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Mechanism of Hepatocyte Apoptosis.

Cao L, Quan XB, Zeng WJ, Yang XO, Wang MJ.

J Cell Death. 2016 Dec 29;9:19-29. doi: 10.4137/JCD.S39824. eCollection 2016. Review.


Hepatitis B virus molecular biology and pathogenesis.

Lamontagne RJ, Bagga S, Bouchard MJ.

Hepatoma Res. 2016;2:163-186. doi: 10.20517/2394-5079.2016.05. Epub 2016 Jul 1.


Hepatitis B virus-triggered autophagy targets TNFRSF10B/death receptor 5 for degradation to limit TNFSF10/TRAIL response.

Shin GC, Kang HS, Lee AR, Kim KH.

Autophagy. 2016 Dec;12(12):2451-2466. Epub 2016 Oct 14.


Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response.

Yeganeh B, Rezaei Moghadam A, Alizadeh J, Wiechec E, Alavian SM, Hashemi M, Geramizadeh B, Samali A, Bagheri Lankarani K, Post M, Peymani P, Coombs KM, Ghavami S.

World J Gastroenterol. 2015 Dec 21;21(47):13225-39. doi: 10.3748/wjg.v21.i47.13225.


A novel mutant 10Ala/Arg together with mutant 144Ser/Arg of hepatitis B virus X protein involved in hepatitis B virus-related hepatocarcinogenesis in HepG2 cell lines.

Shi Y, Wang J, Wang Y, Wang A, Guo H, Wei F, Mehta SR, Espitia S, Smith DM, Liu L, Zhang Y, Chen D.

Cancer Lett. 2016 Feb 28;371(2):285-91. doi: 10.1016/j.canlet.2015.12.008. Epub 2015 Dec 17.


The Chinese medicine Sini-San inhibits HBx-induced migration and invasiveness of human hepatocellular carcinoma cells.

Lin HJ, Kao ST, Siao YM, Yeh CC.

BMC Complement Altern Med. 2015 Oct 7;15:348. doi: 10.1186/s12906-015-0870-6.


Immune-mediated Liver Injury in Hepatitis B Virus Infection.

Oh IS, Park SH.

Immune Netw. 2015 Aug;15(4):191-8. doi: 10.4110/in.2015.15.4.191. Epub 2015 Aug 26. Review.


Hepatitis B virus infection and intrahepatic cholangiocarcinoma.

Zhou HB, Hu JY, Hu HP.

World J Gastroenterol. 2014 May 21;20(19):5721-9. doi: 10.3748/wjg.v20.i19.5721. Review.


Defective antiviral CD8 T-cell response and viral clearance in the absence of c-Jun N-terminal kinases.

Wang YQ, Ma X, Lu L, Zhao L, Zhang X, Xu Q, Wang Y.

Immunology. 2014 Aug;142(4):603-13. doi: 10.1111/imm.12270.


Viruses as modulators of mitochondrial functions.

Anand SK, Tikoo SK.

Adv Virol. 2013;2013:738794. doi: 10.1155/2013/738794. Epub 2013 Oct 24. Review.


Hepatitis B virus inhibits apoptosis of hepatoma cells by sponging the MicroRNA 15a/16 cluster.

Liu N, Zhang J, Jiao T, Li Z, Peng J, Cui Z, Ye X.

J Virol. 2013 Dec;87(24):13370-8. doi: 10.1128/JVI.02130-13. Epub 2013 Oct 2.


Primary hepatocytes and their cultures in liver apoptosis research.

Vinken M, Maes M, Oliveira AG, Cogliati B, Marques PE, Menezes GB, Dagli ML, Vanhaecke T, Rogiers V.

Arch Toxicol. 2014 Feb;88(2):199-212. doi: 10.1007/s00204-013-1123-4. Epub 2013 Sep 8. Review.


Modulation of apoptotic signaling by the hepatitis B virus X protein.

Rawat S, Clippinger AJ, Bouchard MJ.

Viruses. 2012 Nov 8;4(11):2945-72. doi: 10.3390/v4112945. Review.


Hepatitis B virus alters the antioxidant system in transgenic mice and sensitizes hepatocytes to Fas signaling.

Wang Q, Na B, Ou JH, Pulliam L, Yen TS.

PLoS One. 2012;7(5):e36818. doi: 10.1371/journal.pone.0036818. Epub 2012 May 11.


HBx activates FasL and mediates HepG2 cell apoptosis through MLK3-MKK7-JNKs signal module.

Tang RX, Kong FY, Fan BF, Liu XM, You HJ, Zhang P, Zheng KY.

World J Gastroenterol. 2012 Apr 7;18(13):1485-95. doi: 10.3748/wjg.v18.i13.1485.


Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development.

Yip WK, Cheng AS, Zhu R, Lung RW, Tsang DP, Lau SS, Chen Y, Sung JG, Lai PB, Ng EK, Yu J, Wong N, To KF, Wong VW, Sung JJ, Chan HL.

PLoS One. 2011;6(8):e22888. doi: 10.1371/journal.pone.0022888. Epub 2011 Aug 4.


Hepatitis B virus X protein promotes hepatoma cell proliferation via upregulation of MEKK2.

Kong GY, Zhang JP, Zhang S, Shan CL, Ye LH, Zhang XD.

Acta Pharmacol Sin. 2011 Sep;32(9):1173-80. doi: 10.1038/aps.2011.52. Epub 2011 Aug 1.


Apoptosis of hepatitis B virus-infected hepatocytes prevents release of infectious virus.

Arzberger S, Hösel M, Protzer U.

J Virol. 2010 Nov;84(22):11994-2001. doi: 10.1128/JVI.00653-10. Epub 2010 Aug 18.


Viral hepatocarcinogenesis.

Tsai WL, Chung RT.

Oncogene. 2010 Apr 22;29(16):2309-24. doi: 10.1038/onc.2010.36. Epub 2010 Mar 15. Review.


Hepatitis B virus protein X-induced expression of the CXC chemokine IP-10 is mediated through activation of NF-kappaB and increases migration of leukocytes.

Zhou Y, Wang S, Ma JW, Lei Z, Zhu HF, Lei P, Yang ZS, Zhang B, Yao XX, Shi C, Sun LF, Wu XW, Ning Q, Shen GX, Huang B.

J Biol Chem. 2010 Apr 16;285(16):12159-68. doi: 10.1074/jbc.M109.067629. Epub 2010 Feb 17.

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