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Items: 1 to 20 of 123

1.

Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity.

Roth S, Bergmann H, Jaeger M, Yeroslaviz A, Neumann K, Koenig PA, Prazeres da Costa C, Vanes L, Kumar V, Johnson M, Menacho-Márquez M, Habermann B, Tybulewicz VL, Netea M, Bustelo XR, Ruland J.

Cell Rep. 2016 Dec 6;17(10):2572-2583. doi: 10.1016/j.celrep.2016.11.018.

2.

FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions.

Hodgson L, Spiering D, Sabouri-Ghomi M, Dagliyan O, DerMardirossian C, Danuser G, Hahn KM.

Nat Chem Biol. 2016 Oct;12(10):802-9. doi: 10.1038/nchembio.2145. Epub 2016 Aug 8.

3.

A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation.

Kassem S, Gaud G, Bernard I, Benamar M, Dejean AS, Liblau R, Fournié GJ, Colacios C, Malissen B, Saoudi A.

PLoS Genet. 2016 Jul 20;12(7):e1006185. doi: 10.1371/journal.pgen.1006185. eCollection 2016 Jul.

4.

Tyrosine Phosphorylation of SGEF Regulates RhoG Activity and Cell Migration.

Okuyama Y, Umeda K, Negishi M, Katoh H.

PLoS One. 2016 Jul 20;11(7):e0159617. doi: 10.1371/journal.pone.0159617. eCollection 2016.

5.

Allosteric properties of PH domains in Arf regulatory proteins.

Roy NS, Yohe ME, Randazzo PA, Gruschus JM.

Cell Logist. 2016 Apr 26;6(2):e1181700. eCollection 2016 Apr-Jun. Review.

6.

PAR3-aPKC regulates Tiam1 by modulating suppressive internal interactions.

Matsuzawa K, Akita H, Watanabe T, Kakeno M, Matsui T, Wang S, Kaibuchi K.

Mol Biol Cell. 2016 May 1;27(9):1511-23. doi: 10.1091/mbc.E15-09-0670. Epub 2016 Mar 3.

7.

Cooperative Control of Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling by an Unusual Array of Redundant Repressive Elements.

Jattani RP, Tritapoe JM, Pomerantz JL.

J Biol Chem. 2016 Apr 15;291(16):8324-36. doi: 10.1074/jbc.M115.683714. Epub 2016 Feb 16.

8.

Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.

Lissanu Deribe Y, Shi Y, Rai K, Nezi L, Amin SB, Wu CC, Akdemir KC, Mahdavi M, Peng Q, Chang QE, Hornigold K, Arold ST, Welch HC, Garraway LA, Chin L.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1296-305. doi: 10.1073/pnas.1513801113. Epub 2016 Feb 16.

9.

A Conserved GEF for Rho-Family GTPases Acts in an EGF Signaling Pathway to Promote Sleep-like Quiescence in Caenorhabditis elegans.

Fry AL, Laboy JT, Huang H, Hart AC, Norman KR.

Genetics. 2016 Mar;202(3):1153-66. doi: 10.1534/genetics.115.183038. Epub 2016 Jan 22.

10.

p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase.

Barrows D, Schoenfeld SM, Hodakoski C, Silkov A, Honig B, Couvillon A, Shymanets A, Nürnberg B, Asara JM, Parsons R.

J Biol Chem. 2015 Nov 27;290(48):28915-31. doi: 10.1074/jbc.M115.668244. Epub 2015 Oct 5.

11.

Vav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancer.

Katzav S.

Oncotarget. 2015 Oct 6;6(30):28731-42. doi: 10.18632/oncotarget.5086. Review.

12.

Constrained peptides as miniature protein structures.

Yin H.

ISRN Biochem. 2012 Sep 26;2012:692190. doi: 10.5402/2012/692190. eCollection 2012. Review.

13.

Crossroads of PI3K and Rac pathways.

Campa CC, Ciraolo E, Ghigo A, Germena G, Hirsch E.

Small GTPases. 2015;6(2):71-80. doi: 10.4161/21541248.2014.989789. Epub 2015 May 5. Review.

14.

Lipid and Protein Co-Regulation of PI3K Effectors Akt and Itk in Lymphocytes.

Wang X, Hills LB, Huang YH.

Front Immunol. 2015 Mar 13;6:117. doi: 10.3389/fimmu.2015.00117. eCollection 2015. Review.

15.

Vav family exchange factors: an integrated regulatory and functional view.

Bustelo XR.

Small GTPases. 2014;5(2):9. doi: 10.4161/21541248.2014.973757. Review.

16.

Mutation of Vav1 adaptor region reveals a new oncogenic activation.

Razanadrakoto L, Cormier F, Laurienté V, Dondi E, Gardano L, Katzav S, Guittat L, Varin-Blank N.

Oncotarget. 2015 Feb 10;6(4):2524-37.

17.

Function and regulation of the Rho guanine nucleotide exchange factor Trio.

Schmidt S, Debant A.

Small GTPases. 2014;5:e29769. doi: 10.4161/sgtp.29769. Epub 2014 Jul 2. Review.

18.

Tyrosine phosphorylation within the intrinsically disordered cytosolic domains of the B-cell receptor: an NMR-based structural analysis.

Rosenlöw J, Isaksson L, Mayzel M, Lengqvist J, Orekhov VY.

PLoS One. 2014 Apr 25;9(4):e96199. doi: 10.1371/journal.pone.0096199. eCollection 2014.

19.

Phosphorylation-mediated regulation of GEFs for RhoA.

Patel M, Karginov AV.

Cell Adh Migr. 2014;8(1):11-8. doi: 10.4161/cam.28058. Epub 2013 Jan 1. Review.

20.

Conditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function.

Jakob U, Kriwacki R, Uversky VN.

Chem Rev. 2014 Jul 9;114(13):6779-805. doi: 10.1021/cr400459c. Epub 2014 Feb 6. Review. No abstract available.

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