnqvist G, Nord C, Ahlgren U, Carlsson L.

Dis Model Mech. 2015 Dec;8(12):1517-29. doi: 10.1242/dmm.021972. Epub 2015 Oct 8.


Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi.

Housden BE, Valvezan AJ, Kelley C, Sopko R, Hu Y, Roesel C, Lin S, Buckner M, Tao R, Yilmazel B, Mohr SE, Manning BD, Perrimon N.

Sci Signal. 2015 Sep 8;8(393):rs9. doi: 10.1126/scisignal.aab3729.


Dally Proteoglycan Mediates the Autonomous and Nonautonomous Effects on Tissue Growth Caused by Activation of the PI3K and TOR Pathways.

Ferreira A, Milán M.

PLoS Biol. 2015 Aug 27;13(8):e1002239. doi: 10.1371/journal.pbio.1002239. eCollection 2015 Aug.


Cyclin G Functions as a Positive Regulator of Growth and Metabolism in Drosophila.

Fischer P, La Rosa MK, Schulz A, Preiss A, Nagel AC.

PLoS Genet. 2015 Aug 14;11(8):e1005440. doi: 10.1371/journal.pgen.1005440. eCollection 2015 Aug.


The Systemic Control of Growth.

Boulan L, Milán M, Léopold P.

Cold Spring Harb Perspect Biol. 2015 Aug 10;7(12). pii: a019117. doi: 10.1101/cshperspect.a019117. Review.


Biological Scaling Problems and Solutions in Amphibians.

Levy DL, Heald R.

Cold Spring Harb Perspect Biol. 2015 Aug 10;8(1):a019166. doi: 10.1101/cshperspect.a019166. Review.


Regulation of mTORC1 by PI3K signaling.

Dibble CC, Cantley LC.

Trends Cell Biol. 2015 Sep;25(9):545-55. doi: 10.1016/j.tcb.2015.06.002. Epub 2015 Jul 6. Review.

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