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TMPRSS2 and MSPL Facilitate Trypsin-Independent Porcine Epidemic Diarrhea Virus Replication in Vero Cells.

Shi W, Fan W, Bai J, Tang Y, Wang L, Jiang Y, Tang L, Liu M, Cui W, Xu Y, Li Y.

Viruses. 2017 May 18;9(5). pii: E114. doi: 10.3390/v9050114.


SheddomeDB: the ectodomain shedding database for membrane-bound shed markers.

Tien WS, Chen JH, Wu KP.

BMC Bioinformatics. 2017 Mar 14;18(Suppl 3):42. doi: 10.1186/s12859-017-1465-7.


Neurovirulent Murine Coronavirus JHM.SD Uses Cellular Zinc Metalloproteases for Virus Entry and Cell-Cell Fusion.

Phillips JM, Gallagher T, Weiss SR.

J Virol. 2017 Mar 29;91(8). pii: e01564-16. doi: 10.1128/JVI.01564-16. Print 2017 Apr 15.


Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidants.

Meyer M, Jaspers I.

Am J Physiol Lung Cell Mol Physiol. 2015 Jun 15;308(12):L1189-201. doi: 10.1152/ajplung.00028.2015. Epub 2015 Apr 17. Review.


TMPRSS2, a novel membrane-anchored mediator in cancer pain.

Lam DK, Dang D, Flynn AN, Hardt M, Schmidt BL.

Pain. 2015 May;156(5):923-30. doi: 10.1097/j.pain.0000000000000130.


Androgen regulation of the TMPRSS2 gene and the effect of a SNP in an androgen response element.

Clinckemalie L, Spans L, Dubois V, Laurent M, Helsen C, Joniau S, Claessens F.

Mol Endocrinol. 2013 Dec;27(12):2028-40. doi: 10.1210/me.2013-1098. Epub 2013 Oct 9.


Loss of PTEN is associated with aggressive behavior in ERG-positive prostate cancer.

Leinonen KA, Saramäki OR, Furusato B, Kimura T, Takahashi H, Egawa S, Suzuki H, Keiger K, Ho Hahm S, Isaacs WB, Tolonen TT, Stenman UH, Tammela TL, Nykter M, Bova GS, Visakorpi T.

Cancer Epidemiol Biomarkers Prev. 2013 Dec;22(12):2333-44. doi: 10.1158/1055-9965.EPI-13-0333-T. Epub 2013 Oct 1.


Recurrent rearrangements in prostate cancer: causes and therapeutic potential.

White NM, Feng FY, Maher CA.

Curr Drug Targets. 2013 Apr;14(4):450-9. Review.


The oncogenic gene fusion TMPRSS2: ERG is not a diagnostic or prognostic marker for ovarian cancer.

Huang L, Schauer IG, Zhang J, Mercado-Uribe I, Deavers MT, Huang J, Liu J.

Int J Clin Exp Pathol. 2011;4(7):644-50. Epub 2011 Sep 15.


Androgen receptor signaling in prostate cancer development and progression.

Lonergan PE, Tindall DJ.

J Carcinog. 2011;10:20. doi: 10.4103/1477-3163.83937. Epub 2011 Aug 23.


Molecular mechanisms of bladder outlet obstruction in transgenic male mice overexpressing aromatase (Cyp19a1).

Lin W, Rahman NA, Lin J, Zhang H, Gou K, Yu W, Zhu D, Li N, Huhtaniemi I, Li X.

Am J Pathol. 2011 Mar;178(3):1233-44. doi: 10.1016/j.ajpath.2010.11.056.


Inhibition of lung serine proteases in mice: a potentially new approach to control influenza infection.

Bahgat MM, Błazejewska P, Schughart K.

Virol J. 2011 Jan 20;8:27. doi: 10.1186/1743-422X-8-27.


Membrane-anchored serine proteases in health and disease.

Antalis TM, Bugge TH, Wu Q.

Prog Mol Biol Transl Sci. 2011;99:1-50. doi: 10.1016/B978-0-12-385504-6.00001-4. Review.


A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry.

Shulla A, Heald-Sargent T, Subramanya G, Zhao J, Perlman S, Gallagher T.

J Virol. 2011 Jan;85(2):873-82. doi: 10.1128/JVI.02062-10. Epub 2010 Nov 10.


The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.

Antalis TM, Buzza MS, Hodge KM, Hooper JD, Netzel-Arnett S.

Biochem J. 2010 Jun 15;428(3):325-46. doi: 10.1042/BJ20100046. Review.


TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate cancer cells.

Chen YW, Lee MS, Lucht A, Chou FP, Huang W, Havighurst TC, Kim K, Wang JK, Antalis TM, Johnson MD, Lin CY.

Am J Pathol. 2010 Jun;176(6):2986-96. doi: 10.2353/ajpath.2010.090665. Epub 2010 Apr 9.


Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors.

Böttcher-Friebertshäuser E, Freuer C, Sielaff F, Schmidt S, Eickmann M, Uhlendorff J, Steinmetzer T, Klenk HD, Garten W.

J Virol. 2010 Jun;84(11):5605-14. doi: 10.1128/JVI.00140-10. Epub 2010 Mar 17.


Using LongSAGE to Detect Biomarkers of Cervical Cancer Potentially Amenable to Optical Contrast Agent Labelling.

Kneller JM, Ehlen T, Matisic JP, Miller D, Van Niekerk D, Lam WL, Marra M, Richards-Kortum R, Follen M, Macaulay C, Jones SJ.

Biomark Insights. 2007 Dec 11;2:447-61.


Quantitative expression of TMPRSS2 transcript in prostate tumor cells reflects TMPRSS2-ERG fusion status.

Mwamukonda K, Chen Y, Ravindranath L, Furusato B, Hu Y, Sterbis J, Osborn D, Rosner I, Sesterhenn IA, McLeod DG, Srivastava S, Petrovics G.

Prostate Cancer Prostatic Dis. 2010 Mar;13(1):47-51. doi: 10.1038/pcan.2009.28. Epub 2009 Jul 14.


Type II transmembrane serine proteases.

Bugge TH, Antalis TM, Wu Q.

J Biol Chem. 2009 Aug 28;284(35):23177-81. doi: 10.1074/jbc.R109.021006. Epub 2009 Jun 1. Review.

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