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Items: 1 to 20 of 116

1.

Obstacles to Brain Tumor Therapy: Key ABC Transporters.

Wijaya J, Fukuda Y, Schuetz JD.

Int J Mol Sci. 2017 Nov 27;18(12). pii: E2544. doi: 10.3390/ijms18122544. Review.

2.

Bortezomib, carfilzomib and ixazomib do not mediate relevant transporter-based drug-drug interactions.

Clemens J, Welti L, Schäfer J, Seckinger A, Burhenne J, Theile D, Weiss J.

Oncol Lett. 2017 Sep;14(3):3185-3192. doi: 10.3892/ol.2017.6560. Epub 2017 Jul 8.

3.

Dynamic equilibrium on DNA defines transcriptional regulation of a multidrug binding transcriptional repressor, LmrR.

Takeuchi K, Imai M, Shimada I.

Sci Rep. 2017 Mar 21;7(1):267. doi: 10.1038/s41598-017-00257-x.

4.

Constitutive androstane receptor regulates the intestinal mucosal response to injury.

Hudson GM, Flannigan KL, Erickson SL, Vicentini FA, Zamponi A, Hirota CL, Alston L, Altier C, Ghosh S, Rioux KP, Mani S, Chang TK, Hirota SA.

Br J Pharmacol. 2017 Jun;174(12):1857-1871. doi: 10.1111/bph.13787. Epub 2017 Apr 19.

PMID:
28320072
5.

Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin.

Chedik L, Bruyere A, Le Vee M, Stieger B, Denizot C, Parmentier Y, Potin S, Fardel O.

PLoS One. 2017 Jan 18;12(1):e0169480. doi: 10.1371/journal.pone.0169480. eCollection 2017.

6.

Drug Transporter Expression and Activity in Human Hepatoma HuH-7 Cells.

Jouan E, Le Vée M, Denizot C, Parmentier Y, Fardel O.

Pharmaceutics. 2016 Dec 28;9(1). pii: E3. doi: 10.3390/pharmaceutics9010003.

7.

Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters.

Matthaei J, Tzvetkov MV, Gal V, Sachse-Seeboth C, Sehrt D, Hjelmborg JB, Hofmann U, Schwab M, Kerb R, Brockmöller J.

Genome Med. 2016 Nov 8;8(1):119.

8.

The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat.

Lowes S, Haslam IS, Fihn BM, Hilgendorf C, Karlsson JE, Simmons NL, Ungell AL.

Pharmaceutics. 2010 Mar 15;2(1):61-77.

9.

Insights into CYP2B6-mediated drug-drug interactions.

Hedrich WD, Hassan HE, Wang H.

Acta Pharm Sin B. 2016 Sep;6(5):413-425. Epub 2016 Aug 9. Review.

10.

Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes.

Benson EA, Eadon MT, Desta Z, Liu Y, Lin H, Burgess KS, Segar MW, Gaedigk A, Skaar TC.

Front Pharmacol. 2016 Apr 26;7:111. doi: 10.3389/fphar.2016.00111. eCollection 2016.

11.

Induction of P-glycoprotein expression and activity by Aconitum alkaloids: Implication for clinical drug-drug interactions.

Wu J, Lin N, Li F, Zhang G, He S, Zhu Y, Ou R, Li N, Liu S, Feng L, Liu L, Liu Z, Lu L.

Sci Rep. 2016 May 3;6:25343. doi: 10.1038/srep25343.

13.

Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity.

Pasquel D, Doricakova A, Li H, Kortagere S, Krasowski MD, Biswas A, Walton WG, Redinbo MR, Dvorak Z, Mani S.

Biochim Biophys Acta. 2016 Sep;1859(9):1155-1169. doi: 10.1016/j.bbagrm.2016.01.006. Epub 2016 Feb 23.

14.

The pregnane X receptor in tuberculosis therapeutics.

Shehu AI, Li G, Xie W, Ma X.

Expert Opin Drug Metab Toxicol. 2016;12(1):21-30. doi: 10.1517/17425255.2016.1121381. Epub 2015 Dec 5. Review.

15.

Activation status of the pregnane X receptor influences vemurafenib availability in humanized mouse models.

MacLeod AK, McLaughlin LA, Henderson CJ, Wolf CR.

Cancer Res. 2015 Nov 1;75(21):4573-81. doi: 10.1158/0008-5472.CAN-15-1454. Epub 2015 Sep 11.

16.

In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice.

Yasuda K, Cline C, Lin YS, Scheib R, Ganguly S, Thirumaran RK, Chaudhry A, Kim RB, Schuetz EG.

Drug Metab Dispos. 2015 Nov;43(11):1646-54. doi: 10.1124/dmd.115.065078. Epub 2015 Aug 17.

17.

Casein Kinase 2 (CK2)-mediated Phosphorylation of Hsp90β as a Novel Mechanism of Rifampin-induced MDR1 Expression.

Kim SW, Hasanuzzaman M, Cho M, Heo YR, Ryu MJ, Ha NY, Park HJ, Park HY, Shin JG.

J Biol Chem. 2015 Jul 3;290(27):17029-40. doi: 10.1074/jbc.M114.624106. Epub 2015 May 20.

18.

Transcriptional Regulation of CYP3A4/2B6/2C9 Mediated via Nuclear Receptor PXR by Helicid and Its Metabolites.

Chen Q, Xie HT, Li Y, Wang G, Xu Z, Pu ZC, Hu H.

Evid Based Complement Alternat Med. 2015;2015:797496. doi: 10.1155/2015/797496. Epub 2015 Apr 22.

19.

Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicity.

Rigalli JP, Ciriaci N, Arias A, Ceballos MP, Villanueva SS, Luquita MG, Mottino AD, Ghanem CI, Catania VA, Ruiz ML.

PLoS One. 2015 Mar 17;10(3):e0119502. doi: 10.1371/journal.pone.0119502. eCollection 2015.

20.

Indirect protein quantification of drug-transforming enzymes using peptide group-specific immunoaffinity enrichment and mass spectrometry.

Weiß F, Schnabel A, Planatscher H, van den Berg BH, Serschnitzki B, Nuessler AK, Thasler WE, Weiss TS, Reuss M, Stoll D, Templin MF, Joos TO, Marcus K, Poetz O.

Sci Rep. 2015 Mar 4;5:8759. doi: 10.1038/srep08759.

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