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Items: 1 to 20 of 85


Metformin: a review of its potential indications.

Wang YW, He SJ, Feng X, Cheng J, Luo YT, Tian L, Huang Q.

Drug Des Devel Ther. 2017 Aug 22;11:2421-2429. doi: 10.2147/DDDT.S141675. eCollection 2017. Review.


ROS Production and ERK Activity Are Involved in the Effects of d-β-Hydroxybutyrate and Metformin in a Glucose Deficient Condition.

Lamichhane S, Bastola T, Pariyar R, Lee ES, Lee HS, Lee DH, Seo J.

Int J Mol Sci. 2017 Mar 21;18(3). pii: E674. doi: 10.3390/ijms18030674.


Obesity-Related Digestive Diseases and Their Pathophysiology.

Nam SY.

Gut Liver. 2017 May 15;11(3):323-334. doi: 10.5009/gnl15557. Review.


PPAR Gamma in Neuroblastoma: The Translational Perspectives of Hypoglycemic Drugs.

Vella S, Conaldi PG, Florio T, Pagano A.

PPAR Res. 2016;2016:3038164. Epub 2016 Oct 5. Review.


Metformin inhibits estrogen-dependent endometrial cancer cell growth by activating the AMPK-FOXO1 signal pathway.

Zou J, Hong L, Luo C, Li Z, Zhu Y, Huang T, Zhang Y, Yuan H, Hu Y, Wen T, Zhuang W, Cai B, Zhang X, Huang J, Cheng J.

Cancer Sci. 2016 Dec;107(12):1806-1817. doi: 10.1111/cas.13083. Epub 2016 Nov 25.


Metformin Protects Against Cisplatin-Induced Tubular Cell Apoptosis and Acute Kidney Injury via AMPKα-regulated Autophagy Induction.

Li J, Gui Y, Ren J, Liu X, Feng Y, Zeng Z, He W, Yang J, Dai C.

Sci Rep. 2016 Apr 7;6:23975. doi: 10.1038/srep23975.


Repurposing old drugs to chemoprevention: the case of metformin.

Heckman-Stoddard BM, Gandini S, Puntoni M, Dunn BK, DeCensi A, Szabo E.

Semin Oncol. 2016 Feb;43(1):123-133. doi: 10.1053/j.seminoncol.2015.09.009. Epub 2015 Sep 8. Review.


Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma.

Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC.

Curr Mol Med. 2016;16(1):83-90.


Metformin inhibits growth of lung adenocarcinoma cells by inducing apoptosis via the mitochondria-mediated pathway.

Wang J, Gao Q, Wang D, Wang Z, Hu C.

Oncol Lett. 2015 Sep;10(3):1343-1349. Epub 2015 Jul 2.


Metformin for cancer and aging prevention: is it a time to make the long story short?

Anisimov VN.

Oncotarget. 2015 Nov 24;6(37):39398-407. doi: 10.18632/oncotarget.6347.


Metformin Induced AMPK Activation, G0/G1 Phase Cell Cycle Arrest and the Inhibition of Growth of Esophageal Squamous Cell Carcinomas In Vitro and In Vivo.

Cai X, Hu X, Tan X, Cheng W, Wang Q, Chen X, Guan Y, Chen C, Jing X.

PLoS One. 2015 Jul 21;10(7):e0133349. doi: 10.1371/journal.pone.0133349. eCollection 2015.


Targeting LKB1 in cancer - exposing and exploiting vulnerabilities.

Momcilovic M, Shackelford DB.

Br J Cancer. 2015 Aug 11;113(4):574-84. doi: 10.1038/bjc.2015.261. Epub 2015 Jul 21. Review.


Metformin- A Promising Agent for Chemoprevention in BRCA1 Carriers.

Kumar NB, Vadaparampil ST, Mahajan N, Lilienfeld HS, Lee JH, Laronga C, Hakam A, Hein JJ, Egan KM, Arun B, Pal T.

Hereditary Genet. 2012 Jun;1(2). pii: 104. No abstract available.


Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2.

Yue W, Zheng X, Lin Y, Yang CS, Xu Q, Carpizo D, Huang H, DiPaola RS, Tan XL.

Oncotarget. 2015 Aug 28;6(25):21208-24.


Gene-by-Environment Interactions in Pancreatic Cancer: Implications for Prevention.

Jansen RJ, Tan XL, Petersen GM.

Yale J Biol Med. 2015 Jun 1;88(2):115-26. eCollection 2015 Jun. Review.


Metformin suppresses pancreatic tumor growth with inhibition of NFκB/STAT3 inflammatory signaling.

Tan XL, Bhattacharyya KK, Dutta SK, Bamlet WR, Rabe KG, Wang E, Smyrk TC, Oberg AL, Petersen GM, Mukhopadhyay D.

Pancreas. 2015 May;44(4):636-47. doi: 10.1097/MPA.0000000000000308.


The association between type 2 diabetes mellitus and women cancer: the epidemiological evidences and putative mechanisms.

Joung KH, Jeong JW, Ku BJ.

Biomed Res Int. 2015;2015:920618. doi: 10.1155/2015/920618. Epub 2015 Mar 19. Review.


Association of the metformin with the risk of lung cancer: a meta-analysis.

Wang L, Song Y, Wu GN, Yuan DM.

Transl Lung Cancer Res. 2013 Aug;2(4):259-63. doi: 10.3978/j.issn.2218-6751.2013.08.01.


Modulation of cell metabolic pathways and oxidative stress signaling contribute to acquired melphalan resistance in multiple myeloma cells.

Zub KA, Sousa MM, Sarno A, Sharma A, Demirovic A, Rao S, Young C, Aas PA, Ericsson I, Sundan A, Jensen ON, Slupphaug G.

PLoS One. 2015 Mar 13;10(3):e0119857. doi: 10.1371/journal.pone.0119857. eCollection 2015.

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