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Items: 1 to 20 of 22


Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma.

Qin EY, Cooper DD, Abbott KL, Lennon J, Nagaraja S, Mackay A, Jones C, Vogel H, Jackson PK, Monje M.

Cell. 2017 Aug 24;170(5):845-859.e19. doi: 10.1016/j.cell.2017.07.016. Epub 2017 Aug 17.


LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.

Lagoutte E, Villeneuve C, Lafanechère L, Wells CM, Jones GE, Chavrier P, Rossé C.

Sci Rep. 2016 Apr 27;6:24925. doi: 10.1038/srep24925.


Afzelin exhibits anti-cancer activity against androgen-sensitive LNCaP and androgen-independent PC-3 prostate cancer cells through the inhibition of LIM domain kinase 1.

Zhu KC, Sun JM, Shen JG, Jin JZ, Liu F, Xu XL, Chen L, Liu LT, Lv JJ.

Oncol Lett. 2015 Oct;10(4):2359-2365. Epub 2015 Aug 18.


Myotonic dystrophy kinase-related Cdc42-binding kinases (MRCK), the ROCK-like effectors of Cdc42 and Rac1.

Zhao Z, Manser E.

Small GTPases. 2015;6(2):81-8. doi: 10.1080/21541248.2014.1000699. Epub 2015 Jun 19. Review.


Molecular pathways: targeting the kinase effectors of RHO-family GTPases.

Prudnikova TY, Rawat SJ, Chernoff J.

Clin Cancer Res. 2015 Jan 1;21(1):24-9. doi: 10.1158/1078-0432.CCR-14-0827. Epub 2014 Oct 21. Erratum in: Clin Cancer Res. 2015 Apr 1;21(7):1772.


Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics.

Lee IC, Leung T, Tan I.

J Biol Chem. 2014 Sep 26;289(39):26989-7003. doi: 10.1074/jbc.M114.588079. Epub 2014 Aug 8.


Interleukin-1β-induced Wnt5a enhances human corneal endothelial cell migration through regulation of Cdc42 and RhoA.

Lee JG, Heur M.

Mol Cell Biol. 2014 Sep 15;34(18):3535-45. doi: 10.1128/MCB.01572-13. Epub 2014 Jul 14.


The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer.

Unbekandt M, Olson MF.

J Mol Med (Berl). 2014 Mar;92(3):217-25. doi: 10.1007/s00109-014-1133-6. Epub 2014 Feb 20. Review.


Functions of cofilin in cell locomotion and invasion.

Bravo-Cordero JJ, Magalhaes MA, Eddy RJ, Hodgson L, Condeelis J.

Nat Rev Mol Cell Biol. 2013 Jul;14(7):405-15. doi: 10.1038/nrm3609. Epub 2013 Jun 19. Review.


Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.

Rosário M, Schuster S, Jüttner R, Parthasarathy S, Tarabykin V, Birchmeier W.

Genes Dev. 2012 Aug 1;26(15):1743-57. doi: 10.1101/gad.191593.112. Epub 2012 Jul 18.


The cytoskeletal regulator Genghis khan is required for columnar target specificity in the Drosophila visual system.

Gontang AC, Hwa JJ, Mast JD, Schwabe T, Clandinin TR.

Development. 2011 Nov;138(22):4899-909. doi: 10.1242/dev.069930. Epub 2011 Oct 17.


Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression.

McConnell BV, Koto K, Gutierrez-Hartmann A.

Mol Cancer. 2011 Jun 18;10:75. doi: 10.1186/1476-4598-10-75.


Distinct effects of contraction agonists on the phosphorylation state of cofilin in pulmonary artery smooth muscle.

Dai YP, Bongalon S, Mutafova-Yambolieva VN, Yamboliev IA.

Adv Pharmacol Sci. 2008;2008:362741. doi: 10.1155/2008/362741. Epub 2007 Nov 6.


Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin activation and RhoA inhibition.

Huang ZH, Wang Y, Su ZD, Geng JG, Chen YZ, Yuan XB, He C.

J Cell Sci. 2011 Jan 15;124(Pt 2):186-97. doi: 10.1242/jcs.071357.


Dual roles for RHOA/RHO-kinase in the regulated trafficking of a voltage-sensitive potassium channel.

Stirling L, Williams MR, Morielli AD.

Mol Biol Cell. 2009 Jun;20(12):2991-3002. doi: 10.1091/mbc.E08-10-1074. Epub 2009 Apr 29.


Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response.

Thirone AC, Speight P, Zulys M, Rotstein OD, Szászi K, Pedersen SF, Kapus A.

Am J Physiol Cell Physiol. 2009 Mar;296(3):C463-75. doi: 10.1152/ajpcell.00467.2008. Epub 2008 Dec 24.


Pathways leading to phosphorylation of p450c17 and to the posttranslational regulation of androgen biosynthesis.

Tee MK, Dong Q, Miller WL.

Endocrinology. 2008 May;149(5):2667-77. doi: 10.1210/en.2007-1527. Epub 2008 Jan 10.


The cofilin pathway in breast cancer invasion and metastasis.

Wang W, Eddy R, Condeelis J.

Nat Rev Cancer. 2007 Jun;7(6):429-40. Review.


The Rho kinases I and II regulate different aspects of myosin II activity.

Yoneda A, Multhaupt HA, Couchman JR.

J Cell Biol. 2005 Aug 1;170(3):443-53. Epub 2005 Jul 25.


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