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Items: 17

1.

The protein phosphatase 2A regulatory subunit B56γ mediates suppression of T cell receptor (TCR)-induced nuclear factor-κB (NF-κB) activity.

Breuer R, Becker MS, Brechmann M, Mock T, Arnold R, Krammer PH.

J Biol Chem. 2014 May 23;289(21):14996-5004. doi: 10.1074/jbc.M113.533547. Epub 2014 Apr 9.

2.

The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1.

Wang H, Chen Y, Lin P, Li L, Zhou G, Liu G, Logsdon C, Jin J, Abbruzzese JL, Tan TH, Wang H.

J Biol Chem. 2014 Feb 14;289(7):4009-17. doi: 10.1074/jbc.M113.520106. Epub 2013 Dec 20.

3.

Germinal center kinases in immune regulation.

Yin H, Shi Z, Jiao S, Chen C, Wang W, Greene MI, Zhou Z.

Cell Mol Immunol. 2012 Nov;9(6):439-45. doi: 10.1038/cmi.2012.30. Epub 2012 Sep 10. Review.

4.
6.

Down-regulation of B cell receptor signaling by hematopoietic progenitor kinase 1 (HPK1)-mediated phosphorylation and ubiquitination of activated B cell linker protein (BLNK).

Wang X, Li JP, Kuo HK, Chiu LL, Dement GA, Lan JL, Chen DY, Yang CY, Hu H, Tan TH.

J Biol Chem. 2012 Mar 30;287(14):11037-48. doi: 10.1074/jbc.M111.310946. Epub 2012 Feb 10.

7.

The SLP-76 Src homology 2 domain is required for T cell development and activation.

Burns JC, Corbo E, Degen J, Gohil M, Anterasian C, Schraven B, Koretzky GA, Kliche S, Jordan MS.

J Immunol. 2011 Nov 1;187(9):4459-66. doi: 10.4049/jimmunol.0903379. Epub 2011 Sep 26.

8.

Pro- and anti-apoptotic CD95 signaling in T cells.

Paulsen M, Janssen O.

Cell Commun Signal. 2011 Apr 8;9:7. doi: 10.1186/1478-811X-9-7.

9.

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells.

Neumann L, Pforr C, Beaudouin J, Pappa A, Fricker N, Krammer PH, Lavrik IN, Eils R.

Mol Syst Biol. 2010;6:352. doi: 10.1038/msb.2010.6. Epub 2010 Mar 9.

10.

Caspases and kinases in a death grip.

Kurokawa M, Kornbluth S.

Cell. 2009 Sep 4;138(5):838-54. doi: 10.1016/j.cell.2009.08.021. Review.

11.

Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells.

Brenner D, Brechmann M, Röhling S, Tapernoux M, Mock T, Winter D, Lehmann WD, Kiefer F, Thome M, Krammer PH, Arnold R.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14508-13. doi: 10.1073/pnas.0900457106. Epub 2009 Aug 11.

12.

Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancer.

Wang H, Song X, Logsdon C, Zhou G, Evans DB, Abbruzzese JL, Hamilton SR, Tan TH, Wang H.

Cancer Res. 2009 Feb 1;69(3):1063-70. doi: 10.1158/0008-5472.CAN-08-1751. Epub 2009 Jan 13.

13.

Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death.

Brenner D, Golks A, Kiefer F, Krammer PH, Arnold R.

EMBO J. 2005 Dec 21;24(24):4279-90. Epub 2005 Dec 8.

14.

Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1.

Arnold R, Patzak IM, Neuhaus B, Vancauwenbergh S, Veillette A, Van Lint J, Kiefer F.

Mol Cell Biol. 2005 Mar;25(6):2364-83.

15.

Human T lymphotropic virus type-1 p30II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes.

Michael B, Nair AM, Hiraragi H, Shen L, Feuer G, Boris-Lawrie K, Lairmore MD.

Retrovirology. 2004 Nov 23;1:39.

16.

B cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1.

Tsuji S, Okamoto M, Yamada K, Okamoto N, Goitsuka R, Arnold R, Kiefer F, Kitamura D.

J Exp Med. 2001 Aug 20;194(4):529-39.

17.

Synergistic regulation of immunoreceptor signaling by SLP-76-related adaptor Clnk and serine/threonine protein kinase HPK-1.

Yu J, Riou C, Davidson D, Minhas R, Robson JD, Julius M, Arnold R, Kiefer F, Veillette A.

Mol Cell Biol. 2001 Sep;21(18):6102-12.

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