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Items: 1 to 20 of 30


Autosomal Dominant Polycystic Kidney Patients May Be Predisposed to Various Cardiomyopathies.

Chebib FT, Hogan MC, El-Zoghby ZM, Irazabal MV, Senum SR, Heyer CM, Madsen CD, Cornec-Le Gall E, Behfar A, Harris PC, Torres VE.

Kidney Int Rep. 2017 Jun 6;2(5):913-923. doi: 10.1016/j.ekir.2017.05.014. eCollection 2017 Sep.


Combined renin-angiotensin-aldosterone system blockade and statin therapy effectively reduces the risk of cerebrovascular accident in autosomal dominant polycystic kidney disease: a nationwide population-based cohort study.

Sung PH, Chiang HJ, Lee MS, Chiang JY, Yip HK, Yang YH.

Oncotarget. 2017 Jun 27;8(37):61570-61582. doi: 10.18632/oncotarget.18636. eCollection 2017 Sep 22.


Risk of aortic aneurysm and dissection in patients with autosomal-dominant polycystic kidney disease: a nationwide population-based cohort study.

Sung PH, Yang YH, Chiang HJ, Chiang JY, Chen CJ, Liu CT, Yu CM, Yip HK.

Oncotarget. 2017 Mar 17;8(34):57594-57604. doi: 10.18632/oncotarget.16338. eCollection 2017 Aug 22.


Generation and phenotypic characterization of Pde1a mutant mice.

Wang X, Yamada S, LaRiviere WB, Ye H, Bakeberg JL, Irazabal MV, Chebib FT, van Deursen J, Harris PC, Sussman CR, Behfar A, Ward CJ, Torres VE.

PLoS One. 2017 Jul 27;12(7):e0181087. doi: 10.1371/journal.pone.0181087. eCollection 2017.


Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models.

Ameku T, Taura D, Sone M, Numata T, Nakamura M, Shiota F, Toyoda T, Matsui S, Araoka T, Yasuno T, Mae S, Kobayashi H, Kondo N, Kitaoka F, Amano N, Arai S, Ichisaka T, Matsuura N, Inoue S, Yamamoto T, Takahashi K, Asaka I, Yamada Y, Ubara Y, Muso E, Fukatsu A, Watanabe A, Sato Y, Nakahata T, Mori Y, Koizumi A, Nakao K, Yamanaka S, Osafune K.

Sci Rep. 2016 Jul 15;6:30013. doi: 10.1038/srep30013.


The functions of TRPP2 in the vascular system.

Du J, Fu J, Xia XM, Shen B.

Acta Pharmacol Sin. 2016 Jan;37(1):13-8. doi: 10.1038/aps.2015.126. Review.


Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity.

Varela A, Piperi C, Sigala F, Agrogiannis G, Davos CH, Andri MA, Manopoulos C, Tsangaris S, Basdra EK, Papavassiliou AG.

Sci Rep. 2015 Aug 19;5:13461. doi: 10.1038/srep13461.


Vascular complications in autosomal dominant polycystic kidney disease.

Perrone RD, Malek AM, Watnick T.

Nat Rev Nephrol. 2015 Oct;11(10):589-98. doi: 10.1038/nrneph.2015.128. Epub 2015 Aug 11. Review.


Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease.

Saigusa T, Dang Y, Bunni MA, Amria MY, Steele SL, Fitzgibbon WR, Bell PD.

Physiol Rep. 2015 May;3(5). pii: e12405. doi: 10.14814/phy2.12405.


Molecular pathways and therapies in autosomal-dominant polycystic kidney disease.

Saigusa T, Bell PD.

Physiology (Bethesda). 2015 May;30(3):195-207. doi: 10.1152/physiol.00032.2014. Review.


Transient receptor potential channels in the vasculature.

Earley S, Brayden JE.

Physiol Rev. 2015 Apr;95(2):645-90. doi: 10.1152/physrev.00026.2014. Review.


Endothelial cilia are essential for developmental vascular integrity in zebrafish.

Kallakuri S, Yu JA, Li J, Li Y, Weinstein BM, Nicoli S, Sun Z.

J Am Soc Nephrol. 2015 Apr;26(4):864-75. doi: 10.1681/ASN.2013121314. Epub 2014 Sep 11.


Risk of intracranial hemorrhage associated with autosomal dominant polycystic kidney disease in patients with end stage renal disease.

Yoo DJ, Agodoa L, Yuan CM, Abbott KC, Nee R.

BMC Nephrol. 2014 Feb 26;15:39. doi: 10.1186/1471-2369-15-39.


A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.

Liu D, Wang CJ, Judge DP, Halushka MK, Ni J, Habashi JP, Moslehi J, Bedja D, Gabrielson KL, Xu H, Qian F, Huso D, Dietz HC, Germino GG, Watnick T.

J Am Soc Nephrol. 2014 Jan;25(1):81-91. doi: 10.1681/ASN.2012050486. Epub 2013 Sep 26.


The genetics of vascular complications in autosomal dominant polycystic kidney disease (ADPKD).

Rossetti S, Harris PC.

Curr Hypertens Rev. 2013 Feb;9(1):37-43. Review.


Smooth muscle cell transient receptor potential polycystin-2 (TRPP2) channels contribute to the myogenic response in cerebral arteries.

Narayanan D, Bulley S, Leo MD, Burris SK, Gabrick KS, Boop FA, Jaggar JH.

J Physiol. 2013 Oct 15;591(20):5031-46. doi: 10.1113/jphysiol.2013.258319. Epub 2013 Jul 15.


Aortic disease in the young: genetic aneurysm syndromes, connective tissue disorders, and familial aortic aneurysms and dissections.

Cury M, Zeidan F, Lobato AC.

Int J Vasc Med. 2013;2013:267215. doi: 10.1155/2013/267215. Epub 2013 Jan 14.


Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy.

Paavola J, Schliffke S, Rossetti S, Kuo IY, Yuan S, Sun Z, Harris PC, Torres VE, Ehrlich BE.

J Mol Cell Cardiol. 2013 May;58:199-208. doi: 10.1016/j.yjmcc.2013.01.015. Epub 2013 Jan 30.


Extended follow-up of unruptured intracranial aneurysms detected by presymptomatic screening in patients with autosomal dominant polycystic kidney disease.

Irazabal MV, Huston J 3rd, Kubly V, Rossetti S, Sundsbak JL, Hogan MC, Harris PC, Brown RD Jr, Torres VE.

Clin J Am Soc Nephrol. 2011 Jun;6(6):1274-85. doi: 10.2215/CJN.09731110. Epub 2011 May 5.

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