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Items: 1 to 20 of 24

1.

Epigenetic impact of endocrine disrupting chemicals on lipid homeostasis and atherosclerosis: a pregnane X receptor-centric view.

Helsley RN, Zhou C.

Environ Epigenet. 2017 Oct 1;3(4). pii: dvx017. doi: 10.1093/eep/dvx017. Epub 2017 Oct 23.

2.

Evaluation of a novel PXR-knockout in HepaRG cells.

Williamson B, Lorbeer M, Mitchell MD, Brayman TG, Riley RJ.

Pharmacol Res Perspect. 2016 Sep 21;4(5):e00264. eCollection 2016 Oct.

3.

Insights into CYP2B6-mediated drug-drug interactions.

Hedrich WD, Hassan HE, Wang H.

Acta Pharm Sin B. 2016 Sep;6(5):413-425. Epub 2016 Aug 9. Review.

4.

Anti-inflammatory and Immunomodulatory Effects of Antibiotics and Their Use in Dermatology.

Pradhan S, Madke B, Kabra P, Singh AL.

Indian J Dermatol. 2016 Sep-Oct;61(5):469-81. doi: 10.4103/0019-5154.190105. Review.

5.

Novel functions of PXR in cardiometabolic disease.

Zhou C.

Biochim Biophys Acta. 2016 Sep;1859(9):1112-1120. doi: 10.1016/j.bbagrm.2016.02.015. Epub 2016 Feb 26. Review.

7.

Jaundice associated pruritis: a review of pathophysiology and treatment.

Bassari R, Koea JB.

World J Gastroenterol. 2015 Feb 7;21(5):1404-13. doi: 10.3748/wjg.v21.i5.1404. Review.

8.
9.

Chimeric mice with humanized livers: a unique tool for in vivo and in vitro enzyme induction studies.

Kakuni M, Yamasaki C, Tachibana A, Yoshizane Y, Ishida Y, Tateno C.

Int J Mol Sci. 2013 Dec 20;15(1):58-74. doi: 10.3390/ijms15010058.

10.

Nutrigenomics and cancer.

Ardekani AM, Jabbari S.

Avicenna J Med Biotechnol. 2009 Apr;1(1):9-17.

11.

Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor.

Fraccalvieri D, Soshilov AA, Karchner SI, Franks DG, Pandini A, Bonati L, Hahn ME, Denison MS.

Biochemistry. 2013 Jan 29;52(4):714-25. doi: 10.1021/bi301457f. Epub 2013 Jan 14.

12.

Cytochrome P450 regulation by α-tocopherol in Pxr-null and PXR-humanized mice.

Johnson CH, Bonzo JA, Cheng J, Krausz KW, Kang DW, Luecke H, Idle JR, Gonzalez FJ.

Drug Metab Dispos. 2013 Feb;41(2):406-13. doi: 10.1124/dmd.112.048009. Epub 2012 Nov 16.

13.

The novel antibacterial compound walrycin A induces human PXR transcriptional activity.

Berthier A, Oger F, Gheeraert C, Boulahtouf A, Le Guével R, Balaguer P, Staels B, Salbert G, Lefebvre P.

Toxicol Sci. 2012 May;127(1):225-35. doi: 10.1093/toxsci/kfs073. Epub 2012 Feb 7.

14.

Species difference in the regulation of cytochrome P450 2S1: lack of induction in rats by the aryl hydrocarbon receptor agonist PCB126.

Wang B, Robertson LW, Wang K, Ludewig G.

Xenobiotica. 2011 Dec;41(12):1031-43. doi: 10.3109/00498254.2011.603763. Epub 2011 Oct 4.

15.

FXR and PXR: potential therapeutic targets in cholestasis.

Jonker JW, Liddle C, Downes M.

J Steroid Biochem Mol Biol. 2012 Jul;130(3-5):147-58. doi: 10.1016/j.jsbmb.2011.06.012. Epub 2011 Jul 20. Review.

16.

Identification of clinically used drugs that activate pregnane X receptors.

Shukla SJ, Sakamuru S, Huang R, Moeller TA, Shinn P, Vanleer D, Auld DS, Austin CP, Xia M.

Drug Metab Dispos. 2011 Jan;39(1):151-9. doi: 10.1124/dmd.110.035105. Epub 2010 Oct 21. Erratum in: Drug Metab Dispos. 2011 Feb;39(2):351.

17.
18.

Evaluation of an in vitro toxicogenetic mouse model for hepatotoxicity.

Martinez SM, Bradford BU, Soldatow VY, Kosyk O, Sandot A, Witek R, Kaiser R, Stewart T, Amaral K, Freeman K, Black C, LeCluyse EL, Ferguson SS, Rusyn I.

Toxicol Appl Pharmacol. 2010 Dec 15;249(3):208-16. doi: 10.1016/j.taap.2010.09.012. Epub 2010 Sep 24.

19.

Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.

Tolson AH, Wang H.

Adv Drug Deliv Rev. 2010 Oct 30;62(13):1238-49. doi: 10.1016/j.addr.2010.08.006. Epub 2010 Aug 17. Review.

20.

The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.

Zhou C, Verma S, Blumberg B.

Nucl Recept Signal. 2009;7:e001. doi: 10.1621/nrs.07001. Epub 2009 Jan 16. Review.

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