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Items: 11

1.

Structure- and conformation-activity studies of nociceptin/orphanin FQ receptor dimeric ligands.

Pacifico S, Carotenuto A, Brancaccio D, Novellino E, Marzola E, Ferrari F, Cerlesi MC, Trapella C, Preti D, Salvadori S, Calò G, Guerrini R.

Sci Rep. 2017 Apr 6;7:45817. doi: 10.1038/srep45817.

2.

Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.

Toll L, Bruchas MR, Calo' G, Cox BM, Zaveri NT.

Pharmacol Rev. 2016 Apr;68(2):419-57. doi: 10.1124/pr.114.009209. Epub 2016 Mar 8. Review.

3.

Pharmacological Profile of Nociceptin/Orphanin FQ Receptors Interacting with G-Proteins and β-Arrestins 2.

Malfacini D, Ambrosio C, Gro' MC, Sbraccia M, Trapella C, Guerrini R, Bonora M, Pinton P, Costa T, Calo' G.

PLoS One. 2015 Aug 6;10(8):e0132865. doi: 10.1371/journal.pone.0132865. eCollection 2015.

4.

Structural requirements of N-substituted spiropiperidine analogues as agonists of nociceptin/orphanin FQ receptor.

Bao P, Zhang X, Ren H, Li Y, Mu Z, Zhang S, Li G, Yang L.

Int J Mol Sci. 2011;12(12):8961-81. doi: 10.3390/ijms12128961. Epub 2011 Dec 6.

5.

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency.

Harrison RS, Shepherd NE, Hoang HN, Ruiz-Gómez G, Hill TA, Driver RW, Desai VS, Young PR, Abbenante G, Fairlie DP.

Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11686-91. doi: 10.1073/pnas.1002498107. Epub 2010 Jun 11.

6.

Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

Ko MC, Naughton NN.

J Pain. 2009 May;10(5):509-16. doi: 10.1016/j.jpain.2008.11.006. Epub 2009 Feb 23.

7.

In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptor.

Rizzi A, Spagnolo B, Wainford RD, Fischetti C, Guerrini R, Marzola G, Baldisserotto A, Salvadori S, Regoli D, Kapusta DR, Calo G.

Peptides. 2007 Jun;28(6):1240-51. Epub 2007 May 6.

8.

Activation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux.

D'Agostino B, Marrocco G, De Nardo M, Calò G, Guerrini R, Gallelli L, Advenier C, Rossi F.

Br J Pharmacol. 2005 Mar;144(6):813-20.

10.

Pharmacological characterization of the novel nociceptin/orphanin FQ receptor ligand, ZP120: in vitro and in vivo studies in mice.

Rizzi A, Rizzi D, Marzola G, Regoli D, Larsen BD, Petersen JS, Calo' G.

Br J Pharmacol. 2002 Oct;137(3):369-74.

11.

[Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor.

Calo G, Rizzi A, Rizzi D, Bigoni R, Guerrini R, Marzola G, Marti M, McDonald J, Morari M, Lambert DG, Salvadori S, Regoli D.

Br J Pharmacol. 2002 May;136(2):303-11.

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